Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND CDKN2A, CDK4I, 1029, ENSG00000147889, P42771, p14, CMM2, ARF, TP16, p16, MTS1, p19, p16INK4a, INK4a, CDKN2, p16INK4, p14ARF, MLM, INK4 AND Treatment
213 results:

  • 1. Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation.
    Zhang D; Zhang JW; Xu H; Chen X; Gao Y; Jiang HG; Wang Y; Wu H; Yang L; Wang WB; Dai J; Xia L; Peng J; Zhou FX
    Mol Cancer; 2024 Apr; 23(1):70. PubMed ID: 38576002
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques.
    Deycmar S; Johnson BJ; Ray K; Schaaf GW; Ryan DP; Cullin C; Dozier BL; Ferguson B; Bimber BN; Olson JD; Caudell DL; Whitlow CT; Solingapuram Sai KK; Romero EC; Villinger FJ; Burgos AG; Ainsworth HC; Miller LD; Hawkins GA; Chou JW; Gomes B; Hettich M; Ceppi M; Charo J; Cline JM
    J Transl Med; 2024 Mar; 22(1):292. PubMed ID: 38504345
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Villosol reverses 5-FU resistance in colorectal cancer by inhibiting the cdkn2a gene regulated TP53-PI3K/Akt signaling axis.
    Chen H; Deng J; Hou TW; Shan YQ
    J Ethnopharmacol; 2024 May; 325():117907. PubMed ID: 38342156
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Safety, feasibility, and short-term-outcome of anal endoscopic submucosal dissection for anal intraepithelial neoplasia: an option for focal lesions?
    Singhartinger F; Gantschnigg A; Holzinger J; Wagner A; Singhartinger J; Koch O; Emmanuel K; Presl J
    Tech Coloproctol; 2023 Dec; 28(1):18. PubMed ID: 38102514
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Integrative analysis of single-cell and bulk RNA seq to reveal the prognostic model and tumor microenvironment remodeling mechanisms of cuproptosis-related genes in colorectal cancer.
    Chu B; Wang Y; Yang J; Dong B
    Aging (Albany NY); 2023 Dec; 15(23):14422-14444. PubMed ID: 38078879
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. High expression of cdkn2a is associated with poor prognosis in colorectal cancer and may guide PD-1-mediated immunotherapy.
    Dong Y; Zheng M; Wang X; Yu C; Qin T; Shen X
    BMC Cancer; 2023 Nov; 23(1):1097. PubMed ID: 37950153
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Increased Incidence of Liver Metastases in colorectal
    Garrett C; Cristaudo A; Barat S; Morris DL
    Anticancer Res; 2023 Oct; 43(10):4657-4662. PubMed ID: 37772565
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  • 8. Peficitinib ameliorates 5-fluorouracil-induced intestinal damage by inhibiting aging, inflammatory factors and oxidative stress.
    He S; Xia J; Jia H; Dai Q; Chen C; Zhou Y; Wang XB
    Int Immunopharmacol; 2023 Oct; 123():110753. PubMed ID: 37572505
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Construction and validation of a prognostic model for colon adenocarcinoma based on bile acid metabolism-related genes.
    Luo Q; Zhou P; Chang S; Huang Z; Zeng X
    Sci Rep; 2023 Aug; 13(1):12728. PubMed ID: 37543674
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  • 10. PTPN9 dephosphorylates FGFR2 pY656/657 through interaction with ACAP1 and ameliorates pemigatinib effect in cholangiocarcinoma.
    Zhao L; Liu J; Li K; Zhang C; Chen T; Liu Z; Tang Y; Hu X; Shi A; Shu L; Huang S; Lian S; Zhang M; Li H; Sun J; Yu X; Zhang Z; Zhang Z; Xu Y
    Hepatology; 2024 Apr; 79(4):798-812. PubMed ID: 37505213
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Mirikizumab as Induction and Maintenance Therapy for Ulcerative Colitis.
