BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Cervical cancer AND PIK3CA, MGC142161, 5290, ENSG00000121879, P42336, MGC142163, p110-alpha, PI3K
586 results:

  • 1. Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix.
    Bellone S; Jeong K; Halle MK; Krakstad C; McNamara B; Greenman M; Mutlu L; Demirkiran C; Hartwich TMP; Yang-Hartwich Y; Zipponi M; Buza N; Hui P; Raspagliesi F; Lopez S; Paolini B; Milione M; Perrone E; Scambia G; Altwerger G; Ravaggi A; Bignotti E; Huang GS; Andikyan V; Clark M; Ratner E; Azodi M; Schwartz PE; Quick CM; Angioli R; Terranova C; Zaidi S; Nandi S; Alexandrov LB; Siegel ER; Choi J; Schlessinger J; Santin AD
    Proc Natl Acad Sci U S A; 2024 Apr; 121(17):e2321898121. PubMed ID: 38625939
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Downregulation of LAMB3 Altered the Carcinogenic Properties of Human Papillomavirus 16-Positive cervical cancer Cells.
    Wattanathavorn W; Seki M; Suzuki Y; Buranapraditkun S; Kitkumthorn N; Sasivimolrattana T; Bhattarakosol P; Chaiwongkot A
    Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38473784
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Clonal origin and genomic diversity in Lynch syndrome-associated endometrial cancer with multiple synchronous tumors: Identification of the pathogenicity of MLH1 p.L582H.
    Takahashi K; Yachida N; Tamura R; Adachi S; Kondo S; Abé T; Umezu H; Nyuzuki H; Okuda S; Nakaoka H; Yoshihara K
    Genes Chromosomes Cancer; 2024 Mar; 63(3):e23231. PubMed ID: 38459936
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Chlamydia trachomatis enhances HPV persistence through immune modulation.
    Lu Y; Wu Q; Wang L; Ji L
    BMC Infect Dis; 2024 Feb; 24(1):229. PubMed ID: 38378486
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Circular RNAs and cervical cancer: friends or foes? A landscape on circRNA-mediated regulation of key signaling pathways involved in the onset and progression of HPV-related cervical neoplasms.
    Heydarnia E; Dorostgou Z; Hedayati N; Mousavi V; Yahyazadeh S; Alimohammadi M; Gheibi M; Heidari P; Igder S; Mafi A; Vakili O
    Cell Commun Signal; 2024 Feb; 22(1):107. PubMed ID: 38341592
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Exploring a novel seven-gene marker and mitochondrial gene TMEM38A for predicting cervical cancer radiotherapy sensitivity using machine learning algorithms.
    Wang J; Mou X; Lu H; Jiang H; Xian Y; Wei X; Huang Z; Tang S; Cen H; Dong M; Liang Y; Shi G
    Front Endocrinol (Lausanne); 2023; 14():1302074. PubMed ID: 38327905
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Pterostilbene upregulates MICA/B via the pi3k/AKT signaling pathway to enhance the capability of natural killer cells to kill cervical cancer cells.
    Li Z; Zhang J; You S; Zhang J; Zhang Y; Akram Z; Sun S
    Exp Cell Res; 2024 Feb; 435(2):113933. PubMed ID: 38296018
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Integrated genomic and transcriptomic analysis reveals the activation of pi3k signaling pathway in HPV-independent cervical cancers.
    Wang Y; He M; He T; Ouyang X; Shen X; Shi W; Huang S; Xiang L; Zou D; Jiang W; Yang H
    Br J Cancer; 2024 Apr; 130(6):987-1000. PubMed ID: 38253702
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Network pharmacology combined with experimental verification to explore the potential mechanism of naringenin in the treatment of cervical cancer.
    Zhou J; Li H; Wu B; Zhu L; Huang Q; Guo Z; He Q; Wang L; Peng X; Guo T
    Sci Rep; 2024 Jan; 14(1):1860. PubMed ID: 38253629
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Whether specific genetic feature predicted immunotherapy efficacy: A case report.
    Chen J; Pang L; He L; Li T; Cheng X
    Medicine (Baltimore); 2024 Jan; 103(2):e36922. PubMed ID: 38215117
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. DHCR7 promotes lymph node metastasis in cervical cancer through cholesterol reprogramming-mediated activation of the KANK4/pi3k/AKT axis and VEGF-C secretion.
    Mei X; Xiong J; Liu J; Huang A; Zhu D; Huang Y; Wang H
    Cancer Lett; 2024 Mar; 584():216609. PubMed ID: 38211648
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. FOXM1 transcriptional regulation of RacGAP1 activates the pi3k/AKT signaling pathway to promote the proliferation, migration, and invasion of cervical cancer cells.
    Yao H; Li J; Zhou D; Pan X; Chu Y; Yin J
    Int J Clin Oncol; 2024 Mar; 29(3):333-344. PubMed ID: 38172354
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/pi3k Pathway Alterations and Advanced Solid Malignancies.
    Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
    Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The effects of HPV oncoproteins on host communication networks: Therapeutic connotations.
    Skelin J; Luk HY; Butorac D; Boon SS; Tomaić V
    J Med Virol; 2023 Dec; 95(12):e29315. PubMed ID: 38115222
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. HPV E6/E7: insights into their regulatory role and mechanism in signaling pathways in HPV-associated tumor.
    Peng Q; Wang L; Zuo L; Gao S; Jiang X; Han Y; Lin J; Peng M; Wu N; Tang Y; Tian H; Zhou Y; Liao Q
    Cancer Gene Ther; 2024 Jan; 31(1):9-17. PubMed ID: 38102462
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Comprehensive analysis of clinical prognosis and biological significance of CNIH4 in cervical cancer.
    Wang J; Wang S; Wang J; Huang J; Lu H; Pan B; Pan H; Song Y; Deng Q; Jin X; Shi G
    Cancer Med; 2023 Dec; 12(24):22381-22394. PubMed ID: 38087815
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Inhibitory actions of oxyresveratrol on the pi3k/AKT signaling cascade in cervical cancer cells.
    Tan B; Wikan N; Lin S; Thaklaewphan P; Potikanond S; Nimlamool W
    Biomed Pharmacother; 2024 Jan; 170():115982. PubMed ID: 38056236
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Design, synthesis and bioevaluation of novel prenylated chalcones derivatives as potential antitumor agents.
    Yu J; Wang X; Cheng S; Zeng X; Wan X; Wei S; Xu B; Luo H; Meng X
    Eur J Pharm Sci; 2024 Jan; 192():106660. PubMed ID: 38052256
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Molecular landscape of ERBB2/HER2 gene amplification among patients with gynecologic malignancies; clinical implications and future directions.
    Nasioudis D; Gysler S; Latif N; Cory L; Giuntoli RL; Kim SH; Simpkins F; Martin L; Ko EM
    Gynecol Oncol; 2024 Jan; 180():1-5. PubMed ID: 38029652
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. High-grade intraductal carcinoma of the parotid gland harboring CTNNA1::ALK rearrangement: Changes in genetic status using genetic testing during treatment with an ALK inhibitor.
    Watanabe T; Honma Y; Yonemori K; Sunami K; Yoshimoto S; Mori T
    Head Neck; 2024 Mar; 46(3):E26-E31. PubMed ID: 38018800
    [TBL] [Abstract] [Full Text] [Related]  


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