Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND JUN, P05412, 3725, ENSG00000177606, AP1, c-Jun AND Treatment
260 results:

  • 1. Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling.
    Chomiak AA; Tiedemann RL; Liu Y; Kong X; Cui Y; Wiseman AK; Thurlow KE; Cornett EM; Topper MJ; Baylin SB; Rothbart SB
    Sci Adv; 2024 Mar; 10(13):eadk4423. PubMed ID: 38536911
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Prediction of potential mechanisms of rhubarb therapy for colorectal cancer based on network pharmacological analysis and molecular docking.
    Yang F; Li X; Zhang Y; Ren Y; Zhang J; Xiao K
    Medicine (Baltimore); 2024 Mar; 103(12):e37477. PubMed ID: 38518016
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Caffeic acid phenethyl ester mediates apoptosis in serum-starved HT29 colon cancer cells through modulation of heat shock proteins and MAPK pathways.
    Yahya S; Sulaiman MK; Sudhandiran G
    Cell Biochem Funct; 2024 Mar; 42(2):e3942. PubMed ID: 38379263
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in
    Jansen RA; Mainardi S; Dias MH; Bosma A; van Dijk E; Selig R; Albrecht W; Laufer SA; Zender L; Bernards R
    Proc Natl Acad Sci U S A; 2024 Feb; 121(9):e2319492121. PubMed ID: 38377196
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
    Zhao L; Miao H; Quan M; Wang S; Zhang Y; Zhou H; Zhang X; Lin Z; Piao J
    Chem Biol Interact; 2024 Feb; 389():110866. PubMed ID: 38218311
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Regorafenib monotherapy or combined with an immune-checkpoint inhibitor as later-line treatment for metastatic colorectal cancer: a multicenter, real-world retrospective study in China.
    Qu W; Liu Z; Chen X; Liu B; Zhao Y; Yan H; Qu X; Li S; Zang A; Sun Y; Zhu L; Zhou A
    BMC Cancer; 2024 Jan; 24(1):22. PubMed ID: 38166647
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis.
    Fan W; Cao D; Yang B; Wang J; Li X; Kitka D; Li TWH; You S; Shiao S; Gangi A; Posadas E; Di Vizio D; Tomasi ML; Seki E; Mato JM; Yang H; Lu SC
    J Hepatol; 2024 Mar; 80(3):443-453. PubMed ID: 38086446
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Cooperation of MLL1 and jun in controlling H3K4me3 on enhancers in colorectal cancer.
    Lin X; Chen JD; Wang CY; Cai Z; Zhan R; Yang C; Zhang LY; Li LY; Xiao Y; Chen MK; Wu M
    Genome Biol; 2023 Nov; 24(1):268. PubMed ID: 38012744
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Critical role of heme oxygenase-1 in chaetoglobosin A by triggering reactive oxygen species mediated mitochondrial apoptosis in colorectal cancer.
    Sun WC; Lin CL; Lee TH; Chang CH; Ong AZ; Yeh YH; Yu CL; Chen GW; Hsieh YH; Wang SW
    Free Radic Biol Med; 2023 Nov; 208():833-845. PubMed ID: 37776916
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Regorafenib activates oxidative stress by inhibiting SELENOS and potentiates oxaliplatin-induced cell death in colon cancer cells.
    Yu Y; Wu T; Zhang X; Li P; Ye L; Kuang J; Tao L; Ni L; Zhao Q; Zhang J; Pan H; Xie C; Zheng C; Li S; Cui R
    Eur J Pharmacol; 2023 Oct; 957():175986. PubMed ID: 37598924
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Real-world treatment patterns and clinical outcomes for chemotherapy-based regimens in first-line MSI-H/dMMR metastatic colorectal cancer.
    Amonkar MM; Chase M; Myer NM; Wang T; Turzhitsky V; Spira A
    Cancer Treat Res Commun; 2023; 36():100712. PubMed ID: 37301728
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Phosphorylation of Bcl-2 by JNK confers gemcitabine resistance in lung cancer cells by reducing autophagy-mediated cell death.
    Chiu CH; Ramesh S; Liao PH; Kuo WW; Chen MC; Kuo CH; Li CC; Wang TF; Lin YM; Lin YJ; Huang CY
    Environ Toxicol; 2023 Sep; 38(9):2121-2131. PubMed ID: 37219008
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis.
    Yang S; Hao S; Ye H; Zhang X
    Front Cell Infect Microbiol; 2023; 13():1083987. PubMed ID: 37009513
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Danggui Buxue Tang potentiates the cytotoxicity of 5-fluorouracil on colorectal adenocarcinoma cells: A signaling mediated by c-jun N-terminal kinase.
    Gong G; Zheng Y; Ganesan K; Xiong Q; Tsim KWK
    Phytother Res; 2023 Jul; 37(7):2864-2876. PubMed ID: 36810895
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  • 15. Genomic and epigenomic responses to aspirin in human colonic organoids.
    Witonsky D; Bielski MC; Li J; Lawrence KM; Mendoza IN; Usman H; Kupfer SS
    Physiol Genomics; 2023 Mar; 55(3):101-112. PubMed ID: 36645669
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. c-jun phosphorylated by JNK is required for protecting Gli2 from proteasomal-ubiquitin degradation by PGE2-JNK signaling axis.
    Yang J; Wang J; Zhang Y; Huang W; Zhang S; Yin P; Tan W
    Biochim Biophys Acta Mol Cell Res; 2023 Mar; 1870(3):119418. PubMed ID: 36581088
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Antiproliferative Evaluation of Novel 4-Imidazolidinone Derivatives as Anticancer Agent Which Triggers ROS-Dependent Apoptosis in colorectal cancer Cell.
    Huang J; Wang J; Song G; Hu C; Xu Z; Chen Z; Xu C; Yang D
    Molecules; 2022 Dec; 27(24):. PubMed ID: 36557977
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway.
    Lin F; Zhang G; Yang X; Wang M; Wang R; Wan M; Wang J; Wu B; Yan T; Jia Y
    J Ethnopharmacol; 2023 Mar; 303():115933. PubMed ID: 36403742
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. GPER Agonist G1 Prevents Wnt-Induced
    Abancens M; Harvey BJ; McBryan J
    Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36293473
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Downregulation of TEX11 promotes S-Phase progression and proliferation in colorectal cancer cells through the FOXO3a/COP1/c-jun/p21 axis.
    Zhang X; Hu F; Zhu B; Jiao X; Li Y; Wu S; Ren G; Li J; Xie Q; Pan Y; Li H; Zhao L
    Oncogene; 2022 Nov; 41(47):5133-5145. PubMed ID: 36258021
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