Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207
3725 results:

  • 1. BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21
    Ren G; Chen J; Pu Y; Yang EJ; Tao S; Mou PK; Chen LJ; Zhu W; Chan KL; Luo G; Deng C; Shim JS
    Int J Biol Sci; 2024; 20(6):1978-1991. PubMed ID: 38617536
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. PREX2 contributes to radiation resistance by inhibiting radiotherapy-induced tumor immunogenicity via cGAS/STING/IFNs pathway in colorectal cancer.
    Li M; Xiao J; Song S; Han F; Liu H; Lin Y; Ni Y; Zeng S; Zou X; Wu J; Wang F; Xu S; Liang Y; Xu P; Hong H; Qiu J; Cao J; Zhu Q; Liang L
    BMC Med; 2024 Apr; 22(1):154. PubMed ID: 38609982
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Discovery of a novel small-molecule activator of SIRT3 that inhibits cell proliferation and migration by apoptosis and autophagy-dependent cell death pathways in colorectal cancer.
    Mou Y; Chen Y; Fan Z; Ye L; Hu B; Han B; Wang G
    Bioorg Chem; 2024 May; 146():107327. PubMed ID: 38579616
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Indoxyl sulfate contributes to colorectal cancer cell proliferation and increased EGFR expression by activating AhR and akt.
    Ichisaka Y; Yano S; Nishimura K; Niwa T; Shimizu H
    Biomed Res; 2024; 45(2):57-66. PubMed ID: 38556263
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Predictive value of immediate early response 5 like (IER5L) in the prognosis and immune checkpoint blockade therapy of non-small cell lung cancer patients.
    Wang N; Tan X; Cao S; Liu M
    Pathol Res Pract; 2024 Apr; 256():155270. PubMed ID: 38552564
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. PI3K/akt/mTOR Signaling Pathway as a Target for colorectal cancer Treatment.
    Leiphrakpam PD; Are C
    Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542151
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Timing of Surgery and Social Determinants of Health Related to Pathologic Complete Response after Total Neoadjuvant Therapy for Rectal Adenocarcinoma: Retrospective Study of National cancer Database.
    Mai M; Goldman J; Appiah D; Abdulrahman R; Kidwell J; Shi Z
    Curr Oncol; 2024 Feb; 31(3):1291-1301. PubMed ID: 38534930
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Reduced chemokine C-C motif ligand 1 expression may negatively regulate colorectal cancer progression at liver metastatic sites.
    Iwata M; Haraguchi R; Kitazawa R; Ito C; Ogawa K; Takada Y; Kitazawa S
    J Cell Mol Med; 2024 Apr; 28(7):e18193. PubMed ID: 38506205
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Prognosis significance and potential association between ALDOA and akt expression in colorectal cancer.
    Xu M; Xi S; Li H; Xia Y; Mei G; Cheng Z
    Sci Rep; 2024 Mar; 14(1):6488. PubMed ID: 38499636
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Inhibition of PI3K/akt signaling using BKM120 reduced the proliferation and migration potentials of colorectal cancer cells and enhanced cisplatin-induced cytotoxicity.
    Khameneh SC; Sari S; Razi S; Yousefi AM; Bashash D
    Mol Biol Rep; 2024 Mar; 51(1):420. PubMed ID: 38483663
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Inhibition of Multifunctional Protein p32/C1QBP Promotes Cytostatic Effects in Colon cancer Cells by Altering Mitogenic Signaling Pathways and Promoting Mitochondrial Damage.
    Egusquiza-Alvarez CA; Moreno-Londoño AP; Alvarado-Ortiz E; Ramos-Godínez MDP; Sarabia-Sánchez MA; Castañeda-Patlán MC; Robles-Flores M
    Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38473963
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Role of deubiquitinase JOSD2 in the pathogenesis of esophageal squamous cell carcinoma.
    Wang WP; Shi D; Yun D; Hu J; Wang JF; Liu J; Yang YP; Li MR; Wang JF; Kong DL
    World J Gastroenterol; 2024 Feb; 30(6):565-578. PubMed ID: 38463028
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. [LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/akt/mTOR signaling pathway].
    Tao SN; Liu XC; Wang YY; Yang H
    Zhonghua Yi Xue Za Zhi; 2024 Mar; 104(10):758-765. PubMed ID: 38462356
    [No Abstract]    [Full Text] [Related]  

  • 14. Regulation of metastatic potential by drug repurposing and mitochondrial targeting in colorectal cancer cells.
    Mathur S; Srivastava P; Srivastava A; Rai NK; Abbas S; Kumar A; Tiwari M; Sharma LK
    BMC Cancer; 2024 Mar; 24(1):323. PubMed ID: 38459456
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. mTORC2-akt signaling to PFKFB2 activates glycolysis that enhances stemness and tumorigenicity of intestinal epithelial cells.
    Li M; Wu X; Pan Y; Song M; Yang X; Xu J; Plikus MV; Lv C; Yu L; Yu Z
    FASEB J; 2024 Mar; 38(5):e23532. PubMed ID: 38451470
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Understanding the molecular mechanism responsible for developing therapeutic radiation-induced radioresistance of rectal cancer and improving the clinical outcomes of radiotherapy - A review.
    Jain SM; Nagainallur Ravichandran S; Murali Kumar M; Banerjee A; Sun-Zhang A; Zhang H; Pathak R; Sun XF; Pathak S
    Cancer Biol Ther; 2024 Dec; 25(1):2317999. PubMed ID: 38445632
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Synergistic antitumor activity between HER2 antibody-drug conjugate and chemotherapy for treating advanced colorectal cancer.
    Liu H; Zhou D; Liu D; Xu X; Zhang K; Hu R; Xiong P; Wang C; Zeng X; Wang L; Zhang S
    Cell Death Dis; 2024 Mar; 15(3):187. PubMed ID: 38443386
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Broccoli extracellular vesicles enhance the therapeutic effects and restore the chemosensitivity of 5-fluorouracil on colon cancer.
    Cao Y; Hou L; Li M; Zhang J; Wang L; Liu C; Luo T; Yan L; Zheng L
    Food Chem Toxicol; 2024 Apr; 186():114563. PubMed ID: 38442787
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. CSF1R inhibition reprograms tumor-associated macrophages to potentiate anti-PD-1 therapy efficacy against colorectal cancer.
    Lv Q; Zhang Y; Gao W; Wang J; Hu Y; Yang H; Xie Y; Lv Y; Zhang H; Wu D; Hu L; Wang J
    Pharmacol Res; 2024 Apr; 202():107126. PubMed ID: 38432446
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The Impact of cancer-Associated Fibroblasts on the Biology and Progression of colorectal Carcinomas.
    Henrich LM; Greimelmaier K; Wessolly M; Klopp NA; Mairinger E; Krause Y; Berger S; Wohlschlaeger J; Schildhaus HU; Baba HA; Mairinger FD; Borchert S
    Genes (Basel); 2024 Feb; 15(2):. PubMed ID: 38397199
    [TBL] [Abstract] [Full Text] [Related]  


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