BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Breast cancer AND TFEB, TCFEB, 7942, ENSG00000112561, P19484, AlphaTFEB
36 results:

  • 1. ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.
    Koh M; Lim H; Jin H; Kim M; Hong Y; Hwang YK; Woo Y; Kim ES; Kim SY; Kim KM; Lim HK; Jung J; Kang S; Park B; Lee HB; Han W; Lee MS; Moon A
    Autophagy; 2024 Mar; 20(3):659-674. PubMed ID: 38290972
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Novel exosomal circEGFR facilitates triple negative breast cancer autophagy via promoting tfeb nuclear trafficking and modulating miR-224-5p/ATG13/ULK1 feedback loop.
    Song H; Zhao Z; Ma L; Zhao W; Hu Y; Song Y
    Oncogene; 2024 Mar; 43(11):821-836. PubMed ID: 38280941
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma.
    Augustin RC; Newman S; Li A; Joy M; Lyons M; Pham MP; Lucas P; Smith K; Sander C; Isett B; Davar D; Najjar YG; Zarour HM; Kirkwood JM; Luke JJ; Bao R
    J Immunother Cancer; 2023 Oct; 11(10):. PubMed ID: 37857525
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Resistance to abemaciclib is associated with increased metastatic potential and lysosomal protein deregulation in breast cancer cells.
    Scheidemann ER; Demas DM; Hou C; Ma J; He W; Sharma G; Schultz E; Weilbaecher KN; Shajahan-Haq AN
    Mol Carcinog; 2024 Feb; 63(2):209-223. PubMed ID: 37818798
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Neratinib is a tfeb and TFE3 activator that potentiates autophagy and unbalances energy metabolism in ERBB2+ breast cancer cells.
    Bellese G; Tagliatti E; Gagliani MC; Santamaria S; Arnaldi P; Falletta P; Rusmini P; Matteoli M; Castagnola P; Cortese K
    Biochem Pharmacol; 2023 Jul; 213():115633. PubMed ID: 37269887
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A new glance at autophagolysosomal-dependent or -independent function of transcriptional factor EB in human cancer.
    Wang T; Qin Y; Ye Z; Jing DS; Fan GX; Liu MQ; Zhuo QF; Ji SR; Chen XM; Yu XJ; Xu XW; Li Z
    Acta Pharmacol Sin; 2023 Aug; 44(8):1536-1548. PubMed ID: 37012494
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Kaempferol with Verapamil impeded panoramic chemoevasion pathways in breast cancer through ROS overproduction and disruption of lysosomal biogenesis.
    Nandi SK; Chatterjee N; Roychowdhury T; Pradhan A; Moiz S; Manna K; Sarkar DK; Dhar P; Dutta A; Mukhopadhyay S; Bhattacharya R
    Phytomedicine; 2023 May; 113():154689. PubMed ID: 36921428
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Loss of transcription factor EB dysregulates the G1/S transition and DNA replication in mammary epithelial cells.
    Slade L; Biswas D; Kienesberger PC; Pulinilkunnil T
    J Biol Chem; 2022 Dec; 298(12):102692. PubMed ID: 36372230
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Covalent JNK Inhibitor, JNK-IN-8, Suppresses Tumor Growth in Triple-Negative breast cancer by Activating tfeb- and TFE3-Mediated Lysosome Biogenesis and Autophagy.
    Soleimani M; Somma A; Kaoud T; Goyal R; Bustamante J; Wylie DC; Holay N; Looney A; Giri U; Triplett T; Dalby K; Kowalski J; Eckhardt SG; Van Den Berg C
    Mol Cancer Ther; 2022 Oct; 21(10):1547-1560. PubMed ID: 35977156
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Quercetin Promotes tfeb Nuclear Translocation and Activates Lysosomal Degradation of Ferritin to Induce Ferroptosis in breast cancer Cells.
    An S; Hu M
    Comput Intell Neurosci; 2022; 2022():5299218. PubMed ID: 35898781
    [No Abstract]    [Full Text] [Related]  

  • 11. Alteration of Trop-2 expression in breast cancer cells by clinically used therapeutic agents and acquired tamoxifen resistance.
    Zhu J; Wu W; Togashi Y; Taira Nihira N; Johmura Y; Zhu D; Nakanishi M; Miyoshi Y; Ohta T
    Breast Cancer; 2022 Nov; 29(6):1076-1087. PubMed ID: 35882754
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. A racemosin B derivative, C25, suppresses breast cancer growth via lysosomal membrane permeabilization and inhibition of autophagic flux.
    Xiao X; Chung PED; Xu M; Hu A; Ju Y; Yang X; Song J; Song J; Wang C; Zacksenhaus E; Liu S; He Z; Ben-David Y
    Biochem Pharmacol; 2022 Jul; 201():115060. PubMed ID: 35513042
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Inhibition of fucoidan on breast cancer cells and potential enhancement of their sensitivity to chemotherapy by regulating autophagy.
    Zhang N; Xue M; Wang Q; Liang H; Yang J; Pei Z; Qin K
    Phytother Res; 2021 Dec; 35(12):6904-6917. PubMed ID: 34687482
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. tfeb, SIRT1, CARM1, Beclin-1 expression and PITX2 methylation in breast cancer chemoresistance: a retrospective study.
    Bertozzi S; Londero AP; Viola L; Orsaria M; Bulfoni M; Marzinotto S; Corradetti B; Baccarani U; Cesselli D; Cedolini C; Mariuzzi L
    BMC Cancer; 2021 Oct; 21(1):1118. PubMed ID: 34663249
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Endolysosomal Cation Channels and MITF in Melanocytes and Melanoma.
    Abrahamian C; Grimm C
    Biomolecules; 2021 Jul; 11(7):. PubMed ID: 34356645
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.
    Rühl P; Rosato AS; Urban N; Gerndt S; Tang R; Abrahamian C; Leser C; Sheng J; Jha A; Vollmer G; Schaefer M; Bracher F; Grimm C
    Sci Rep; 2021 Apr; 11(1):8313. PubMed ID: 33859333
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy.
    Wu Q; Tian AL; Durand S; Aprahamian F; Nirmalathasan N; Xie W; Liu P; Zhao L; Zhang S; Pan H; Carmona-Gutierrez D; Madeo F; Tu Y; Kepp O; Kroemer G
    Cell Death Dis; 2020 Nov; 11(11):1015. PubMed ID: 33243998
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Lysosomal Biogenesis and Implications for Hydroxychloroquine Disposition.
    Collins KP; Witta S; Coy JW; Pang Y; Gustafson DL
    J Pharmacol Exp Ther; 2021 Feb; 376(2):294-305. PubMed ID: 33172973
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Improved Autophagic Flux in Escapers from Doxorubicin-Induced Senescence/Polyploidy of breast cancer Cells.
    Bojko A; Staniak K; Czarnecka-Herok J; Sunderland P; Dudkowska M; Śliwińska MA; Salmina K; Sikora E
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32846959
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Enhanced lysosomal function is critical for paclitaxel resistance in cancer cells: reversed by artesunate.
    Li Z; Zhu YT; Xiang M; Qiu JL; Luo SQ; Lin F
    Acta Pharmacol Sin; 2021 Apr; 42(4):624-632. PubMed ID: 32704040
    [TBL] [Abstract] [Full Text] [Related]  


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