Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND HSP90AA1, ENSG00000080824, 3320, P07900, LAP2, HSPN, HSPCAL4, HSPCAL1, HSPCA, HSPC1, HSP90N, HSP90A, Hsp90, Hsp89, HSP86, FLJ31884 AND Treatment
99 results:

  • 1. Discovery of a novel small-molecule activator of SIRT3 that inhibits cell proliferation and migration by apoptosis and autophagy-dependent cell death pathways in colorectal cancer.
    Mou Y; Chen Y; Fan Z; Ye L; Hu B; Han B; Wang G
    Bioorg Chem; 2024 May; 146():107327. PubMed ID: 38579616
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Prediction of potential mechanisms of rhubarb therapy for colorectal cancer based on network pharmacological analysis and molecular docking.
    Yang F; Li X; Zhang Y; Ren Y; Zhang J; Xiao K
    Medicine (Baltimore); 2024 Mar; 103(12):e37477. PubMed ID: 38518016
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Light-enhanced VEGF
    Longva AS; Berg K; Weyergang A
    Front Immunol; 2023; 14():1278000. PubMed ID: 38173721
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  • 4.
    Jung EJ; Kim HJ; Shin SC; Kim GS; Jung JM; Hong SC; Kim CW; Lee WS
    Int J Mol Sci; 2023 Dec; 24(24):. PubMed ID: 38139333
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  • 5. Inhibition of TRAP1 Accelerates the DNA Damage Response, Activation of the Heat Shock Response and Metabolic Reprogramming in Colon cancer Cells.
    Bhasin N; Dabral P; Senavirathna L; Pan S; Chen R
    Front Biosci (Landmark Ed); 2023 Sep; 28(9):227. PubMed ID: 37796715
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  • 6. Deactivation of glycogen synthase kinase-3β by heat shock‑inducible tumor small protein attenuates hyperthermia‑induced pro‑migratory activity in colorectal cancer cells.
    Koizumi K; Domoto T; Minamoto T; Satomura K; Nakajima H
    Int J Oncol; 2023 Aug; 63(2):. PubMed ID: 37387443
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  • 7. LncRNA NNT-AS1/hsa-miR-485-5p/hsp90 axis in-silico and clinical prospect correlated-to histologic grades-based CRC stratification: A step toward ncRNA Precision.
    El-Sheikh NM; Abulsoud AI; Fawzy A; Wasfey EF; Hamdy NM
    Pathol Res Pract; 2023 Jul; 247():154570. PubMed ID: 37244051
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  • 8. Heat shock protein 90 (hsp90) inhibitors in gastrointestinal cancer: where do we currently stand?-A systematic review.
    Magyar CTJ; Vashist YK; Stroka D; Kim-Fuchs C; Berger MD; Banz VM
    J Cancer Res Clin Oncol; 2023 Aug; 149(10):8039-8050. PubMed ID: 36966394
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  • 9. Native Size-Exclusion Chromatography-Based Mass Spectrometry Reveals New Components of the Early Heat Shock Protein 90 Inhibition Response Among Limited Global Changes.
    Samant RS; Batista S; Larance M; Ozer B; Milton CI; Bludau I; Wu E; Biggins L; Andrews S; Hervieu A; Johnston HE; Al-Lazikhani B; Lamond AI; Clarke PA; Workman P
    Mol Cell Proteomics; 2023 Feb; 22(2):100485. PubMed ID: 36549590
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  • 10. A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway.
    Lin F; Zhang G; Yang X; Wang M; Wang R; Wan M; Wang J; Wu B; Yan T; Jia Y
    J Ethnopharmacol; 2023 Mar; 303():115933. PubMed ID: 36403742
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  • 11. Excessive HSP70/TLR2 activation leads to remodeling of the tumor immune microenvironment to resist chemotherapy sensitivity of mFOLFOX in colorectal cancer.
    Feng H; Guo Z; Chen X; Liu K; Li H; Jia W; Wang C; Luo F; Ji X; Zhang T; Zhao R; Cheng X
    Clin Immunol; 2022 Dec; 245():109157. PubMed ID: 36244673
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  • 12. Metabolic targeting of NRF2 potentiates the efficacy of the TRAP1 inhibitor G-TPP through reduction of ROS detoxification in colorectal cancer.
    Tsai HY; Bronner MP; March JK; Valentine JF; Shroyer NF; Lai LA; Brentnall TA; Pan S; Chen R
    Cancer Lett; 2022 Nov; 549():215915. PubMed ID: 36113636
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  • 13. Network Pharmacology and Molecular Docking Validation to Reveal the Pharmacological Mechanisms of Kangai Injection against colorectal cancer.
    Zheng BB; Wang Q; Yue Y; Li J; Li XJ; Wang X
    Biomed Res Int; 2022; 2022():3008842. PubMed ID: 36046463
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. DAB2IP down-regulates hsp90aa1 to inhibit the malignant biological behaviors of colorectal cancer.
    Zhang M; Peng Y; Yang Z; Zhang H; Xu C; Liu L; Zhao Q; Wu J; Wang H; Liu J
    BMC Cancer; 2022 May; 22(1):561. PubMed ID: 35590292
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  • 15. hsp90 inhibition acts synergistically with heat to induce a pro-immunogenic form of cell death in colon cancer cells.
    Mouratidis PXE; Ter Haar G
    Int J Hyperthermia; 2021; 38(1):1443-1456. PubMed ID: 34612127
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. TAS-116 (Pimitespib), an Oral hsp90 Inhibitor, in Combination with Nivolumab in Patients with colorectal cancer and Other Solid Tumors: An Open-Label, Dose-Finding, and Expansion Phase Ib Trial (EPOC1704).
    Kawazoe A; Itahashi K; Yamamoto N; Kotani D; Kuboki Y; Taniguchi H; Harano K; Naito Y; Suzuki M; Fukutani M; Higuchi T; Ikeno T; Wakabayashi M; Sato A; Koyama S; Nishikawa H; Shitara K
    Clin Cancer Res; 2021 Dec; 27(24):6709-6715. PubMed ID: 34593531
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Predictive value of red blood cell distribution width level on histological response and prognosis in colorectal liver metastases.
    Chen Q; Chen J; Deng Y; Huang Z; Zhao H; Cai J
    Ann Palliat Med; 2021 Sep; 10(9):9383-9397. PubMed ID: 34498473
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  • 18. hsp90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.
    Song D; Guo M; Xu S; Song X; Bai B; Li Z; Chen J; An Y; Nie Y; Wu K; Wang S; Zhao Q
    J Exp Clin Cancer Res; 2021 May; 40(1):170. PubMed ID: 33990203
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Ring-opening of five-membered heterocycles conjugated 4-isopropylresorcinol scaffold-based benzamides as hsp90 inhibitors suppressing tumor growth in vitro and in vivo.
    Liu YM; Tu HJ; Wu CH; Lai MJ; Yu SC; Chao MW; Wu YW; Teng CM; Pan SL; Liou JP
    Eur J Med Chem; 2021 Jul; 219():113428. PubMed ID: 33934008
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Discovery of novel celastrol-triazole derivatives with hsp90-Cdc37 disruption to induce tumor cell apoptosis.
    Li N; Chen C; Zhu H; Shi Z; Sun J; Chen L
    Bioorg Chem; 2021 Jun; 111():104867. PubMed ID: 33845380
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