BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Breast cancer AND USP8, FLJ34456, 9101, ENSG00000138592, KIAA0055, P40818, MGC129718, UBPY, HumORF8
25 results:

  • 1. The discovery of potent USP2/usp8 dual-target inhibitors for the treatment of breast cancer via structure guided optimization of ML364.
    Tian Y; Liu K; Wu D; Wu L; Xu Q; Wei W; Li Z; Du Q; Bian J
    Eur J Med Chem; 2024 Mar; 268():116275. PubMed ID: 38452725
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. usp8 promotes gemcitabine resistance of pancreatic cancer via deubiquitinating and stabilizing Nrf2.
    Cui J; Guo Y; Yin T; Gou S; Xiong J; Liang X; Lu C; Peng T
    Biomed Pharmacother; 2023 Oct; 166():115359. PubMed ID: 37639742
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Patterns of care and outcomes of risk reducing surgery in women with pathogenic variants in non-BRCA and Lynch syndrome ovarian cancer susceptibility genes.
    Schwartz ZP; Li AJ; Walsh CS; Rimel BJ; Alvarado MM; Lentz SE; Cass I
    Gynecol Oncol; 2023 Jun; 173():1-7. PubMed ID: 37030072
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Revealing the Potential Markers of N(4)-Acetylcytidine through acRIP-seq in Triple-Negative breast cancer.
    Zhang X; Zeng J; Wang J; Yang Z; Gao S; Liu H; Li G; Zhang X; Gu Y; Pang D
    Genes (Basel); 2022 Dec; 13(12):. PubMed ID: 36553667
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. usp8 promotes cancer progression and extracellular vesicle-mediated CD8+ T cell exhaustion by deubiquitinating the TGF-β receptor TβRII.
    Xie F; Zhou X; Li H; Su P; Liu S; Li R; Zou J; Wei X; Pan C; Zhang Z; Zheng M; Liu Z; Meng X; Ovaa H; Ten Dijke P; Zhou F; Zhang L
    EMBO J; 2022 Aug; 41(16):e108791. PubMed ID: 35811497
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Discovery of Potent Small-Molecule usp8 Inhibitors for the Treatment of breast cancer through Regulating ERα Expression.
    Tian Y; Liu K; Liu R; Qiu Z; Xu Y; Wei W; Xu X; Wang J; Ding H; Li Z; Bian J
    J Med Chem; 2022 Jul; 65(13):8914-8932. PubMed ID: 35786929
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. usp8 promotes tumor cell migration through activating the JNK pathway.
    Zhao Y; Peng D; Liu Y; Zhang Q; Liu B; Deng Y; Ding W; Zhou Z; Liu Q
    Cell Death Dis; 2022 Mar; 13(3):286. PubMed ID: 35361778
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Stereotactic Vacuum-Assisted Needle Biopsy Outcomes of Non-calcified Mammographic Lesions.
    Porembka JH; Compton L; Schmidt S; Polat D; Xi Y; Sarode V; Dogan BE
    Acad Radiol; 2021 Dec; 28(12):1739-1747. PubMed ID: 32782221
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer.
    Shin S; Kim K; Kim HR; Ylaya K; Do SI; Hewitt SM; Park HS; Roe JS; Chung JY; Song J
    Cell Death Differ; 2020 Apr; 27(4):1341-1354. PubMed ID: 31527799
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The expression of ubiquitin-specific peptidase 8 and its prognostic role in patients with breast cancer.
    Qiu H; Kong J; Cheng Y; Li G
    J Cell Biochem; 2018 Dec; 119(12):10051-10058. PubMed ID: 30132974
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The ubiquitin-specific protease usp8 deubiquitinates and stabilizes Cx43.
    Sun J; Hu Q; Peng H; Peng C; Zhou L; Lu J; Huang C
    J Biol Chem; 2018 May; 293(21):8275-8284. PubMed ID: 29626091
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Flavonoids from Erythrina schliebenii.
    Nyandoro SS; Munissi JJ; Kombo M; Mgina CA; Pan F; Gruhonjic A; Fitzpatrick P; Lu Y; Wang B; Rissanen K; Erdélyi M
    J Nat Prod; 2017 Feb; 80(2):377-383. PubMed ID: 28112509
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation.
    Le Clorennec C; Lazrek Y; Dubreuil O; Larbouret C; Poul MA; Mondon P; Melino G; Pèlegrin A; Chardès T
    Oncotarget; 2016 Jun; 7(24):37013-37029. PubMed ID: 27203743
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Pharmacokinetics and pharmacogenetics of capecitabine and its metabolites following replicate administration of two 500 mg tablet formulations.
    Queckenberg C; Erlinghagen V; Baken BC; Van Os SH; Wargenau M; Kubeš V; Peroutka R; Novotný V; Fuhr U
    Cancer Chemother Pharmacol; 2015 Nov; 76(5):1081-91. PubMed ID: 26242222
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. BRUCE regulates DNA double-strand break response by promoting usp8 deubiquitination of BRIT1.
    Ge C; Che L; Ren J; Pandita RK; Lu J; Li K; Pandita TK; Du C
    Proc Natl Acad Sci U S A; 2015 Mar; 112(11):E1210-9. PubMed ID: 25733871
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The excess mortality related to cardiovascular diseases and cancer among adults pharmacologically treated for diabetes--the 2001-2006 ENTRED cohort.
    Romon I; Rey G; Mandereau-Bruno L; Weill A; Jougla E; Eschwège E; Simon D; Druet C; Fagot-Campagna A
    Diabet Med; 2014 Aug; 31(8):946-53. PubMed ID: 24627972
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Association of the tumor necrosis factor-alpha -308G>A polymorphism with breast cancer in Mexican women.
    Gómez Flores-Ramos L; Escoto-De Dios A; Puebla-Pérez AM; Figuera-Villanueva LE; Ramos-Silva A; Ramírez-Patiño R; Delgado-Saucedo JI; Salas-González E; Zúñiga-González GM; Alonzo-Rojo A; Gutiérrez-Hurtado I; Gallegos-Arreola MP
    Genet Mol Res; 2013 Nov; 12(4):5680-93. PubMed ID: 24301937
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Predicted cancer risks induced by computed tomography examinations during childhood, by a quantitative risk assessment approach.
    Journy N; Ancelet S; Rehel JL; Mezzarobba M; Aubert B; Laurier D; Bernier MO
    Radiat Environ Biophys; 2014 Mar; 53(1):39-54. PubMed ID: 24105448
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. A case-matched study of stereotactic radiosurgery for patients with multiple brain metastases: comparing treatment results for 1-4 vs ≥ 5 tumors: clinical article.
    Yamamoto M; Kawabe T; Sato Y; Higuchi Y; Nariai T; Barfod BE; Kasuya H; Urakawa Y
    J Neurosurg; 2013 Jun; 118(6):1258-68. PubMed ID: 23600938
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Association between C-reactive protein and risk of cancer: a meta-analysis of prospective cohort studies.
    Guo YZ; Pan L; Du CJ; Ren DQ; Xie XM
    Asian Pac J Cancer Prev; 2013; 14(1):243-8. PubMed ID: 23534731
    [TBL] [Abstract] [Full Text] [Related]  


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