Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND JAK1, ENSG00000162434, P23458, JTK3, JAK1B, JAK1A, 3716
64 results:

  • 1. JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
    Pennel KAF; Hatthakarnkul P; Wood CS; Lian GY; Al-Badran SSF; Quinn JA; Legrini A; Inthagard J; Alexander PG; van Wyk H; Kurniawan A; Hashmi U; Gillespie MA; Mills M; Ammar A; Hay J; Andersen D; Nixon C; Rebus S; Chang DK; Kelly C; Harkin A; Graham J; Church D; Tomlinson I; Saunders M; Iveson T; Lannagan TRM; Jackstadt R; Maka N; Horgan PG; Roxburgh CSD; Sansom OJ; McMillan DC; Steele CW; Jamieson NB; Park JH; Roseweir AK; Edwards J
    J Exp Clin Cancer Res; 2024 Mar; 43(1):64. PubMed ID: 38424636
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. METTL3 promotes colorectal cancer progression through activating jak1/STAT3 signaling pathway.
    Sun Y; Gong W; Zhang S
    Cell Death Dis; 2023 Nov; 14(11):765. PubMed ID: 38001065
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Targeting VCP potentiates immune checkpoint therapy for colorectal cancer.
    Wang F; Qi Q; Qin B; Wang Y; Huang Y; Li Q; Shen X; Wang X; Yang S; Pan G; Chen J; Qin Z; Chen X; Yang Y; Zeng Y; Liu J; Li Y; Li Y; Cheng Z; Lin X; Xing F; Zhang Y; Wang G; Li K; Jiang Z; Zhang H
    Cell Rep; 2023 Nov; 42(11):113318. PubMed ID: 37865914
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Conditional Overall Survival After Diagnosis of Non-Metastatic Colon cancer: Impact of Laterality, MSI, and KRAS Status.
    Tran CG; Goffredo P; Mott SL; Suraju MO; Kohn JF; Mishra A; Vauthey JN; Hassan I
    Ann Surg Oncol; 2024 Jan; 31(1):142-151. PubMed ID: 37857983
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Microsatellite Instability and Mismatch Repair Deficiency Define a Distinct Subset of Lung cancers Characterized by Smoking Exposure, High Tumor Mutational Burden, and Recurrent Somatic MLH1 Inactivation.
    Yang SR; Gedvilaite E; Ptashkin R; Chang J; Ziegler J; Mata DA; Villafania LB; Nafa K; Hechtman JF; Benayed R; Zehir A; Benhamida J; Arcila ME; Mandelker D; Rudin CM; Paik PK; Drilon A; Schoenfeld AJ; Ladanyi M
    J Thorac Oncol; 2024 Mar; 19(3):409-424. PubMed ID: 37838086
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in colorectal cancer Organoids.
    Pickles OJ; Wanigasooriya K; Ptasinska A; Patel AJ; Robbins HL; Bryer C; Whalley CM; Tee L; Lal N; Pinna CMA; Elzefzafy N; Taniere P; Beggs AD; Middleton GM
    Cancer Res Commun; 2023 Aug; 3(8):1501-1513. PubMed ID: 37565053
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. SKAP1 Is a Novel Biomarker and Therapeutic Target for Gastric cancer: Evidence from Expression, Functional, and Bioinformatic Analyses.
    Zhu L; Yu Q; Li Y; Zhang M; Peng Z; Wang S; Quan Z; Gao D
    Int J Mol Sci; 2023 Jul; 24(14):. PubMed ID: 37511629
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing jak1.
    Pan Y; Shu G; Fu L; Huang K; Zhou X; Gui C; Liu H; Jin X; Chen M; Li P; Cen J; Feng Z; Lu J; Chen Z; Li J; Xu Q; Wang Y; Liang H; Wang Z; Deng Q; Chen W; Luo J; Yang J; Zhang J; Wei J
    Adv Sci (Weinh); 2023 Apr; 10(11):e2206792. PubMed ID: 36775874
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Base editing screens map mutations affecting interferon-γ signaling in cancer.
    Coelho MA; Cooper S; Strauss ME; Karakoc E; Bhosle S; Gonçalves E; Picco G; Burgold T; Cattaneo CM; Veninga V; Consonni S; Dinçer C; Vieira SF; Gibson F; Barthorpe S; Hardy C; Rein J; Thomas M; Marioni J; Voest EE; Bassett A; Garnett MJ
    Cancer Cell; 2023 Feb; 41(2):288-303.e6. PubMed ID: 36669486
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Hyperforin Suppresses Oncogenic Kinases and Induces Apoptosis in colorectal cancer Cells.
