Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND IDH2, P48735, 3418, ENSG00000182054, IDHM, mNADP-IDH, IDH, IDP, ICD-M AND Treatment
23 results:

  • 1. Regorafenib and glioblastoma: a literature review of preclinical studies, molecular mechanisms and clinical effectiveness.
    Mongiardi MP; Pallini R; D'Alessandris QG; Levi A; Falchetti ML
    Expert Rev Mol Med; 2024 Apr; 26():e5. PubMed ID: 38563164
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. M
    Peng Y; Liu QZ; Xu D; Fu JY; Zhang LX; Qiu L; Lin JG
    Biochem Pharmacol; 2023 Nov; 217():115856. PubMed ID: 37838274
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Glioma arising in the setting of mismatch repair deficiency-rare or are we missing it?
    Goyal A; Rao S; Rishi KS; Ramaswamy V; Sadashiva N; Santosh V
    Childs Nerv Syst; 2024 Jan; 40(1):233-237. PubMed ID: 37733272
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Cost-effectiveness of preventive aspirin use and intensive downstaging polypectomy in patients with familial adenomatous polyposis: A microsimulation modeling study.
    Saito E; Mutoh M; Ishikawa H; Kamo K; Fukui K; Hori M; Ito Y; Chen Y; Sigel B; Sekiguchi M; Hemmi O; Katanoda K
    Cancer Med; 2023 Sep; 12(18):19137-19148. PubMed ID: 37649281
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Mismatch Repair Deficiency and Lynch Syndrome Among Adult Patients With Glioma.
    Benusiglio PR; Elder F; Touat M; Perrier A; Sanson M; Colas C; Guerrini-Rousseau L; Tran DT; Trabelsi N; Carpentier C; Marie Y; Adam C; Bernier M; Cazals-Hatem D; Mokhtari K; Tran S; Mathon B; Capelle L; Dhooge M; Idbaih A; Alentorn A; Houillier C; Dehais C; Hoang-Xuan K; Cuzzubbo S; Carpentier A; Duval A; Coulet F; Bielle F
    JCO Precis Oncol; 2023 May; 7():e2200525. PubMed ID: 37262394
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Mismatch repair-deficient glioma with spatially distinct idh-mutant and idh-wild type components arising in the setting of Lynch syndrome.
    Tan H; Nerison C; Stateler C; Bowden SG; Raslan AM; Ambady P; Barajas RF; Wood MD
    Cold Spring Harb Mol Case Stud; 2023 Apr; 9(2):. PubMed ID: 37076313
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. idh2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-κB signaling to promote colorectal cancer progression.
    He X; Wu N; Li R; Zhang H; Zhao Y; Nie Y; Wu J
    Cell Oncol (Dordr); 2023 Feb; 46(1):145-164. PubMed ID: 36401762
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis (J-FAPP Study III): a multicenter prospective interventional study.
    Ishikawa H; Yamada M; Sato Y; Tanaka S; Akiko C; Tajika M; Doyama H; Takayama T; Ohda Y; Horimatsu T; Sano Y; Tanakaya K; Ikematsu H; Saida Y; Ishida H; Takeuchi Y; Kashida H; Kiriyama S; Hori S; Lee K; Tashiro J; Kobayashi N; Nakajima T; Suzuki S; Mutoh M;
    Endoscopy; 2023 Apr; 55(4):344-352. PubMed ID: 36216266
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors.
    Kim H; Lim KY; Park JW; Kang J; Won JK; Lee K; Shim Y; Park CK; Kim SK; Choi SH; Kim TM; Yun H; Park SH
    Lab Invest; 2022 Feb; 102(2):160-171. PubMed ID: 34848827
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. cancer-associated idh mutations induce Glut1 expression and glucose metabolic disorders through a PI3K/Akt/mTORC1-Hif1α axis.
    Liu X; Yamaguchi K; Takane K; Zhu C; Hirata M; Hikiba Y; Maeda S; Furukawa Y; Ikenoue T
    PLoS One; 2021; 16(9):e0257090. PubMed ID: 34516556
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Wild-type idh2 protects nuclear DNA from oxidative damage and is a potential therapeutic target in colorectal cancer.
    Qiao S; Lu W; Glorieux C; Li J; Zeng P; Meng N; Zhang H; Wen S; Huang P
    Oncogene; 2021 Sep; 40(39):5880-5892. PubMed ID: 34349242
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Challenges and Solutions in Choosing the Surgical treatment in Patients with Complicated Colon cancer Operated in an Emergency - A Retrospective Study.
    Mihailov R; Firescu D; Voicu D; Constantin GB; Beznea A; Rebegea L; Șerban C; Panaitescu E; Bîrlă R; Patraşcu T
    Chirurgia (Bucur); 2021; 116(3):312-330. PubMed ID: 34191712
    [No Abstract]    [Full Text] [Related]  

