Terms: = Cervical cancer AND STK11, LKB1, 6794, ENSG00000118046, Q15831, PJS AND Treatment
14 results:
1. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
[TBL] [Abstract] [Full Text] [Related]
2. The differences in immune features and genomic profiling between squamous cell carcinoma and adenocarcinoma - A multi-center study in Chinese patients with uterine cervical cancer.
Li J; Xue X; Zhang Y; Ding F; Wu W; Liu C; Xu Y; Chen H; Ou Q; Shao Y; Li X; Wu F; Wu X
Gynecol Oncol; 2023 Aug; 175():133-141. PubMed ID: 37356314
[TBL] [Abstract] [Full Text] [Related]
3. Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
Wang C; Dai S; Zhao X; Zhang Y; Gong L; Fu K; Ma C; Peng C; Li Y
Biomed Pharmacother; 2023 Jul; 163():114882. PubMed ID: 37196541
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4. Efficacy and Safety of Sintilimab Plus Anlotinib for PD-L1-Positive Recurrent or Metastatic cervical cancer: A Multicenter, Single-Arm, Prospective Phase II Trial.
Xu Q; Wang J; Sun Y; Lin Y; Liu J; Zhuo Y; Huang Z; Huang S; Chen Y; Chen L; Ke M; Li L; Li Z; Pan J; Song Y; Liu R; Chen C
J Clin Oncol; 2022 Jun; 40(16):1795-1805. PubMed ID: 35192397
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5. Genomic profiling of advanced cervical cancer to predict response to programmed death-1 inhibitor combination therapy: a secondary analysis of the CLAP trial.
Huang X; He M; Peng H; Tong C; Liu Z; Zhang X; Shao Y; Zhu D; Zhang J; Yin JC; Yang F; Lan C
J Immunother Cancer; 2021 May; 9(5):. PubMed ID: 34011535
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6. Phase I Basket Study of Taselisib, an Isoform-Selective PI3K Inhibitor, in Patients with
Jhaveri K; Chang MT; Juric D; Saura C; Gambardella V; Melnyk A; Patel MR; Ribrag V; Ma CX; Aljumaily R; Bedard PL; Sachdev JC; Dunn L; Won H; Bond J; Jones S; Savage HM; Scaltriti M; Wilson TR; Wei MC; Hyman DM
Clin Cancer Res; 2021 Jan; 27(2):447-459. PubMed ID: 33148674
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7. lkb1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation.
Zulato E; Ciccarese F; Agnusdei V; Pinazza M; Nardo G; Iorio E; Curtarello M; Silic-Benussi M; Rossi E; Venturoli C; Panieri E; Santoro MM; Di Paolo V; Quintieri L; Ciminale V; Indraccolo S
Biochem Pharmacol; 2018 Oct; 156():479-490. PubMed ID: 30222967
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8. PIK3CA Pathway Mutations Predictive of Poor Response Following Standard Radiochemotherapy ± Cetuximab in cervical cancer Patients.
de la Rochefordiere A; Kamal M; Floquet A; Thomas L; Petrow P; Petit T; Pop M; Fabbro M; Kerr C; Joly F; Sevin E; Maillard S; Curé H; Weber B; Brunaud C; Minsat M; Gonzague L; Berton-Rigaud D; Aumont M; Gladieff L; Peignaux K; Bernard V; Leroy Q; Bieche I; Margogne A; Nadan A; Fourchotte V; Diallo A; Asselain B; Plancher C; Armanet S; Beuzeboc P; Scholl SM
Clin Cancer Res; 2015 Jun; 21(11):2530-7. PubMed ID: 25724520
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9. Successful pregnancy in a Peutz-Jeghers syndrome patient with lobular endocervical glandular hyperplasia.
Takei Y; Fujiwara H; Nagashima T; Takahashi Y; Takahashi S; Suzuki M
J Obstet Gynaecol Res; 2015 Mar; 41(3):468-73. PubMed ID: 25257303
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10. Metformin impairs the growth of liver kinase B1-intact cervical cancer cells.
Xiao X; He Q; Lu C; Werle KD; Zhao RX; Chen J; Davis BC; Cui R; Liang J; Xu ZX
Gynecol Oncol; 2012 Oct; 127(1):249-55. PubMed ID: 22735790
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11. Inhibition of cervical cancer cell growth through activation of upstream kinases of AMP-activated protein kinase.
Yu SY; Chan DW; Liu VW; Ngan HY
Tumour Biol; 2009; 30(2):80-5. PubMed ID: 19407487
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12. Interference with energy metabolism by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside induces HPV suppression in cervical carcinoma cells and apoptosis in the absence of lkb1.
Nafz J; De-Castro Arce J; Fleig V; Patzelt A; Mazurek S; Rösl F
Biochem J; 2007 May; 403(3):501-10. PubMed ID: 17212587
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13. Epigenetic inactivation of lkb1 in primary tumors associated with the Peutz-Jeghers syndrome.
Esteller M; Avizienyte E; Corn PG; Lothe RA; Baylin SB; Aaltonen LA; Herman JG
Oncogene; 2000 Jan; 19(1):164-8. PubMed ID: 10644993
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14. Disseminated cervical adenoma malignum and bilateral ovarian sex cord tumors with annular tubules associated with Peutz-Jeghers syndrome.
Srivatsa PJ; Keeney GL; Podratz KC
Gynecol Oncol; 1994 May; 53(2):256-64. PubMed ID: 8188091
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