    D'Haens G; Dubinsky M; Kobayashi T; Irving PM; Howaldt S; Pokrotnieks J; Krueger K; Laskowski J; Li X; Lissoos T; Milata J; Morris N; Arora V; Milch C; Sandborn W; Sands BE;
    N Engl J Med; 2023 Jun; 388(26):2444-2455. PubMed ID: 37379135
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Atorvastatin calcium alleviates 5-fluorouracil-induced intestinal damage by inhibiting cellular senescence and significantly enhances its antitumor efficacy.
    Xia J; He S; Dai Q; Jia H; Ge Y; Zhou M; Wang X
    Int Immunopharmacol; 2023 Aug; 121():110465. PubMed ID: 37336074
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Comprehensive analyses of cuproptosis-related gene cdkn2a on prognosis and immunologic therapy in human tumors.
    Zhang D; Wang T; Zhou Y; Zhang X
    Medicine (Baltimore); 2023 Apr; 102(14):e33468. PubMed ID: 37026918
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Temporal increase in the incidence of anal squamous cell carcinoma in Kentucky and factors associated with adverse outcomes.
    O'brien SJ; Gaskins JT; Ellis CT; Martin BA; Mcdowell J; Gondim DD; Galandiuk S
    Cancer Med; 2023 May; 12(10):11462-11474. PubMed ID: 36991580
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. HPV virus and biomarkers of resistance to chemoradiation in circulating tumor cells from patients with squamous cell carcinoma of the anus.
    Ruano APC; de Jesus Ferreira Costa D; Braun AC; Torres JA; Barbosa PHP; Abdallah EA; Barberan C; Souza E Silva V; Bovolim G; Buim MEC; da Silva Alves V; Riechelmann RP; Chinen LTD
    Pathol Res Pract; 2023 Mar; 243():154327. PubMed ID: 36731178
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Cortical Parvalbumin-Positive Interneuron Development and Function Are Altered in the APC Conditional Knockout Mouse Model of Infantile and Epileptic Spasms Syndrome.
    Ryner RF; Derera ID; Armbruster M; Kansara A; Sommer ME; Pirone A; Noubary F; Jacob M; Dulla CG
    J Neurosci; 2023 Feb; 43(8):1422-1440. PubMed ID: 36717229
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Radiomics based on preoperative rectal cancer MRI to predict the metachronous liver metastasis.
    Li ZF; Kang LQ; Liu FH; Zhao M; Guo SY; Lu S; Quan S
    Abdom Radiol (NY); 2023 Mar; 48(3):833-843. PubMed ID: 36529807
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Targeting arf1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance.
    Hu HF; Gao GB; He X; Li YY; Li YJ; Li B; Pan Y; Wang Y; He QY
    J Adv Res; 2023 Sep; 51():135-147. PubMed ID: 36396045
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Clinical efficacy of sequential treatments in KRASG12C-mutant metastatic colorectal cancer: findings from a real-life multicenter Italian study (CRC-KR GOIM).
    Ciardiello D; Chiarazzo C; Famiglietti V; Damato A; Pinto C; Zampino MG; Castellano G; Gervaso L; Zaniboni A; Oneda E; Rapisardi S; Bordonaro R; Zichi C; De Vita F; Di Maio M; Parisi A; Giampieri R; Berardi R; Lavacchi D; Antonuzzo L; Tamburini E; Maiorano BA; Parrella P; Latiano TP; Normanno N; De Stefano A; Avallone A; Martini G; Napolitano S; Troiani T; Martinelli E; Ciardiello F; De Vita F; Maiello E
    ESMO Open; 2022 Oct; 7(5):100567. PubMed ID: 35994791
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. DNA Methylation Analysis to predict Regression of high-grade anal Intraepithelial Neoplasia in HIV+ men (MARINE): a cohort study protocol.
    Dias Gonçalves Lima F; van der Zee RP; Dick S; van Noesel CJM; Berkhof J; Schim van der Loeff MF; Prins JM; Steenbergen RDM; de Vries HJC
    BMJ Open; 2022 Aug; 12(8):e060301. PubMed ID: 35922105
    [TBL] [Abstract] [Full Text] [Related]  


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