  • 13. Suppression of oxidative phosphorylation and idh2 sensitizes colorectal cancer to a naphthalimide derivative and mitoxantrone.
    Ge C; Wang Y; Feng Y; Wang S; Zhang K; Xu X; Zhang Z; Zhao Y; Wang Y; Gao L; Dai F; Xie S; Wang C
    Cancer Lett; 2021 Oct; 519():30-45. PubMed ID: 34166768
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Differential expression of the BCAT isoforms between breast cancer subtypes.
    Shafei MA; Flemban A; Daly C; Kendrick P; White P; Dean S; Qualtrough D; Conway ME
    Breast Cancer; 2021 May; 28(3):592-607. PubMed ID: 33367952
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Vitamin C in combination with inhibition of mutant idh1 synergistically activates TET enzymes and epigenetically modulates gene silencing in colon cancer cells.
    Gerecke C; Schumacher F; Berndzen A; Homann T; Kleuser B
    Epigenetics; 2020 Mar; 15(3):307-322. PubMed ID: 31505989
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Biologics, Immunotherapy, and Future Directions in the treatment of Advanced Cholangiocarcinoma.
    Saeed A; Park R; Al-Jumayli M; Al-Rajabi R; Sun W
    Clin Colorectal Cancer; 2019 Jun; 18(2):81-90. PubMed ID: 30905548
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Supra-physiological concentration of glyoxylate inhibits proliferation of human colon cancer cells through oxidative stress.
    Patra T; Ghosh P; Alam N; Murmu N
    Life Sci; 2018 Aug; 207():80-89. PubMed ID: 29852189
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. M
    Peng Y; Qiu L; Xu D; Zhang L; Yu H; Ding Y; Deng L; Lin J
    Life Sci; 2017 Sep; 185():63-72. PubMed ID: 28751160
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Pan-mutant idh1 inhibitor BAY 1436032 for effective treatment of idh1 mutant astrocytoma in vivo.
    Pusch S; Krausert S; Fischer V; Balss J; Ott M; Schrimpf D; Capper D; Sahm F; Eisel J; Beck AC; Jugold M; Eichwald V; Kaulfuss S; Panknin O; Rehwinkel H; Zimmermann K; Hillig RC; Guenther J; Toschi L; Neuhaus R; Haegebart A; Hess-Stumpp H; Bauser M; Wick W; Unterberg A; Herold-Mende C; Platten M; von Deimling A
    Acta Neuropathol; 2017 Apr; 133(4):629-644. PubMed ID: 28124097
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Metformin prevents DMH-induced colorectal cancer in diabetic rats by reversing the warburg effect.
    Jia Y; Ma Z; Liu X; Zhou W; He S; Xu X; Ren G; Xu G; Tian K
    Cancer Med; 2015 Nov; 4(11):1730-41. PubMed ID: 26376762
    [TBL] [Abstract] [Full Text] [Related]  


    of 2.