Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND JAK2, ENSG00000096968, O60674, JTK10, 3717 AND Prognosis
27 results:

  • 1. JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
    Pennel KAF; Hatthakarnkul P; Wood CS; Lian GY; Al-Badran SSF; Quinn JA; Legrini A; Inthagard J; Alexander PG; van Wyk H; Kurniawan A; Hashmi U; Gillespie MA; Mills M; Ammar A; Hay J; Andersen D; Nixon C; Rebus S; Chang DK; Kelly C; Harkin A; Graham J; Church D; Tomlinson I; Saunders M; Iveson T; Lannagan TRM; Jackstadt R; Maka N; Horgan PG; Roxburgh CSD; Sansom OJ; McMillan DC; Steele CW; Jamieson NB; Park JH; Roseweir AK; Edwards J
    J Exp Clin Cancer Res; 2024 Mar; 43(1):64. PubMed ID: 38424636
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Crocin exerts anti-tumor effect in colon cancer cells via repressing the JAK pathway.
    Yang H; Zhang Y; Zhang D; Qian L; Yang T; Wu X
    Eur J Histochem; 2023 Sep; 67(3):. PubMed ID: 37700733
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Furanocoumarin Notopterol: Inhibition of Hepatocellular Carcinogenesis through Suppression of cancer Stemness Signaling and Induction of Oxidative Stress-Associated Cell Death.
    Huang TY; Yang CK; Chen MY; Yadav VK; Fong IH; Yeh CT; Cherng YG
    Nutrients; 2023 May; 15(11):. PubMed ID: 37299411
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Linalool Impress colorectal cancer Deterioration by Mediating AKT/mTOR and jak2/STAT3 Signaling Pathways.
    Hou M; Zhang Y; Huang Q; Zhan H; Jia T; Li M; Hu J; Zhao Y
    Biomed Res Int; 2022; 2022():4801703. PubMed ID: 35860797
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Downregulation of STK25 promotes autophagy via the Janus kinase 2/signal transducer and activator of transcription 3 pathway in colorectal cancer.
    Chen J; Gao P; Peng L; Liu T; Wu F; Xu K; Chen L; Tan F; Xing P; Wang Z; Di J; Jiang B; Su X
    Mol Carcinog; 2022 Jun; 61(6):572-586. PubMed ID: 35349179
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Effects of Vitexin, a Natural Flavonoid Glycoside, on the Proliferation, Invasion, and Apoptosis of Human U251 Glioblastoma Cells.
    Huang J; Zhou Y; Zhong X; Su F; Xu L
    Oxid Med Cell Longev; 2022; 2022():3129155. PubMed ID: 35281458
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Comprehensive review on naringenin and naringin polyphenols as a potent anticancer agent.
    Rauf A; Shariati MA; Imran M; Bashir K; Khan SA; Mitra S; Emran TB; Badalova K; Uddin MS; Mubarak MS; Aljohani ASM; Alhumaydhi FA; Derkho M; Korpayev S; Zengin G
    Environ Sci Pollut Res Int; 2022 May; 29(21):31025-31041. PubMed ID: 35119637
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation.
    Hu F; Song D; Yan Y; Huang C; Shen C; Lan J; Chen Y; Liu A; Wu Q; Sun L; Xu F; Hu F; Chen L; Luo X; Feng Y; Huang S; Hu J; Wang G
    Nat Commun; 2021 Jun; 12(1):3651. PubMed ID: 34131122
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Mucin 16 Promotes colorectal cancer Development and Progression Through Activation of Janus Kinase 2.
    Liu Z; Gu Y; Li X; Zhou L; Cheng X; Jiang H; Huang Y; Zhang Y; Xu T; Yang W; Huang Q
    Dig Dis Sci; 2022 Jun; 67(6):2195-2208. PubMed ID: 33982216
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Stress-induced phosphoprotein 1 facilitates breast cancer cell progression and indicates poor prognosis for breast cancer patients.
