BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Breast cancer AND USP8, FLJ34456, 9101, ENSG00000138592, KIAA0055, P40818, MGC129718, UBPY, HumORF8 AND Treatment
8 results:

  • 1. The discovery of potent USP2/usp8 dual-target inhibitors for the treatment of breast cancer via structure guided optimization of ML364.
    Tian Y; Liu K; Wu D; Wu L; Xu Q; Wei W; Li Z; Du Q; Bian J
    Eur J Med Chem; 2024 Mar; 268():116275. PubMed ID: 38452725
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Discovery of Potent Small-Molecule usp8 Inhibitors for the treatment of breast cancer through Regulating ERα Expression.
    Tian Y; Liu K; Liu R; Qiu Z; Xu Y; Wei W; Xu X; Wang J; Ding H; Li Z; Bian J
    J Med Chem; 2022 Jul; 65(13):8914-8932. PubMed ID: 35786929
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. usp8 promotes tumor cell migration through activating the JNK pathway.
    Zhao Y; Peng D; Liu Y; Zhang Q; Liu B; Deng Y; Ding W; Zhou Z; Liu Q
    Cell Death Dis; 2022 Mar; 13(3):286. PubMed ID: 35361778
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation.
    Le Clorennec C; Lazrek Y; Dubreuil O; Larbouret C; Poul MA; Mondon P; Melino G; Pèlegrin A; Chardès T
    Oncotarget; 2016 Jun; 7(24):37013-37029. PubMed ID: 27203743
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Pharmacokinetics and pharmacogenetics of capecitabine and its metabolites following replicate administration of two 500 mg tablet formulations.
    Queckenberg C; Erlinghagen V; Baken BC; Van Os SH; Wargenau M; Kubeš V; Peroutka R; Novotný V; Fuhr U
    Cancer Chemother Pharmacol; 2015 Nov; 76(5):1081-91. PubMed ID: 26242222
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A case-matched study of stereotactic radiosurgery for patients with multiple brain metastases: comparing treatment results for 1-4 vs ≥ 5 tumors: clinical article.
    Yamamoto M; Kawabe T; Sato Y; Higuchi Y; Nariai T; Barfod BE; Kasuya H; Urakawa Y
    J Neurosurg; 2013 Jun; 118(6):1258-68. PubMed ID: 23600938
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Aggressive treatment for hepatic metastases from breast cancer: results from a single center.
    Polistina F; Costantin G; Febbraro A; Robusto E; Ambrosino G
    World J Surg; 2013 Jun; 37(6):1322-32. PubMed ID: 23474856
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1.
    Cao Z; Wu X; Yen L; Sweeney C; Carraway KL
    Mol Cell Biol; 2007 Mar; 27(6):2180-8. PubMed ID: 17210635
    [TBL] [Abstract] [Full Text] [Related]  


    of 1.