Terms: = Colorectal cancer AND ATM, TELO1, 472, ENSG00000149311, TEL1, ATD, ATE, DKFZp781A0353, AT1, Q13315, MGC74674, ATDC, ATC, ATA AND Treatment
183 results:
1. Distinct Driver Pathway Enrichments and a High Prevalence of
Tapia-Valladares C; Valenzuela G; González E; Maureira I; Toro J; Freire M; Sepúlveda-Hermosilla G; Ampuero D; Blanco A; Gallegos I; Morales F; Erices JI; Barajas O; Ahumada M; Contreras HR; González J; Armisén R; Marcelain K
Int J Mol Sci; 2024 Apr; 25(9):. PubMed ID: 38731914
[TBL] [Abstract] [Full Text] [Related]
2. Discovery of a Meisoindigo-Derived PROTAC as the atm Degrader: Revolutionizing colorectal cancer Therapy via Synthetic Lethality with ATR Inhibitors.
Liu TT; Wang Q; Zhou Y; Ye B; Liu T; Yan L; Fan J; Xu J; Zhou Y; Xia Z; Deng X
J Med Chem; 2024 May; 67(9):7620-7634. PubMed ID: 38634707
[TBL] [Abstract] [Full Text] [Related]
3. Canonical DDR activation by EMT inducing agent 5-Fluorouracil is modulated by a cannabinoid based combinatorial approach via inducing autophagy and suppression of vimentin expression.
Mir KB; Chakraborty S; Amin T; Kumar A; Rouf War A; Nalli Y; Kumar R; Dinesh Kumar L; Ali A; Goswami A
Biochem Pharmacol; 2024 May; 223():116126. PubMed ID: 38490521
[TBL] [Abstract] [Full Text] [Related]
4. Discovery of the first ataxia telangiectasia and Rad3-related (ATR) degraders for cancer treatment.
Huang L; Shao J; Lai W; Gu H; Yang J; Shi S; Wufoyrwoth S; Song Z; Zou Y; Xu Y; Zhu Q
Eur J Med Chem; 2024 Mar; 267():116159. PubMed ID: 38325007
[TBL] [Abstract] [Full Text] [Related]
5. Colonic stent as a bridge to surgery versus emergency rection for malignant left-sided colorectal obstruction: A systematic review and meta-analysis of randomized controlled trials.
Shang R; Han X; Zeng C; Lv F; Fang R; Tian X; Ding X
Medicine (Baltimore); 2023 Dec; 102(50):e36078. PubMed ID: 38115371
[TBL] [Abstract] [Full Text] [Related]
6. Efficacy of olaparib in advanced cancers with germline or somatic mutations in BRCA1, BRCA2, CHEK2 and atm, a Belgian Precision tumor-agnostic phase II study.
Joris S; Denys H; Collignon J; Rasschaert M; T'Kint de Roodenbeke D; Duhoux FP; Canon JL; Tejpar S; Mebis J; Decoster L; Aftimos P; De Grève J
ESMO Open; 2023 Dec; 8(6):102041. PubMed ID: 37852034
[TBL] [Abstract] [Full Text] [Related]
7. TP5: A Novel Therapeutic Approach Targeting Aberrant and Hyperactive CDK5/p25 for the Treatment of colorectal Carcinoma.
Amin N; Wang H; Song Q; Bhaskar M; Yadav SP; Gilbert MR; Pant H; Tabouret E; Zhuang Z
Int J Mol Sci; 2023 Jul; 24(14):. PubMed ID: 37511490
[TBL] [Abstract] [Full Text] [Related]
8. Uncommon variants detected via hereditary cancer panel and suggestions for genetic counseling.
Özdemir Z; Çevik E; Öksüzoğlu ÖBÇ; Doğan M; Ateş Ö; Esin E; Bilgetekin İ; Demirci U; Köseoğlu Ç; Topal A; Karadurmuş N; Erdem HB; Bahsi T
Mutat Res; 2023; 827():111831. PubMed ID: 37453313
[TBL] [Abstract] [Full Text] [Related]
9. The association between prescription drugs and colorectal cancer prognosis: a nationwide cohort study using a medication-wide association study.
