BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND EGFR, mENA, 1956, ENSG00000146648, P00533, ERBB1, ERBB
4346 results:

  • 1. DB-1310, an ADC comprised of a novel anti-HER3 antibody conjugated to a DNA topoisomerase I inhibitor, is highly effective for the treatment of HER3-positive solid tumors.
    Li X; Yao J; Qu C; Luo L; Li B; Zhang Y; Zhu Z; Qiu Y; Hua H
    J Transl Med; 2024 Apr; 22(1):362. PubMed ID: 38632563
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. A phenotypic screening approach to target p60AmotL2-expressing invasive cancer cells.
    Fonseca P; Cui W; Struyf N; Tong L; Chaurasiya A; Casagrande F; Zhao H; Fernando D; Chen X; Tobin NP; Seashore-Ludlow B; Lundqvist A; Hartman J; Göndör A; Östling P; Holmgren L
    J Exp Clin Cancer Res; 2024 Apr; 43(1):107. PubMed ID: 38594748
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Anti-egfr Rechallenge in Patients With Refractory ctDNA RAS/BRAF wt Metastatic colorectal cancer: A Nonrandomized Controlled Trial.
    Ciardiello D; Martinelli E; Troiani T; Mauri G; Rossini D; Martini G; Napolitano S; Famiglietti V; Del Tufo S; Masi G; Santini D; Avallone A; Pietrantonio F; Lonardi S; Di Maio M; Zampino MG; Fazio N; Bardelli A; Siena S; Cremolini C; Sartore-Bianchi A; Ciardiello F
    JAMA Netw Open; 2024 Apr; 7(4):e245635. PubMed ID: 38592721
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Switching from FOLFIRI plus cetuximab to FOLFIRI plus bevacizumab based on early tumor shrinkage in RAS wild-type metastatic colorectal cancer: A phase II trial (HYBRID).
    Arai H; Tsuda T; Sunakawa Y; Shimokawa M; Akiyoshi K; Tokunaga S; Shoji H; Kunieda K; Kotaka M; Matsumoto T; Nagata Y; Mizukami T; Mizuki F; Danenberg KD; Boku N; Nakajima TE
    Cancer Med; 2024 Apr; 13(7):e7107. PubMed ID: 38591098
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Indoxyl sulfate contributes to colorectal cancer cell proliferation and increased egfr expression by activating AhR and Akt.
    Ichisaka Y; Yano S; Nishimura K; Niwa T; Shimizu H
    Biomed Res; 2024; 45(2):57-66. PubMed ID: 38556263
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Unveiling Prognostic RNA Biomarkers through a Multi-Cohort Study in colorectal cancer.
    Kim Z; Lee J; Yoon YE; Yun JW
    Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542291
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Targeting
    Ros J; Vaghi C; Baraibar I; Saoudi González N; Rodríguez-Castells M; García A; Alcaraz A; Salva F; Tabernero J; Elez E
    Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542278
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Dynamic ctDNA-based analysis of drug-resistant gene alterations at RAS/BRAF wild-type metastatic colorectal cancer patients after cetuximab plus chemotherapy as the first-line treatment.
    Zhou YW; Zhao X; Ni L; Cao P; Leng WB; Zhu Q; Gou HF; Zhang J; Li XF; Qiu M
    Int Immunopharmacol; 2024 Apr; 131():111887. PubMed ID: 38503018
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. [History and Perspective of Chemotherapy in Advanced Esophageal cancer].
    Shiraishi K; Kato K
    Gan To Kagaku Ryoho; 2024 Mar; 51(3):240-244. PubMed ID: 38494800
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Integrative multi-omics characterization reveals sex differences in glioblastoma.
    Jang B; Yoon D; Lee JY; Kim J; Hong J; Koo H; Sa JK
    Biol Sex Differ; 2024 Mar; 15(1):23. PubMed ID: 38491408
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Epidermal growth factor receptor (egfr) is a target of the tumor-suppressor E3 ligase FBXW7.
