Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND BCL9L, BCL9-2, 283149, ENSG00000186174, DLNB11
18 results:

  • 1. β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon cancer.
    Suzuki T; Kilbey A; Casa-Rodríguez N; Lawlor A; Georgakopoulou A; Hayman H; Yin Swe KL; Nordin A; Cantù C; Vantourout P; Ridgway RA; Byrne RM; Chen L; Verzi MP; Gay DM; Gil Vázquez E; Belnoue-Davis HL; Gilroy K; Køstner AH; Kersten C; Thuwajit C; Andersen DK; Wiesheu R; Jandke A; Blyth K; Roseweir AK; Leedham SJ; Dunne PD; Edwards J; Hayday A; Sansom OJ; Coffelt SB
    Cancer Immunol Res; 2023 Aug; 11(8):1137-1155. PubMed ID: 37309673
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Upregulation of miR-22-3p contributes to plumbagin-mediated inhibition of Wnt signaling in human colorectal cancer cells.
    Yadav P; Sharma P; Chetlangia N; Mayalagu P; Karunagaran D
    Chem Biol Interact; 2022 Dec; 368():110224. PubMed ID: 36272469
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Whole exome sequencing of a gut-associated lymphoid tissue neoplasm points to precursor or early form of sporadic colon carcinoma.
    Yaseen A; Ladenheim A; Olson KA; Libertini SJ; McPherson JD; Matsukuma K
    Pathol Res Pract; 2021 Apr; 220():153406. PubMed ID: 33740545
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Vitamin K3 (menadione) suppresses epithelial-mesenchymal-transition and Wnt signaling pathway in human colorectal cancer cells.
    Kishore C; Sundaram S; Karunagaran D
    Chem Biol Interact; 2019 Aug; 309():108725. PubMed ID: 31238027
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. miR-22 and miR-214 targeting bcl9l inhibit proliferation, metastasis, and epithelial-mesenchymal transition by down-regulating Wnt signaling in colon cancer.
    Sun R; Liu Z; Han L; Yang Y; Wu F; Jiang Q; Zhang H; Ma R; Miao J; He K; Wang X; Zhou D; Huang C
    FASEB J; 2019 Apr; 33(4):5411-5424. PubMed ID: 30698996
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans.
    Xicola RM; Manojlovic Z; Augustus GJ; Kupfer SS; Emmadi R; Alagiozian-Angelova V; Triche T; Salhia B; Carpten J; Llor X; Ellis NA
    Carcinogenesis; 2018 Dec; 39(11):1331-1341. PubMed ID: 30239619
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review).
    Katoh M
    Int J Mol Med; 2018 Aug; 42(2):713-725. PubMed ID: 29786110
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. bcl9l Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in colorectal cancer.
    López-García C; Sansregret L; Domingo E; McGranahan N; Hobor S; Birkbak NJ; Horswell S; Grönroos E; Favero F; Rowan AJ; Matthews N; Begum S; Phillimore B; Burrell R; Oukrif D; Spencer-Dene B; Kovac M; Stamp G; Stewart A; Danielsen H; Novelli M; Tomlinson I; Swanton C
    Cancer Cell; 2017 Jan; 31(1):79-93. PubMed ID: 28073006
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Single-walled carbon nanotubes functionalized with aptamer and piperazine-polyethylenimine derivative for targeted siRNA delivery into breast cancer cells.
    Mohammadi M; Salmasi Z; Hashemi M; Mosaffa F; Abnous K; Ramezani M
    Int J Pharm; 2015 May; 485(1-2):50-60. PubMed ID: 25712164
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. MiR-29b downregulates canonical Wnt signaling by suppressing coactivators of β-catenin in human colorectal cancer cells.
    Subramanian M; Rao SR; Thacker P; Chatterjee S; Karunagaran D
    J Cell Biochem; 2014 Nov; 115(11):1974-84. PubMed ID: 24913975
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Plumbagin downregulates Wnt signaling independent of p53 in human colorectal cancer cells.
    Raghu D; Karunagaran D
    J Nat Prod; 2014 May; 77(5):1130-4. PubMed ID: 24828199
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. LEF1 and B9L shield β-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors.
    de la Roche M; Ibrahim AE; Mieszczanek J; Bienz M
    Cancer Res; 2014 Mar; 74(5):1495-505. PubMed ID: 24419084
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. bcl9-2 promotes early stages of intestinal tumor progression.
    Brembeck FH; Wiese M; Zatula N; Grigoryan T; Dai Y; Fritzmann J; Birchmeier W
    Gastroenterology; 2011 Oct; 141(4):1359-70, 1370.e1-3. PubMed ID: 21703997
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
    Fritzmann J; Morkel M; Besser D; Budczies J; Kosel F; Brembeck FH; Stein U; Fichtner I; Schlag PM; Birchmeier W
    Gastroenterology; 2009 Jul; 137(1):165-75. PubMed ID: 19328798
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.
    de la Roche M; Worm J; Bienz M
    BMC Cancer; 2008 Jul; 8():199. PubMed ID: 18627596
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Immunohistochemical expression of the beta-catenin-interacting protein B9L is associated with histological high nuclear grade and immunohistochemical ErbB2/HER-2 expression in breast cancers.
    Toya H; Oyama T; Ohwada S; Togo N; Sakamoto I; Horiguchi J; Koibuchi Y; Adachi S; Jigami T; Nakajima T; Akiyama T
    Cancer Sci; 2007 Apr; 98(4):484-90. PubMed ID: 17309600
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. bcl9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling.
    Hoffmans R; Basler K
    Mech Dev; 2007 Jan; 124(1):59-67. PubMed ID: 17113272
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades.
    Katoh M; Katoh M
    Cancer Biol Ther; 2006 Sep; 5(9):1059-64. PubMed ID: 16940750
    [TBL] [Abstract] [Full Text] [Related]  

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