    Lin L; Wen J; Lin B; Xia E; Zheng C; Ye L; Wang Y; Wang O; Chen Y
    Hum Cell; 2021 May; 34(3):901-917. PubMed ID: 33665786
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Circular RNA circ_0000372 contributes to the proliferation, migration and invasion of colorectal cancer by elevating IL6 expression via sponging miR-495.
    Liu X; Qin Y; Tang X; Wang Y; Bian C; Zhong J
    Anticancer Drugs; 2021 Mar; 32(3):296-305. PubMed ID: 33534412
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. lncRNA ZNF667-AS1 (NR_036521.1) inhibits the progression of colorectal cancer via regulating ANK2/jak2 expression.
    Zhuang L; Ding W; Ding W; Zhang Q; Xu X; Xi D
    J Cell Physiol; 2021 Mar; 236(3):2178-2193. PubMed ID: 32853419
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The autophagy-independent role of BECN1 in colorectal cancer metastasis through regulating STAT3 signaling pathway activation.
    Hu F; Li G; Huang C; Hou Z; Yang X; Luo X; Feng Y; Wang G; Hu J; Cao Z
    Cell Death Dis; 2020 May; 11(5):304. PubMed ID: 32358527
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. ML264 inhibits osteosarcoma growth and metastasis via inhibition of jak2/STAT3 and WNT/β-catenin signalling pathways.
    Huang H; Han Y; Chen Z; Pan X; Yuan P; Zhao X; Zhu H; Wang J; Sun X; Shi P
    J Cell Mol Med; 2020 May; 24(10):5652-5664. PubMed ID: 32285603
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Increased Risk of Acute Myelogenous Leukemia After Early Onset but Not Late-Onset colorectal cancer.
    Lehrer S; Rheinstein PH
    Am J Clin Oncol; 2020 Apr; 43(4):263-269. PubMed ID: 31876540
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The HOTAIR/miR-214/ST6GAL1 crosstalk modulates colorectal cancer procession through mediating sialylated c-Met via jak2/STAT3 cascade.
    Liu B; Liu Q; Pan S; Huang Y; Qi Y; Li S; Xiao Y; Jia L
    J Exp Clin Cancer Res; 2019 Nov; 38(1):455. PubMed ID: 31694696
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Analysis of clinical significance and prospective molecular mechanism of main elements of the JAK/STAT pathway in hepatocellular carcinoma.
    Wang X; Liao X; Yu T; Gong Y; Zhang L; Huang J; Yang C; Han C; Yu L; Zhu G; Qin W; Liu Z; Zhou X; Liu J; Han Q; Peng T
    Int J Oncol; 2019 Oct; 55(4):805-822. PubMed ID: 31485610
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis.
    Wei C; Yang C; Wang S; Shi D; Zhang C; Lin X; Liu Q; Dou R; Xiong B
    Mol Cancer; 2019 Mar; 18(1):64. PubMed ID: 30927925
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Autocrine activation of jak2 by IL-11 promotes platinum drug resistance.
    Zhou W; Sun W; Yung MMH; Dai S; Cai Y; Chen CW; Meng Y; Lee JB; Braisted JC; Xu Y; Southall NT; Shinn P; Huang X; Song Z; Chen X; Kai Y; Cai X; Li Z; Hao Q; Cheung ANY; Ngan HYS; Liu SS; Barak S; Hao J; Dai Z; Tzatsos A; Peng W; Pei H; Han Z; Chan DW; Zheng W; Zhu W
    Oncogene; 2018 Jul; 37(29):3981-3997. PubMed ID: 29662190
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. α7 nicotinic acetylcholine receptor in tumor-associated macrophages inhibits colorectal cancer metastasis through the jak2/STAT3 signaling pathway.
    Fei R; Zhang Y; Wang S; Xiang T; Chen W
    Oncol Rep; 2017 Nov; 38(5):2619-2628. PubMed ID: 28901507
    [TBL] [Abstract] [Full Text] [Related]  


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