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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND JAK2, ENSG00000096968, O60674, JTK10, 3717
172 results:

  • 1. Exosomal miR-106a-5p from highly metastatic colorectal cancer cells drives liver metastasis by inducing macrophage M2 polarization in the tumor microenvironment.
    Liang Y; Li J; Yuan Y; Ju H; Liao H; Li M; Liu Y; Yao Y; Yang L; Li T; Lei X
    J Exp Clin Cancer Res; 2024 Oct; 43(1):281. PubMed ID: 39385295
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Demethylzeylasteral alleviates inflammation and colitis via dual suppression of NF-κB and STAT3/5 by targeting IKKα/β and jak2.
    Wen T; Liu T; Chen H; Liu Q; Shen X; Hu Q
    Int Immunopharmacol; 2024 Dec; 142(Pt B):113260. PubMed ID: 39340986
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Baicalein Enhances Radiosensitivity in colorectal cancer via jak2/STAT3 Pathway Inhibition.
    Yu Q; Tang R; Mo W; Zhao L; Li L
    Chem Biol Drug Des; 2024 Aug; 104(2):e14611. PubMed ID: 39152534
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Interleukin-6 serves as a critical factor in various cancer progression and therapy.
    Mohamed AH; Ahmed AT; Al Abdulmonem W; Bokov DO; Shafie A; Al-Hetty HRAK; Hsu CY; Alissa M; Nazir S; Jamali MC; Mudhafar M
    Med Oncol; 2024 Jun; 41(7):182. PubMed ID: 38900329
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. CLK3 positively promoted colorectal cancer proliferation by activating IL-6/STAT3 signaling.
    Ma Y; Gao F; Liu Y
    Exp Cell Res; 2024 Jul; 440(1):114132. PubMed ID: 38885806
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Exploring active ingredients and mechanisms of Coptidis Rhizoma-ginger against colon cancer using network pharmacology and molecular docking.
    Zeng T; Ling C; Liang Y
    Technol Health Care; 2024; 32(S1):523-542. PubMed ID: 38759074
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Vesicle-associated membrane protein 8 knockdown exerts anti-proliferative, pro-apoptotic, anti-autophagic, and pro-ferroptotic effects on colorectal cancer cells by inhibition of the JAK/STAT3 pathway.
    Xu Y; Yang T; Xu Q; Tang Y; Yang Q
    J Bioenerg Biomembr; 2024 Aug; 56(4):419-431. PubMed ID: 38720136
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. [Upregulating KLF11 ameliorates intestinal inflammation in mice with 2, 4, 6-trinitrobenesulfonic acid-induced colitis by inhibiting the jak2/STAT3 signaling pathway].
    Xi J; Zhang M; Zhang Y; Zhang C; Zhang Y; Wang R; Shen L; Li J; Song X
    Nan Fang Yi Ke Da Xue Xue Bao; 2024 Apr; 44(4):765-772. PubMed ID: 38708511
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Baicalein triggers ferroptosis in colorectal cancer cells via blocking the jak2/STAT3/GPX4 axis.
    Lai JQ; Zhao LL; Hong C; Zou QM; Su JX; Li SJ; Zhou XF; Li ZS; Deng B; Cao J; Qi Q
    Acta Pharmacol Sin; 2024 Aug; 45(8):1715-1726. PubMed ID: 38684798
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Upregulation of EMR1 (ADGRE1) by Tumor-Associated Macrophages Promotes Colon cancer Progression by Activating the jak2/STAT1,3 Signaling Pathway in Tumor Cells.
    Akter R; Park R; Lee SK; Han EJ; Park KS; Park J; Cho MY
    Int J Mol Sci; 2024 Apr; 25(8):. PubMed ID: 38673975
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Mitotic Spindle Positioning (MISP) Facilitates colorectal cancer Progression by Forming a Complex with Opa Interacting Protein 5 (OIP5) and Activating the jak2-STAT3 Signaling Pathway.