    Hsu LC; Kuo CY; Hsu FT; Chang HF; Ou JJ
    In Vivo; 2023; 37(1):182-189. PubMed ID: 36593022
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Downregulation of SLC9A8 Promotes Epithelial-Mesenchymal Transition and Metastasis in colorectal cancer Cells via the IL6-jak1/STAT3 Signaling Pathway.
    Liu W; Geng C; Li X; Li Y; Song S; Wang C
    Dig Dis Sci; 2023 May; 68(5):1873-1884. PubMed ID: 36583805
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Ataxia telangiectasia mutated kinase inhibition promotes irradiation-induced PD-L1 expression in tumour-associated macrophages through IFN-I/JAK signalling pathway.
    Gao Y; Li Y; Lin Z; Zeng Y; Huang Z; Han L; Zhong Y; Gong Y; Wu Q; Xie C
    Immunology; 2023 Feb; 168(2):346-361. PubMed ID: 36326481
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Microsatellite Instability-High Endometrial cancers with MLH1 Promoter Hypermethylation Have Distinct Molecular and Clinical Profiles.
    Manning-Geist BL; Liu YL; Devereaux KA; Paula ADC; Zhou QC; Ma W; Selenica P; Ceyhan-Birsoy O; Moukarzel LA; Hoang T; Gordhandas S; Rubinstein MM; Friedman CF; Aghajanian C; Abu-Rustum NR; Stadler ZK; Reis-Filho JS; Iasonos A; Zamarin D; Ellenson LH; Lakhman Y; Mandelker DL; Weigelt B
    Clin Cancer Res; 2022 Oct; 28(19):4302-4311. PubMed ID: 35849120
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Laparoscopic liver resection for colorectal liver metastases: retrospective analysis of prognostic factors and oncological outcomes in a single-center cohort.
    Taillieu E; De Meyere C; Nuytens F; Vanneste G; Libbrecht L; Alaerts H; Parmentier I; Verslype C; D'Hondt M
    Langenbecks Arch Surg; 2022 Sep; 407(6):2399-2414. PubMed ID: 35499586
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. CJ14939, a Novel JAK Inhibitor, Increases Oxaliplatin-induced Cell Death Through JAK/STAT Pathway in colorectal cancer.
    Hong JK; Kim DY; Shin JS; Ryu YS; Moon JH; Koh DI; Lee S; Lee J; Lee WJ; Lee EY; Jung SA; Kim SC; Yu HN; Kim MJ; Hong SW; Park SS; Jung J; Kim SM; Kim EH; Jeong HR; Gong JH; Kim J; Kim TW; Jin DH
    Anticancer Res; 2022 Apr; 42(4):1813-1819. PubMed ID: 35346999
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. B2M and jak1/2-mutated MSI-H colorectal Carcinomas Can Benefit From Anti-PD-1 Therapy.
    Zhang C; Li D; Xiao B; Zhou C; Jiang W; Tang J; Li Y; Zhang R; Han K; Hou Z; Zhang L; Sui Q; Liao L; Pan Z; Zhang X; Ding P
    J Immunother; 2022 May; 45(4):187-193. PubMed ID: 35343934
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Lactylation-driven METTL3-mediated RNA m
    Xiong J; He J; Zhu J; Pan J; Liao W; Ye H; Wang H; Song Y; Du Y; Cui B; Xue M; Zheng W; Kong X; Jiang K; Ding K; Lai L; Wang Q
    Mol Cell; 2022 May; 82(9):1660-1677.e10. PubMed ID: 35320754
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Effects of Vitexin, a Natural Flavonoid Glycoside, on the Proliferation, Invasion, and Apoptosis of Human U251 Glioblastoma Cells.
    Huang J; Zhou Y; Zhong X; Su F; Xu L
    Oxid Med Cell Longev; 2022; 2022():3129155. PubMed ID: 35281458
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape.
    Glaire MA; Ryan NA; Ijsselsteijn ME; Kedzierska K; Obolenski S; Ali R; Crosbie EJ; Bosse T; de Miranda NF; Church DN
    J Pathol; 2022 Jul; 257(3):340-351. PubMed ID: 35262923
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Urinary detection of early responses to checkpoint blockade and of resistance to it via protease-cleaved antibody-conjugated sensors.
    Mac QD; Sivakumar A; Phuengkham H; Xu C; Bowen JR; Su FY; Stentz SZ; Sim H; Harris AM; Li TT; Qiu P; Kwong GA
    Nat Biomed Eng; 2022 Mar; 6(3):310-324. PubMed ID: 35241815
    [TBL] [Abstract] [Full Text] [Related]  


    of 4.