Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND ATR, Q13535, 545, ENSG00000175054, MEC1, SCKL, SCKL1, FRP1 AND Treatment
106 results:

  • 1. Ataxia telangiectasia and Rad3-related (atr) inhibition by VE-822 potently reversed 5-flourouracil resistance in colorectal cancer cells through targeting DNA damage response.
    Mihanfar A; Asghari F; Majidinia M
    Mol Biol Rep; 2024 Mar; 51(1):474. PubMed ID: 38553623
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Discovery of the first ataxia telangiectasia and Rad3-related (atr) degraders for cancer treatment.
    Huang L; Shao J; Lai W; Gu H; Yang J; Shi S; Wufoyrwoth S; Song Z; Zou Y; Xu Y; Zhu Q
    Eur J Med Chem; 2024 Mar; 267():116159. PubMed ID: 38325007
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Practice Patterns for Organ Preservation in US Patients With Rectal cancer, 2006-2020.
    Loria A; Tejani MA; Temple LK; Justiniano CF; Melucci AD; Becerra AZ; Monson JRT; Aquina CT; Fleming FJ
    JAMA Oncol; 2024 Jan; 10(1):79-86. PubMed ID: 37943566
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Interaction analysis of high-risk pathological features on adjuvant chemotherapy survival benefit in stage II colon cancer patients: a multi-center, retrospective study.
    Li K; Zhao F; Guo Y; Wu Q; Luo S; Zhang J; Li H; Hu S; Wu B; Lin G; Qiu H; Niu B; Sun X; Xu L; Lu J; Du X; Wang Z; Wang X; Kang L; Wang Z; Wang Q; Liu Q; Xiao Y
    BMC Cancer; 2023 Sep; 23(1):797. PubMed ID: 37718392
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Analysis of Quinolinequinone Analogs with Promising Cytotoxic Activity against Breast cancer.
    Yilmaz Goler AM; Tarbin Jannuzzi A; Biswas A; Mondal S; Basavanakatti VN; Jayaprakash Venkatesan R; Yıldırım H; Yıldız M; Çelik Onar H; Bayrak N; Jayaprakash V; TuYuN AF
    Chem Biodivers; 2023 Sep; 20(9):e202300848. PubMed ID: 37590495
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Stoma-free Survival After Rectal cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
    Greijdanus NG; Wienholts K; Ubels S; Talboom K; Hannink G; Wolthuis A; de Lacy FB; Lefevre JH; Solomon M; Frasson M; Rotholtz N; Denost Q; Perez RO; Konishi T; Panis Y; Rutegård M; Hompes R; Rosman C; van Workum F; Tanis PJ; de Wilt JHW;
    Ann Surg; 2023 Nov; 278(5):772-780. PubMed ID: 37498208
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Relationships Between Urinary and Nonurinary Symptoms in treatment-Seeking Women in LURN.
    Smith AR; Mansfield SA; Bradley CS; Kenton KS; Helmuth ME; Cameron AP; Kirkali Z; Bretschneider CE; Andreev V; Sarma A; Lane G; Collins SA; Cella D; Lai HH; Harte SE; Griffith JW;
    Urogynecology (Phila); 2024 Feb; 30(2):123-131. PubMed ID: 37428882
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Design, Synthesis, and Biological Evaluation of Potent and Selective Inhibitors of Ataxia Telangiectasia Mutated and Rad3-Related (atr) Kinase for the Efficient treatment of cancer.
    Shao J; Huang L; Lai W; Zou Y; Zhu Q
    Molecules; 2023 Jun; 28(11):. PubMed ID: 37298997
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. ATF2 loss promotes 5-FU resistance in colon cancer cells via activation of the atr-Chk1 damage response pathway.
    Yang H; Huebner K; Hampel C; Erlenbach-Wuensch K; Selvamani SB; Shukla V; Geppert CI; Hartmann A; Mahadevan V; Schneider-Stock R
    BMC Cancer; 2023 May; 23(1):480. PubMed ID: 37237279
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Combining radiation and the atr inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer.
