BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND FGFR4, CD334, 2264, ENSG00000160867, P22455, MGC20292, TKF, JTK2
46 results:

  • 1. Predictive significance of fgfr4 p.G388R polymorphism in metastatic colorectal cancer patients receiving trifluridine/tipiracil (TAS-102) treatment.
    Ottaiano A; Santorsola M; Ianniello M; Ceccarelli A; Casillo M; Sabbatino F; Petrillo N; Cascella M; Caraglia F; Picone C; Perri F; Sirica R; Zappavigna S; Nasti G; Savarese G; Caraglia M
    J Transl Med; 2024 Apr; 22(1):379. PubMed ID: 38650006
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Insight into the design of fgfr4 selective inhibitors in cancer therapy: Prospects and challenges.
    Chen X; Huang Y; Chen B; Liu H; Cai Y; Yang Y
    Eur J Med Chem; 2024 Jan; 263():115947. PubMed ID: 37976704
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Design, synthesis, and biological evaluation of 1,6-naphthyridine-2-one derivatives as novel fgfr4 inhibitors for the treatment of colorectal cancer.
    Fang B; Lai Y; Yan H; Ma Y; Ni Z; Zhu Q; Zhang J; Ye Y; Wang M; Wang P; Wang Y; Zhang S; Hui M; Wang D; Zhao Y; Li X; Wang K; Liu Z
    Eur J Med Chem; 2023 Nov; 259():115703. PubMed ID: 37556948
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. FGF19-Induced Inflammatory CAF Promoted Neutrophil Extracellular Trap Formation in the Liver Metastasis of colorectal cancer.
    Li C; Chen T; Liu J; Wang Y; Zhang C; Guo L; Shi D; Zhang T; Wang X; Li J
    Adv Sci (Weinh); 2023 Aug; 10(24):e2302613. PubMed ID: 37345586
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating fgfr4 and SRC.
    Chen X; Chen J; Feng W; Huang W; Wang G; Sun M; Luo X; Wang Y; Nie Y; Fan D; Wu K; Xia L
    Theranostics; 2023; 13(4):1401-1418. PubMed ID: 36923538
    [No Abstract]    [Full Text] [Related]  

  • 6. Berbamine dihydrochloride suppresses the progression of colorectal cancer via RTKs/Akt axis.
    Liu L; Liang D; Zheng Q; Zhao M; Lv R; Tang J; Chen N
    J Ethnopharmacol; 2023 Mar; 303():116025. PubMed ID: 36496042
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. DCZ0415, a small-molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the fgfr4/STAT3 axis and the Wnt/β-catenin pathway in colorectal cancer.
    Agarwal S; Afaq F; Bajpai P; Kim HG; Elkholy A; Behring M; Chandrashekar DS; Diffalha SA; Khushman M; Sugandha SP; Varambally S; Manne U
    Mol Oncol; 2022 Apr; 16(8):1728-1745. PubMed ID: 35194944
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. BCL-XL inhibition induces an fgfr4-mediated rescue response in colorectal cancer.
    Ramesh P; Di Franco S; Atencia Taboada L; Zhang L; Nicotra A; Stassi G; Medema JP
    Cell Rep; 2022 Feb; 38(7):110374. PubMed ID: 35172148
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Microarray-based identification of differentially expressed genes associated with andrographolide derivatives-induced resistance in colon and prostate cancer cell lines.
    Quah SY; Wong CC; Wong HC; Ho KL; Abdul Manan N; Deb PK; Sagineedu SR; Stanslas J
    Toxicol Appl Pharmacol; 2021 Aug; 425():115605. PubMed ID: 34087331
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status.
    Agarwal S; Behring M; Kim HG; Chandrashekar DS; Chakravarthi BVSK; Gupta N; Bajpai P; Elkholy A; Al Diffalha S; Datta PK; Heslin MJ; Varambally S; Manne U
    Mol Oncol; 2020 Dec; 14(12):3007-3029. PubMed ID: 33037736
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. A novel prognostic risk score model based on immune-related genes in patients with stage IV colorectal cancer.
    Xu K; He J; Zhang J; Liu T; Yang F; Ren T
    Biosci Rep; 2020 Oct; 40(10):. PubMed ID: 33034614
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Fibroblast growth factor receptor 4 increases epidermal growth factor receptor (EGFR) signaling by inducing amphiregulin expression and attenuates response to EGFR inhibitors in colon cancer.
    Hong CS; Sun EG; Choi JN; Kim DH; Kim JH; Ryu KH; Shim HJ; Hwang JE; Bae WK; Kim HR; Kim KK; Jung C; Chung IJ; Cho SH
    Cancer Sci; 2020 Sep; 111(9):3268-3278. PubMed ID: 32533590
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Role of fibroblast growth factor 4 in the growth and metastasis of colorectal cancer.
    Ye Y; Jiang D; Li J; Han C; Wang X; Wang F; Li J
    Int J Oncol; 2020 Jun; 56(6):1565-1573. PubMed ID: 32236572
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. colorectal screening using the immunochemical faecal occult blood test kit among the Malaysian cohort participants.
    Abdullah N; Abd Jalal N; Ismail N; Kamaruddin MA; Abd Mutalib NS; Alias MR; Mazlan L; Sagap I; Jamal R
    Cancer Epidemiol; 2020 Apr; 65():101656. PubMed ID: 31923638
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Crumbs3 is a critical factor that regulates invasion and metastasis of colon adenocarcinoma via the specific interaction with FGFR1.
    Iioka H; Saito K; Sakaguchi M; Tachibana T; Homma K; Kondo E
    Int J Cancer; 2019 Nov; 145(10):2740-2753. PubMed ID: 30980524
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic colorectal cancer.
    Duplaquet L; Figeac M; Leprêtre F; Frandemiche C; Villenet C; Sebda S; Sarafan-Vasseur N; Bénozène M; Vinchent A; Goormachtigh G; Wicquart L; Rousseau N; Beaussire L; Truant S; Michel P; Sabourin JC; Galateau-Sallé F; Copin MC; Zalcman G; De Launoit Y; Fafeur V; Tulasne D
    Mol Cancer Ther; 2019 Jun; 18(6):1137-1148. PubMed ID: 30926633
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Proteomic profiling reveals key cancer progression modulators in shed microvesicles released from isogenic human primary and metastatic colorectal cancer cell lines.
    Suwakulsiri W; Rai A; Xu R; Chen M; Greening DW; Simpson RJ
    Biochim Biophys Acta Proteins Proteom; 2019 Dec; 1867(12):140171. PubMed ID: 30502510
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Upregulation of Fibroblast Growth Factor 19 Is Associated with the Initiation of colorectal Adenoma.
    Wang D; Zhang J; Li Z; Han J; Gao Y; Chen M; Li Y
    Dig Dis; 2019; 37(3):214-225. PubMed ID: 30517925
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Forkhead box C1 promotes colorectal cancer metastasis through transactivating ITGA7 and fgfr4 expression.
    Liu J; Zhang Z; Li X; Chen J; Wang G; Tian Z; Qian M; Chen Z; Guo H; Tang G; Huang W; Tian D; Wang D; Nie Y; Fan D; Wu K; Xia L
    Oncogene; 2018 Oct; 37(41):5477-5491. PubMed ID: 29884889
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Penetrance estimates for
    Evans DG; Woodward E; Harkness EF; Howell A; Plaskocinska I; Maher ER; Tischkowitz MD; Lalloo F
    J Med Genet; 2018 Jul; 55(7):442-448. PubMed ID: 29483236
    [TBL] [Abstract] [Full Text] [Related]  


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