Woo HT; Jeong SY; Shin A
BMC Cancer; 2023 Jul; 23(1):643. PubMed ID: 37430209
[TBL] [Abstract] [Full Text] [Related]
10. Relationships Between Urinary and Nonurinary Symptoms in Treatment-Seeking Women in LURN.
Smith AR; Mansfield SA; Bradley CS; Kenton KS; Helmuth ME; Cameron AP; Kirkali Z; Bretschneider CE; Andreev V; Sarma A; Lane G; Collins SA; Cella D; Lai HH; Harte SE; Griffith JW;
Urogynecology (Phila); 2024 Feb; 30(2):123-131. PubMed ID: 37428882
[TBL] [Abstract] [Full Text] [Related]
11. Design, Synthesis, and Biological Evaluation of Potent and Selective Inhibitors of ataxia Telangiectasia Mutated and Rad3-Related (ATR) Kinase for the Efficient Treatment of cancer.
Shao J; Huang L; Lai W; Zou Y; Zhu Q
Molecules; 2023 Jun; 28(11):. PubMed ID: 37298997
[TBL] [Abstract] [Full Text] [Related]
12. Genomic landscape of locally advanced rectal adenocarcinoma: Comparison between before and after neoadjuvant chemoradiation and effects of genetic biomarkers on clinical outcomes and tumor response.
Lee TH; Jang BS; Chang JH; Kim E; Park JH; Chie EK
Cancer Med; 2023 Jul; 12(14):15664-15675. PubMed ID: 37260182
[TBL] [Abstract] [Full Text] [Related]
13. Differences in DNA damage repair gene mutations between left- and right-sided colorectal cancer.
Huang W; Li W; Xu N; Li H; Zhang Z; Zhang X; He T; Yao J; Xu M; He Q; Guo L; Zhang S
Cancer Med; 2023 May; 12(9):10187-10198. PubMed ID: 37096801
[TBL] [Abstract] [Full Text] [Related]
14. Transanal endoscopic microsurgery versus radical resection for early-stage rectal cancer: a systematic review and meta- analysis.
Li W; Xiang XX; Da Wang H; Cai CJ; Cao YH; Liu T
Int J Colorectal Dis; 2023 Feb; 38(1):49. PubMed ID: 36800079
[TBL] [Abstract] [Full Text] [Related]
15. Ellagic acid inhibits cell proliferation, migration, and invasion of anaplastic thyroid cancer cells via the Wnt/β-catenin and PI3K/Akt pathways.
Meng X; Cui Z; Shi H; Ma X; Li W; Liu X; Jiang Y
Acta Biochim Pol; 2023 Feb; 70(1):109-115. PubMed ID: 36773307
[TBL] [Abstract] [Full Text] [Related]
16. Fistula-Associated Anal Adenocarcinoma: A 20-Year Single-Center Experience.
Harpain F; Dawoud C; Wimmer K; Schlager L; Kirchnawy S; Rizk D; Girgis K; Mittermair E; Oberndorfer F; Wöran K; Riss S; Stift A; Stift J
Ann Surg Oncol; 2023 Jun; 30(6):3517-3527. PubMed ID: 36757514
[TBL] [Abstract] [Full Text] [Related]
17. Germline cancer Gene Expression Quantitative Trait Loci Are Associated with Local and Global Tumor Mutations.
Liu Y; Gusev A; Kraft P
Cancer Res; 2023 Apr; 83(8):1191-1202. PubMed ID: 36745477
[TBL] [Abstract] [Full Text] [Related]
18. Construction and validation of a novel Ferroptosis-related gene signature predictive model in rectal cancer.
Shi WK; Liu YX; Qiu XY; Zhou JY; Zhou JL; Lin GL
BMC Genomics; 2022 Nov; 23(1):764. PubMed ID: 36414988
[TBL] [Abstract] [Full Text] [Related]
19. The first comprehensive genomic characterization of rectal squamous cell carcinoma.
Astaras C; De Vito C; Chaskar P; Bornand A; Khanfir K; Sciarra A; Letovanec I; Corro C; Dietrich PY; Tsantoulis P; Koessler T
J Gastroenterol; 2023 Feb; 58(2):125-134. PubMed ID: 36357817
[TBL] [Abstract] [Full Text] [Related]
20. atm kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancer.
Davis SL; Hartman SJ; Bagby SM; Schlaepfer M; Yacob BW; Tse T; Simmons DM; Diamond JR; Lieu CH; Leal AD; Cadogan EB; Hughes GD; Durant ST; Messersmith WA; Pitts TM
BMC Cancer; 2022 Oct; 22(1):1107. PubMed ID: 36309653
[TBL] [Abstract] [Full Text] [Related]
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