Terms: = Colorectal cancer AND ATR, Q13535, 545, ENSG00000175054, MEC1, SCKL, SCKL1, FRP1 AND Treatment
110 results:
1. LncRNA HOTAIR promotes DNA damage repair and radioresistance by targeting atr in colorectal cancer.
Hu H; Yang H; Fan S; Jia X; Zhao Y; Li H
Oncol Res; 2024; 32(8):1335-1346. PubMed ID: 39055884
[TBL] [Abstract] [Full Text] [Related]
2. Development, Optimization, and in vitro Evaluation of Silybin-loaded PLGA Nanoparticles and Decoration with 5TR1 Aptamer for Targeted Delivery to colorectal cancer Cells.
Rahimnia SM; Saeedi M; Akbari J; Morteza-Semnani K; Hedayatizadeh-Omran A; Yazdian-Robati R
AAPS PharmSciTech; 2024 Jun; 25(6):141. PubMed ID: 38898204
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3. Downregulation of circ-RAPGEF5 inhibits colorectal cancer progression by reducing the expression of polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3).
Cheng D; Chu F; Liang F; Zhang N; Wang J; Yue W
Environ Toxicol; 2024 Aug; 39(8):4249-4260. PubMed ID: 38775215
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4. Discovery of a Meisoindigo-Derived PROTAC as the ATM Degrader: Revolutionizing colorectal cancer Therapy via Synthetic Lethality with atr Inhibitors.
Liu TT; Wang Q; Zhou Y; Ye B; Liu T; Yan L; Fan J; Xu J; Zhou Y; Xia Z; Deng X
J Med Chem; 2024 May; 67(9):7620-7634. PubMed ID: 38634707
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5. Ataxia telangiectasia and Rad3-related (atr) inhibition by VE-822 potently reversed 5-flourouracil resistance in colorectal cancer cells through targeting DNA damage response.
Mihanfar A; Asghari F; Majidinia M
Mol Biol Rep; 2024 Mar; 51(1):474. PubMed ID: 38553623
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6. Discovery of the first ataxia telangiectasia and Rad3-related (atr) degraders for cancer treatment.
Huang L; Shao J; Lai W; Gu H; Yang J; Shi S; Wufoyrwoth S; Song Z; Zou Y; Xu Y; Zhu Q
Eur J Med Chem; 2024 Mar; 267():116159. PubMed ID: 38325007
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7. Practice Patterns for Organ Preservation in US Patients With Rectal cancer, 2006-2020.
Loria A; Tejani MA; Temple LK; Justiniano CF; Melucci AD; Becerra AZ; Monson JRT; Aquina CT; Fleming FJ
JAMA Oncol; 2024 Jan; 10(1):79-86. PubMed ID: 37943566
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8. Interaction analysis of high-risk pathological features on adjuvant chemotherapy survival benefit in stage II colon cancer patients: a multi-center, retrospective study.
Li K; Zhao F; Guo Y; Wu Q; Luo S; Zhang J; Li H; Hu S; Wu B; Lin G; Qiu H; Niu B; Sun X; Xu L; Lu J; Du X; Wang Z; Wang X; Kang L; Wang Z; Wang Q; Liu Q; Xiao Y
BMC Cancer; 2023 Sep; 23(1):797. PubMed ID: 37718392
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9. Analysis of Quinolinequinone Analogs with Promising Cytotoxic Activity against Breast cancer.
Yilmaz Goler AM; Tarbin Jannuzzi A; Biswas A; Mondal S; Basavanakatti VN; Jayaprakash Venkatesan R; Yıldırım H; Yıldız M; Çelik Onar H; Bayrak N; Jayaprakash V; TuYuN AF
Chem Biodivers; 2023 Sep; 20(9):e202300848. PubMed ID: 37590495
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10. Stoma-free Survival After Rectal cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
Greijdanus NG; Wienholts K; Ubels S; Talboom K; Hannink G; Wolthuis A; de Lacy FB; Lefevre JH; Solomon M; Frasson M; Rotholtz N; Denost Q; Perez RO; Konishi T; Panis Y; Rutegård M; Hompes R; Rosman C; van Workum F; Tanis PJ; de Wilt JHW;
Ann Surg; 2023 Nov; 278(5):772-780. PubMed ID: 37498208
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11. Relationships Between Urinary and Nonurinary Symptoms in treatment-Seeking Women in LURN.
