Terms: = Colorectal cancer AND FGFR4, CD334, 2264, ENSG00000160867, P22455, MGC20292, TKF, JTK2 AND Treatment
19 results:
1. Predictive significance of fgfr4 p.G388R polymorphism in metastatic colorectal cancer patients receiving trifluridine/tipiracil (TAS-102) treatment.
Ottaiano A; Santorsola M; Ianniello M; Ceccarelli A; Casillo M; Sabbatino F; Petrillo N; Cascella M; Caraglia F; Picone C; Perri F; Sirica R; Zappavigna S; Nasti G; Savarese G; Caraglia M
J Transl Med; 2024 Apr; 22(1):379. PubMed ID: 38650006
[TBL] [Abstract] [Full Text] [Related]
2. Insight into the design of fgfr4 selective inhibitors in cancer therapy: Prospects and challenges.
Chen X; Huang Y; Chen B; Liu H; Cai Y; Yang Y
Eur J Med Chem; 2024 Jan; 263():115947. PubMed ID: 37976704
[TBL] [Abstract] [Full Text] [Related]
3. Design, synthesis, and biological evaluation of 1,6-naphthyridine-2-one derivatives as novel fgfr4 inhibitors for the treatment of colorectal cancer.
Fang B; Lai Y; Yan H; Ma Y; Ni Z; Zhu Q; Zhang J; Ye Y; Wang M; Wang P; Wang Y; Zhang S; Hui M; Wang D; Zhao Y; Li X; Wang K; Liu Z
Eur J Med Chem; 2023 Nov; 259():115703. PubMed ID: 37556948
[TBL] [Abstract] [Full Text] [Related]
4. DCZ0415, a small-molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the fgfr4/STAT3 axis and the Wnt/β-catenin pathway in colorectal cancer.
Agarwal S; Afaq F; Bajpai P; Kim HG; Elkholy A; Behring M; Chandrashekar DS; Diffalha SA; Khushman M; Sugandha SP; Varambally S; Manne U
Mol Oncol; 2022 Apr; 16(8):1728-1745. PubMed ID: 35194944
[TBL] [Abstract] [Full Text] [Related]
5. Microarray-based identification of differentially expressed genes associated with andrographolide derivatives-induced resistance in colon and prostate cancer cell lines.
Quah SY; Wong CC; Wong HC; Ho KL; Abdul Manan N; Deb PK; Sagineedu SR; Stanslas J
Toxicol Appl Pharmacol; 2021 Aug; 425():115605. PubMed ID: 34087331
[TBL] [Abstract] [Full Text] [Related]
6. A novel prognostic risk score model based on immune-related genes in patients with stage IV colorectal cancer.
Xu K; He J; Zhang J; Liu T; Yang F; Ren T
Biosci Rep; 2020 Oct; 40(10):. PubMed ID: 33034614
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7. Fibroblast growth factor receptor 4 increases epidermal growth factor receptor (EGFR) signaling by inducing amphiregulin expression and attenuates response to EGFR inhibitors in colon cancer.
Hong CS; Sun EG; Choi JN; Kim DH; Kim JH; Ryu KH; Shim HJ; Hwang JE; Bae WK; Kim HR; Kim KK; Jung C; Chung IJ; Cho SH
Cancer Sci; 2020 Sep; 111(9):3268-3278. PubMed ID: 32533590
[TBL] [Abstract] [Full Text] [Related]
8. Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic colorectal cancer.
