Terms: = Breast cancer AND WRN, RECQL2, 7486, ENSG00000165392, Q14191, RECQ3 AND Treatment
10 results:
1. Non-enzymatic function of wrn RECQL helicase regulates removal of topoisomerase-I-DNA covalent complexes and triggers NF-κB signaling in cancer.
Gupta P; Majumdar AG; Patro BS
Aging Cell; 2022 Jun; 21(6):e13625. PubMed ID: 35582959
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2. The wrn helicase: resolving a new target in microsatellite unstable cancers.
van Wietmarschen N; Nathan WJ; Nussenzweig A
Curr Opin Genet Dev; 2021 Dec; 71():34-38. PubMed ID: 34284257
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3. Werner Syndrome Protein Expression in breast cancer.
Savva C; Sadiq M; Sheikh O; Karim S; Trivedi S; Green AR; Rakha EA; Madhusudan S; Arora A
Clin Breast Cancer; 2021 Feb; 21(1):57-73.e7. PubMed ID: 32919863
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4. Actionable co-alterations in breast tumors with pathogenic mutations in the homologous recombination DNA damage repair pathway.
Heeke AL; Xiu J; Elliott A; Korn WM; Lynce F; Pohlmann PR; Isaacs C; Swain SM; Vidal G; Schwartzberg LS; Tan AR
Breast Cancer Res Treat; 2020 Nov; 184(2):265-275. PubMed ID: 32776290
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5. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links.
Rickman KA; Noonan RJ; Lach FP; Sridhar S; Wang AT; Abhyankar A; Huang A; Kelly M; Auerbach AD; Smogorzewska A
Genes Dev; 2020 Jun; 34(11-12):832-846. PubMed ID: 32354836
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6. Camptothecin targets wrn protein: mechanism and relevance in clinical breast cancer.
Shamanna RA; Lu H; Croteau DL; Arora A; Agarwal D; Ball G; Aleskandarany MA; Ellis IO; Pommier Y; Madhusudan S; Bohr VA
Oncotarget; 2016 Mar; 7(12):13269-84. PubMed ID: 26959889
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7. Epigenetic deregulation of DNA repair and its potential for therapy.
Hegi ME; Sciuscio D; Murat A; Levivier M; Stupp R
Clin Cancer Res; 2009 Aug; 15(16):5026-31. PubMed ID: 19671858
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8. DNA-dependent protein kinase (DNA-PK)-dependent cisplatin-induced loss of nucleolar facilitator of chromatin transcription (FACT) and regulation of cisplatin sensitivity by DNA-PK and FACT.
Dejmek J; Iglehart JD; Lazaro JB
Mol Cancer Res; 2009 Apr; 7(4):581-91. PubMed ID: 19372586
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9. Timing of adjuvant chemotherapy and tamoxifen in women with breast cancer: findings from two consecutive trials of Gruppo Oncologico Nord-Ovest-Mammella Intergruppo (GONO-MIG) Group.
Del Mastro L; Dozin B; Aitini E; Catzeddu T; Baldini E; Contu A; Durando A; Danese S; Cavazzini G; Canavese G; Bruzzi P; Pronzato P; Venturini M;
Ann Oncol; 2008 Feb; 19(2):299-307. PubMed ID: 17947224
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10. Werner syndrome helicase (wrn), nuclear DNA helicase II (NDH II) and histone gammaH2AX are localized to the centrosome.
Zhang S; Hemmerich P; Grosse F
Cell Biol Int; 2007 Oct; 31(10):1109-21. PubMed ID: 17498979
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