Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND FH, HLRCC, 2271, ENSG00000091483, MCUL1, MCL, LRCC, P07954 AND Treatment
118 results:

  • 1. [Incidence of postoperative complications in Chinese patients with gastric or colorectal cancer based on a national, multicenter, prospective, cohort study].
    Zhang SQ; Wu ZQ; Huo BW; Xu HN; Zhao K; Jing CQ; Liu FL; Yu J; Li ZR; Zhang J; Zang L; Hao HK; Zheng CH; Li Y; Fan L; Huang H; Liang P; Wu B; Zhu JM; Niu ZJ; Zhu LH; Song W; You J; Yan S; Li ZY
    Zhonghua Wei Chang Wai Ke Za Zhi; 2024 Mar; 27(3):247-260. PubMed ID: 38532587
    [No Abstract]    [Full Text] [Related]  

  • 2. BCL-X
    Jenkins LJ; Luk IY; Chionh F; Tan T; Needham K; Ayton J; Reehorst CM; Vukelic N; Sieber OM; Mouradov D; Gibbs P; Williams DS; Tebbutt NC; Desai J; Hollande F; Dhillon AS; Lee EF; Merino D; Fairlie WD; Mariadason JM
    Cell Death Dis; 2024 Mar; 15(3):183. PubMed ID: 38429301
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The mechanism of anticancer effects of some pyrrolopyrimidine derivatives on HT-29 human colon cancer cells.
    Ergul M; Kilic-Kurt Z; Aka Y; Kutuk O; Sahin-Inan ZD
    Toxicol In Vitro; 2024 Mar; 95():105757. PubMed ID: 38061602
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Dual targeting of mcl-1 and Bcl-2 to overcome chemoresistance in cervical and colon cancer.
    Wang L; Xi C; Liu R; Ye T; Xiang N; Deng J; Li H
    Anticancer Drugs; 2024 Mar; 35(3):219-226. PubMed ID: 37948336
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. P53‑microRNA interactions regulate the response of colorectal tumor cells to oxaliplatin under normoxic and hypoxic conditions.
    Zhang J; Li C; Sun L; Sun D; Zhao T
    Oncol Rep; 2023 Dec; 50(6):. PubMed ID: 37921068
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Synthesis by diastereomeric resolution, biochemical evaluation and molecular modelling of chiral 3-hydroxyl b-lactam microtubule-targeting agents for the treatment of triple negative breast and chemoresistant colorectal cancers.
    McLoughlin EC; Twamley B; O'Brien JE; Hannon Barroeta P; Zisterer DM; Meegan MJ; O'Boyle NM
    Bioorg Chem; 2023 Dec; 141():106877. PubMed ID: 37804699
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Domino Liver Transplantation for Unresectable Colon cancer Liver Metastasis From a Donor With Heterozygous Familial Hyperlipidemia: A Case Report.
    Sambommatsu Y; Bruno DA; Imai D; Lee SD; Khan AA; Sharma A; Saeed M; Cotterell AH; Levy MF; Bhati C; Kumaran V
    Transplant Proc; 2023 Oct; 55(8):1930-1933. PubMed ID: 37661467
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Sphingosine kinase-2 silencing modulates sensitivity of HT-29 human colorectal cancer cells to paclitaxel-induced cell death through altering apoptosis-related proteins.
    Mu Y; Wang J; Li G
    Chem Biol Drug Des; 2023 Aug; 102(2):255-261. PubMed ID: 36929215
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. STAT3 regulates 5-Fu resistance in human colorectal cancer cells by promoting mcl-1-dependent cytoprotective autophagy.
    Yue Y; Zhang Q; Wang X; Sun Z
    Cancer Sci; 2023 Jun; 114(6):2293-2305. PubMed ID: 36788743
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins.
    Li J; Chen CH; O'Neill KL; Fousek-Schuller VJ; Black AR; Black JD; Zhang J; Luo X
    J Biol Chem; 2023 Feb; 299(2):102875. PubMed ID: 36621626
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Locoregionally Recurrent Colon cancer: How Far Have We Come? A Population-Based, Retrospective Cohort Study.
    Swartjes H; van Lankveld DWP; van Erning FN; Verheul HMW; de Wilt JHW; Koëter T; Vissers PAJ
    Ann Surg Oncol; 2023 Mar; 30(3):1726-1734. PubMed ID: 36261752
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. BCAP31 is involved in modulating colorectal cancer cell proliferation via the Emerin/β-catenin axis.
    Han L; Shi J; Zhao L; Deng J; Li Y; Zhao H; Wang H; Yan Y; Zou F
    Exp Cell Res; 2022 Sep; 418(1):113265. PubMed ID: 35716785
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Tannic acid attenuate AKT phosphorylation to inhibit UMUC3 bladder cancer cell proliferation.
    Chen MC; Annseles Rajula S; Bharath Kumar V; Hsu CH; Day CH; Chen RJ; Wang TF; Viswanadha VP; Li CC; Huang CY
    Mol Cell Biochem; 2022 Dec; 477(12):2863-2869. PubMed ID: 35691981
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. FL118, acting as a 'molecular glue degrader', binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c-Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy.
    Ling X; Wu W; Aljahdali IAM; Liao J; Santha S; Fountzilas C; Boland PM; Li F
    Clin Transl Med; 2022 May; 12(5):e881. PubMed ID: 35604033
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. mcl-1 levels critically impact the sensitivities of human colorectal cancer cells to APG-1252-M1, a novel Bcl-2/Bcl-X
    Yao W; Bai L; Wang S; Zhai Y; Sun SY
    Neoplasia; 2022 Jul; 29():100798. PubMed ID: 35462114
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The Interaction Between cancer-associated Fibroblasts and cancer Cells Enhances Bcl-xL and mcl-1 in colorectal cancer.
    Maeda A; Takahashi H; Harata S; Watanabe K; Yanagita T; Suzuki T; Ushigome H; Nakai N; Maeda Y; Hirokawa T; Shiga K; Ogawa R; Hara M; Matsuo Y; Mitsui A; Kimura M; Takiguchi S
    Anticancer Res; 2022 Mar; 42(3):1277-1288. PubMed ID: 35220217
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Bcl-2/Bcl-xL inhibitor ABT-263 overcomes hypoxia-driven radioresistence and improves radiotherapy.
    Ritter V; Krautter F; Klein D; Jendrossek V; Rudner J
    Cell Death Dis; 2021 Jul; 12(7):694. PubMed ID: 34257274
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Irreversible JNK blockade overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.
    Sun L; Patai ÁV; Hogenson TL; Fernandez-Zapico ME; Qin B; Sinicrope FA
    Oncogene; 2021 Aug; 40(32):5105-5115. PubMed ID: 34193942
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. BH3 Mimetic Sensitivity of colorectal cancer Cell Lines in Correlation with Molecular Features Identifies Predictors of Response.
    Zhang L; Ramesh P; Steinmetz M; Medema JP
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33917026
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis.
    Koumaki K; Kontogianni G; Kosmidou V; Pahitsa F; Kritsi E; Zervou M; Chatziioannou A; Souliotis VL; Papadodima O; Pintzas A
    Biochim Biophys Acta Mol Basis Dis; 2021 Apr; 1867(4):166061. PubMed ID: 33385518
    [TBL] [Abstract] [Full Text] [Related]  


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