    Boretto M; Geurts MH; Gandhi S; Ma Z; Staliarova N; Celotti M; Lim S; He GW; Millen R; Driehuis E; Begthel H; Smabers L; Roodhart J; van Es J; Wu W; Clevers H
    Proc Natl Acad Sci U S A; 2024 Mar; 121(12):e2309902121. PubMed ID: 38483988
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Inhibition of the AURKA/YAP1 axis is a promising therapeutic option for overcoming cetuximab resistance in colorectal cancer stem cells.
    Rio-Vilariño A; Cenigaonandia-Campillo A; García-Bautista A; Mateos-Gómez PA; Schlaepfer MI; Del Puerto-Nevado L; Aguilera O; García-García L; Galeano C; de Miguel I; Serrano-López J; Baños N; Fernández-Aceñero MJ; Lacal JC; Medico E; García-Foncillas J; Cebrián A
    Br J Cancer; 2024 May; 130(8):1402-1413. PubMed ID: 38467828
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Concurrent NRAS-BRAF variants in metastatic colorectal cancer: a Tunisian case report.
    Douik H; Sahraoui G; Jemaà M; Doghri R; Charfi L; Mrad K
    Anticancer Drugs; 2024 Jun; 35(5):462-465. PubMed ID: 38451831
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Twelve-month progression-free survival with sotorasib and panitumumab in KRAS G12C mutant metastatic colorectal cancer.
    Kavgaci G; Dizdar O; Yalcin S
    Anticancer Drugs; 2024 Jun; 35(5):459-461. PubMed ID: 38451823
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Design, synthesis, in silico molecular docking, and ADMET studies of quinoxaline-isoxazole-piperazine conjugates as egfr-targeting agents.
    Ali MI; Thirukovela NS; Kumar GB; Dasari G; Badithapuram V; Manchal R; Bandari S
    Chem Biol Drug Des; 2024 Mar; 103(3):e14499. PubMed ID: 38444047
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. BCL-X
    Jenkins LJ; Luk IY; Chionh F; Tan T; Needham K; Ayton J; Reehorst CM; Vukelic N; Sieber OM; Mouradov D; Gibbs P; Williams DS; Tebbutt NC; Desai J; Hollande F; Dhillon AS; Lee EF; Merino D; Fairlie WD; Mariadason JM
    Cell Death Dis; 2024 Mar; 15(3):183. PubMed ID: 38429301
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Current advances in targeted therapy for metastatic colorectal cancer - Clinical translation and future directions.
    Johnson D; Chee CE; Wong W; Lam RCT; Tan IBH; Ma BBY
    Cancer Treat Rev; 2024 Apr; 125():102700. PubMed ID: 38422896
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Tumor location matters, next generation sequencing mutation profiling of left-sided, rectal, and right-sided colorectal tumors in 552 patients.
    Ciepiela I; Szczepaniak M; Ciepiela P; Hińcza-Nowak K; Kopczyński J; Macek P; Kubicka K; Chrapek M; Tyka M; Góźdź S; Kowalik A
    Sci Rep; 2024 Feb; 14(1):4619. PubMed ID: 38409377
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Fluoropyrimidine type, patient age, tumour sidedness and mutation status as determinants of benefit in patients with metastatic colorectal cancer treated with egfr monoclonal antibodies: individual patient data pooled analysis of randomised trials from the ARCAD database.
    Karapetis CS; Liu H; Sorich MJ; Pederson LD; Van Cutsem E; Maughan T; Douillard JY; O'Callaghan CJ; Jonker D; Bokemeyer C; Sobrero A; Cremolini C; Chibaudel B; Zalcberg J; Adams R; Buyse M; Peeters M; Yoshino T; de Gramont A; Shi Q
    Br J Cancer; 2024 May; 130(8):1269-1278. PubMed ID: 38402342
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. A Challenging Correlation between Tumor Cellularity and Somatic Variant Allele Fraction in Lung and colorectal cancers-Specimens of Low Tumor Percentage Should Be Analyzed with Caution.
    Zarabi SK; Zhai L; Cheng YW
    Biomolecules; 2024 Jan; 14(2):. PubMed ID: 38397405
    [No Abstract]    [Full Text] [Related]  


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