Duplaquet L; Figeac M; Leprêtre F; Frandemiche C; Villenet C; Sebda S; Sarafan-Vasseur N; Bénozène M; Vinchent A; Goormachtigh G; Wicquart L; Rousseau N; Beaussire L; Truant S; Michel P; Sabourin JC; Galateau-Sallé F; Copin MC; Zalcman G; De Launoit Y; Fafeur V; Tulasne D
Mol Cancer Ther; 2019 Jun; 18(6):1137-1148. PubMed ID: 30926633
[TBL] [Abstract] [Full Text] [Related]
9. Forkhead box C1 promotes colorectal cancer metastasis through transactivating ITGA7 and fgfr4 expression.
Liu J; Zhang Z; Li X; Chen J; Wang G; Tian Z; Qian M; Chen Z; Guo H; Tang G; Huang W; Tian D; Wang D; Nie Y; Fan D; Wu K; Xia L
Oncogene; 2018 Oct; 37(41):5477-5491. PubMed ID: 29884889
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10. Combination of fgfr4 inhibitor Blu9931 and 5-fluorouracil effects on the biological characteristics of colorectal cancer cells.
Jiang D; Li J; Li J; Wang M; Han C; Wang X; Zhao C; Ye Y
Int J Oncol; 2017 Nov; 51(5):1611-1620. PubMed ID: 29048661
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11.
Cho SH; Hong CS; Kim HN; Shin MH; Kim KR; Shim HJ; Hwang JE; Bae WK; Chung IJ
Cancer Res Treat; 2017 Jul; 49(3):766-777. PubMed ID: 27857023
[TBL] [Abstract] [Full Text] [Related]
12. Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer.
Ahmed MA; Selzer E; Dörr W; Jomrich G; Harpain F; Silberhumer GR; Müllauer L; Holzmann K; Grasl-Kraupp B; Grusch M; Berger W; Marian B
Oncotarget; 2016 Oct; 7(43):69976-69990. PubMed ID: 27650548
[TBL] [Abstract] [Full Text] [Related]
13. FGF-1/-3/fgfr4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7.
Bai YP; Shang K; Chen H; Ding F; Wang Z; Liang C; Xu Y; Sun MH; Li YY
Cancer Sci; 2015 Oct; 106(10):1278-87. PubMed ID: 26183471
[TBL] [Abstract] [Full Text] [Related]
14. Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal cancer Patients Treated with 5-FU and Radiation.
Bohanes P; Rankin CJ; Blanke CD; Winder T; Ulrich CM; Smalley SR; Rich TA; Martensen JA; Benson AB; Mayer RJ; Cripps CM; Danenberg K; Makar KW; Zhang W; Benedetti JK; Lenz HJ
Clin Cancer Res; 2015 Apr; 21(7):1583-90. PubMed ID: 25589620
[TBL] [Abstract] [Full Text] [Related]
15. fgfr4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer.
Liu R; Li J; Xie K; Zhang T; Lei Y; Chen Y; Zhang L; Huang K; Wang K; Wu H; Wu M; Nice EC; Huang C; Wei Y
Cancer Res; 2013 Oct; 73(19):5926-35. PubMed ID: 23943801
[TBL] [Abstract] [Full Text] [Related]
16. Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling.
Pai R; Dunlap D; Qing J; Mohtashemi I; Hotzel K; French DM
Cancer Res; 2008 Jul; 68(13):5086-95. PubMed ID: 18593907
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17. Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.
Desnoyers LR; Pai R; Ferrando RE; Hötzel K; Le T; Ross J; Carano R; D'Souza A; Qing J; Mohtashemi I; Ashkenazi A; French DM
Oncogene; 2008 Jan; 27(1):85-97. PubMed ID: 17599042
[TBL] [Abstract] [Full Text] [Related]
18. Single nucleotide polymorphism in fibroblast growth factor receptor 4 at codon 388 is associated with prognosis in high-grade soft tissue sarcoma.
Morimoto Y; Ozaki T; Ouchida M; Umehara N; Ohata N; Yoshida A; Shimizu K; Inoue H
Cancer; 2003 Nov; 98(10):2245-50. PubMed ID: 14601095
[TBL] [Abstract] [Full Text] [Related]
19. Survival after repeat hepatic resection for recurrent colorectal metastases.
Chiappa A; Zbar AP; Biella F; Staudacher C
Hepatogastroenterology; 1999; 46(26):1065-70. PubMed ID: 10370668
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