    Liu C; Wang X; Qin W; Tu J; Li C; Zhao W; Ma L; Liu B; Qiu H; Yuan X
    Cancer Commun (Lond); 2023 Apr; 43(4):435-454. PubMed ID: 36855844
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. CT-based radiomics for the identification of colorectal cancer liver metastases sensitive to first-line irinotecan-based chemotherapy.
    Qi W; Yang J; Zheng L; Lu Y; Liu R; Ju Y; Niu T; Wang D
    Med Phys; 2023 May; 50(5):2705-2714. PubMed ID: 36841949
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Chloroquine prevents hypoxic accumulation of HIF-1α by inhibiting atr kinase: implication in chloroquine-mediated chemosensitization of colon carcinoma cells under hypoxia.
    Kang C; Ju S; Kim J; Jung Y
    Pharmacol Rep; 2023 Feb; 75(1):211-221. PubMed ID: 36508076
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. One-Drop Serum Screening Test for Anal cancer in Men via Infrared Attenuated Total Reflection Spectroscopy.
    Alcántara-Quintana LE; López-Mendoza CM; Rodríguez-Aguilar M; Medellín-Castillo N; Mizaikoff B; Flores-Ramírez R; Galván-Romero VS; Díaz de León-Martínez L
    Anal Chem; 2022 Nov; 94(44):15250-15260. PubMed ID: 36197692
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Safety and Efficacy of Programmed Cell Death 1 and Programmed Death Ligand-1 Inhibitors in the treatment of cancer: An Overview of Systematic Reviews.
    Ou SL; Luo J; Wei H; Qin XL; Du SY; Wang S; Jiang Q
    Front Immunol; 2022; 13():953761. PubMed ID: 35911744
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. cancer Risk C (CR-C), a functional genomics test is a sensitive and rapid test for germline mismatch repair deficiency.
    Alim I; Loke J; Yam S; Templeton AS; Newcomb P; Lindor NM; Pai RK; Jenkins MA; Buchanan DD; Gallinger S; Klugman S; Ostrer H
    Genet Med; 2022 Sep; 24(9):1821-1830. PubMed ID: 35616648
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Shikonin induces cell autophagy via modulating the microRNA -545-3p/guanine nucleotide binding protein beta polypeptide 1 axis, thereby disrupting cellular carcinogenesis in colon cancer.
    Hu Z; Zhou X; Zeng D; Lai J
    Bioengineered; 2022 Mar; 13(3):5928-5941. PubMed ID: 35192430
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. miR-545 promotes colorectal cancer by inhibiting transferring in the non-normal ferroptosis signaling.
    Zheng S; Hu L; Song Q; Shan Y; Yin G; Zhu H; Kong W; Zhou C
    Aging (Albany NY); 2021 Dec; 13(24):26137-26147. PubMed ID: 34954694
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Risk factors for developing peritoneal metastases after curative surgery for colorectal cancer: A systematic review and meta-analysis.
    Zhang Y; Qin X; Chen W; Liu D; Luo J; Wang H; Wang H
    Colorectal Dis; 2021 Nov; 23(11):2846-2858. PubMed ID: 34411399
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. WEE1 inhibitor and ataxia telangiectasia and RAD3-related inhibitor trigger stimulator of interferon gene-dependent immune response and enhance tumor treatment efficacy through programmed death-ligand 1 blockade.
    Wu X; Kang X; Zhang X; Xie W; Su Y; Liu X; Guo L; Guo E; Li F; Hu D; Qin X; Fu Y; Peng W; Jia J; Wang C
    Cancer Sci; 2021 Nov; 112(11):4444-4456. PubMed ID: 34382294
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Bavachinin Induces G2/M Cell Cycle Arrest and Apoptosis via the ATM/atr Signaling Pathway in Human Small Cell Lung cancer and Shows an Antitumor Effect in the Xenograft Model.
    Hung SY; Lin SC; Wang S; Chang TJ; Tung YT; Lin CC; Ho CT; Li S
    J Agric Food Chem; 2021 Jun; 69(22):6260-6270. PubMed ID: 34043345
    [TBL] [Abstract] [Full Text] [Related]  


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