Smith AR; Mansfield SA; Bradley CS; Kenton KS; Helmuth ME; Cameron AP; Kirkali Z; Bretschneider CE; Andreev V; Sarma A; Lane G; Collins SA; Cella D; Lai HH; Harte SE; Griffith JW;
Urogynecology (Phila); 2024 Feb; 30(2):123-131. PubMed ID: 37428882
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12. Design, Synthesis, and Biological Evaluation of Potent and Selective Inhibitors of Ataxia Telangiectasia Mutated and Rad3-Related (atr) Kinase for the Efficient treatment of cancer.
Shao J; Huang L; Lai W; Zou Y; Zhu Q
Molecules; 2023 Jun; 28(11):. PubMed ID: 37298997
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13. ATF2 loss promotes 5-FU resistance in colon cancer cells via activation of the atr-Chk1 damage response pathway.
Yang H; Huebner K; Hampel C; Erlenbach-Wuensch K; Selvamani SB; Shukla V; Geppert CI; Hartmann A; Mahadevan V; Schneider-Stock R
BMC Cancer; 2023 May; 23(1):480. PubMed ID: 37237279
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14. Combining radiation and the atr inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer.
Liu C; Wang X; Qin W; Tu J; Li C; Zhao W; Ma L; Liu B; Qiu H; Yuan X
Cancer Commun (Lond); 2023 Apr; 43(4):435-454. PubMed ID: 36855844
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15. CT-based radiomics for the identification of colorectal cancer liver metastases sensitive to first-line irinotecan-based chemotherapy.
Qi W; Yang J; Zheng L; Lu Y; Liu R; Ju Y; Niu T; Wang D
Med Phys; 2023 May; 50(5):2705-2714. PubMed ID: 36841949
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16. Chloroquine prevents hypoxic accumulation of HIF-1α by inhibiting atr kinase: implication in chloroquine-mediated chemosensitization of colon carcinoma cells under hypoxia.
Kang C; Ju S; Kim J; Jung Y
Pharmacol Rep; 2023 Feb; 75(1):211-221. PubMed ID: 36508076
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17. One-Drop Serum Screening Test for Anal cancer in Men via Infrared Attenuated Total Reflection Spectroscopy.
Alcántara-Quintana LE; López-Mendoza CM; Rodríguez-Aguilar M; Medellín-Castillo N; Mizaikoff B; Flores-Ramírez R; Galván-Romero VS; Díaz de León-Martínez L
Anal Chem; 2022 Nov; 94(44):15250-15260. PubMed ID: 36197692
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18. Safety and Efficacy of Programmed Cell Death 1 and Programmed Death Ligand-1 Inhibitors in the treatment of cancer: An Overview of Systematic Reviews.
Ou SL; Luo J; Wei H; Qin XL; Du SY; Wang S; Jiang Q
Front Immunol; 2022; 13():953761. PubMed ID: 35911744
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19. cancer Risk C (CR-C), a functional genomics test is a sensitive and rapid test for germline mismatch repair deficiency.
Alim I; Loke J; Yam S; Templeton AS; Newcomb P; Lindor NM; Pai RK; Jenkins MA; Buchanan DD; Gallinger S; Klugman S; Ostrer H
Genet Med; 2022 Sep; 24(9):1821-1830. PubMed ID: 35616648
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20. Shikonin induces cell autophagy via modulating the microRNA -545-3p/guanine nucleotide binding protein beta polypeptide 1 axis, thereby disrupting cellular carcinogenesis in colon cancer.
Hu Z; Zhou X; Zeng D; Lai J
Bioengineered; 2022 Mar; 13(3):5928-5941. PubMed ID: 35192430
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