    Hiura K; Watanabe M; Hirose N; Nakano K; Okamura T; Sasaki H; Sasaki N
    Int J Mol Sci; 2024 Mar; 25(5):. PubMed ID: 38474305
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
    Pennel KAF; Hatthakarnkul P; Wood CS; Lian GY; Al-Badran SSF; Quinn JA; Legrini A; Inthagard J; Alexander PG; van Wyk H; Kurniawan A; Hashmi U; Gillespie MA; Mills M; Ammar A; Hay J; Andersen D; Nixon C; Rebus S; Chang DK; Kelly C; Harkin A; Graham J; Church D; Tomlinson I; Saunders M; Iveson T; Lannagan TRM; Jackstadt R; Maka N; Horgan PG; Roxburgh CSD; Sansom OJ; McMillan DC; Steele CW; Jamieson NB; Park JH; Roseweir AK; Edwards J
    J Exp Clin Cancer Res; 2024 Mar; 43(1):64. PubMed ID: 38424636
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Kurarinone targets jak2-STAT3 signaling in colon cancer-stem-like cells.
    Prajapati KS; Kumar S
    Cell Biochem Funct; 2024 Mar; 42(2):e3959. PubMed ID: 38390770
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Chemopreventive Effects of Polysaccharides and Flavonoids from Okra Flowers in Azomethane/Dextran Sulfate Sodium-Induced Murine Colitis-Associated cancer.
    Deng Y; Huang X; Chen X; Wang M; Tian L; Zhou H; Yang W; He F; Yin W
    Nutrients; 2023 Nov; 15(22):. PubMed ID: 38004214
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Crocin exerts anti-tumor effect in colon cancer cells via repressing the JAK pathway.
    Yang H; Zhang Y; Zhang D; Qian L; Yang T; Wu X
    Eur J Histochem; 2023 Sep; 67(3):. PubMed ID: 37700733
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Phosphorylation of PPDPF via IL6-jak2 activates the Wnt/β-catenin pathway in colorectal cancer.
    Zi Y; Liu L; Gao J; Xu X; Guan Y; Rong Z; Cao Z; Li M; Zeng Z; Fan Q; Tang F; He J; Feng D; Chen J; Dai Y; Huang Y; Nie Y; Pei H; Cai Q; Li Z; Sun L; Deng Y
    EMBO Rep; 2023 Sep; 24(9):e55060. PubMed ID: 37477088
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Artificial Downregulation of Ribosomal Protein L34 Restricts the Proliferation and Metastasis of colorectal cancer by Suppressing the
    Liang YC; Li R; Bao SR; Li ZL; Yin HZ; Dai CL
    Hum Gene Ther; 2023 Aug; 34(15-16):719-731. PubMed ID: 37427415
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. FGF19-Induced Inflammatory CAF Promoted Neutrophil Extracellular Trap Formation in the Liver Metastasis of colorectal cancer.
    Li C; Chen T; Liu J; Wang Y; Zhang C; Guo L; Shi D; Zhang T; Wang X; Li J
    Adv Sci (Weinh); 2023 Aug; 10(24):e2302613. PubMed ID: 37345586
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Furanocoumarin Notopterol: Inhibition of Hepatocellular Carcinogenesis through Suppression of cancer Stemness Signaling and Induction of Oxidative Stress-Associated Cell Death.
    Huang TY; Yang CK; Chen MY; Yadav VK; Fong IH; Yeh CT; Cherng YG
    Nutrients; 2023 May; 15(11):. PubMed ID: 37299411
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Association between the methylation of CpG islands in JAK-STAT pathway-related genes and colorectal cancer.
    Rong J; Pu R; Sun H; Liu Y; Tian T; Bi H; Xia T; Zhang L; Zhang Y; Zhao Y; Zhu L
    Gene; 2023 Jun; 868():147357. PubMed ID: 36914143
    [TBL] [Abstract] [Full Text] [Related]  


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