Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND KDR, VEGFR2, 3791, ENSG00000128052, P35968, VEGFR, CD309, FLK1
584 results:

  • 1. Allosteric SHP2 inhibition enhances regorafenib's effectiveness in colorectal cancer treatment.
    Han X; Wang W; Wang R; Zhang W; Zhu L; Xu Q; Guo W; Gu Y
    Biochem Biophys Res Commun; 2024 May; 709():149812. PubMed ID: 38564942
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  • 2. Regorafenib and glioblastoma: a literature review of preclinical studies, molecular mechanisms and clinical effectiveness.
    Mongiardi MP; Pallini R; D'Alessandris QG; Levi A; Falchetti ML
    Expert Rev Mol Med; 2024 Apr; 26():e5. PubMed ID: 38563164
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  • 3. Magnetic resonance imaging-based approaches for detecting the efficacy of combining therapy following vegfr-2 and PD-1 blockade in a colon cancer model.
    Xu X; Ma M; Ye K; Zhang D; Chen X; Wu J; Mo X; Xiao Z; Shi C; Luo L
    J Transl Med; 2024 Feb; 22(1):198. PubMed ID: 38395884
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  • 4. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating vegfr2 signal pathway in colorectal cancer.
    Wang S; Yang J; Kuang X; Li H; Du H; Wu Y; Xu F; Liu B
    J Ethnopharmacol; 2024 May; 326():117913. PubMed ID: 38360380
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Predictive value of CDC37 gene expression for targeted therapy in metastatic colorectal cancer.
    Arai H; Yang Y; Baca Y; Millstein J; Denda T; Ou FS; Innocenti F; Takeda H; Kubota Y; Doi A; Horie Y; Umemoto K; Izawa N; Wang J; Battaglin F; Jayachandran P; Algaze S; Soni S; Zhang W; Goldberg RM; Hall MJ; Scott AJ; Hwang JJ; Lou E; Weinberg BA; Marshall J; Goel S; Xiu J; Michael Korn W; Venook AP; Sunakawa Y; Lenz HJ
    Eur J Cancer; 2024 Apr; 201():113914. PubMed ID: 38359495
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  • 6. Effects of total coumarins from
    Liu Y; Cheng DH; Su ZY; Lv JH; Wang L; Deng YY; Li L
    Pharm Biol; 2024 Dec; 62(1):153-161. PubMed ID: 38347502
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  • 7. Design, synthesis, and anticancer evaluation of N-sulfonylpiperidines as potential vegfr-2 inhibitors, apoptotic inducers.
    Elgammal WE; Halawa AH; Eissa IH; Elkady H; Metwaly AM; Hassan SM; El-Agrody AM
    Bioorg Chem; 2024 Apr; 145():107157. PubMed ID: 38340473
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  • 8. Challenging the anticolorectal cancer capacity of quinoxaline-based scaffold via triazole ligation unveiled new efficient dual vegfr-2/MAO-B inhibitors.
    Ayoup MS; Ammar A; Abdel-Hamid H; Amer A; Abu-Serie MM; Nasr SA; Ghareeb DA; Teleb M; Tageldin GN
    Bioorg Chem; 2024 Feb; 143():107102. PubMed ID: 38211551
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  • 9. Glucagon Enhances Chemotherapy Efficacy By Inhibition of Tumor Vessels in colorectal cancer.
    Xu Y; Ni F; Sun D; Peng Y; Zhao Y; Wu X; Li S; Qi X; He X; Li M; Zhou Y; Zhang C; Yan M; Yao C; Zhu S; Yang Y; An B; Yang C; Zhang G; Jiang W; Mi J; Chen X; Wei P; Tian G; Zhang Y
    Adv Sci (Weinh); 2024 Feb; 11(6):e2307271. PubMed ID: 38072640
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  • 10. Zinc supplementation decreased incidence of grade ≥2 hand-foot skin reaction induced by regorafenib: A phase II randomized clinical trial.
    Huang WK; Hsu HC; Yang TS; Lu CW; Pan YR; Wu CE; Chung WH; Hung SI; Yeh CN
    Eur J Cancer; 2023 Dec; 195():113286. PubMed ID: 37968194
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  • 11. Low EGFL7 expression is associated with high lymph node spread and invasion of lymphatic vessels in colorectal cancer.
    de Oliveira C; Martins SFF; Gonçalves PG; Limone GA; Longatto-Filho A; Reis RM; Bidinotto LT
    Sci Rep; 2023 Nov; 13(1):19783. PubMed ID: 37957249
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  • 12. Comprehensive exploration of Biochanin A as an oncotherapeutics potential in the treatment of multivarious cancers with molecular insights.
    Sohel M
    Phytother Res; 2024 Feb; 38(2):489-506. PubMed ID: 37905329
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  • 13. Novel 3-phenylquinazolin-2,4(1H,3H)-diones as dual vegfr-2/c-Met-TK inhibitors: design, synthesis, and biological evaluation.
    Hassan A; Mosallam AM; Ibrahim AOA; Badr M; Abdelmonsef AH
    Sci Rep; 2023 Oct; 13(1):18567. PubMed ID: 37903949
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Antitumor activity of the new tyrphostin briva against BRAF
    Saleh K; Al Sakhen M; Kanaan S; Yasin S; Höpfner M; Tahtamouni L; Biersack B
    Invest New Drugs; 2023 Dec; 41(6):791-801. PubMed ID: 37870738
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. PD-1 and PD-L1 inhibitors in cold colorectal cancer: challenges and strategies.
    Lin KX; Istl AC; Quan D; Skaro A; Tang E; Zheng X
    Cancer Immunol Immunother; 2023 Dec; 72(12):3875-3893. PubMed ID: 37831146
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Vascular Endothelial Growth Factor-D (VEGF-D): An Angiogenesis Bypass in Malignant Tumors.
    Bokhari SMZ; Hamar P
    Int J Mol Sci; 2023 Aug; 24(17):. PubMed ID: 37686121
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  • 17. A new class of anticancer activity with computational studies for a novel bioactive aminophosphonates based on pyrazole moiety.
    Baren MH; Ibrahim SA; Al-Rooqi MM; Ahmed SA; El-Gamil MM; Hekal HA
    Sci Rep; 2023 Sep; 13(1):14680. PubMed ID: 37673913
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Integration of Hybridization Strategies in Pyridine-Urea Scaffolds for Novel Anticancer Agents: Design, Synthesis, and Mechanistic Insights.
    Godesi S; Nada H; Lee J; Kang JH; Kim SY; Choi Y; Lee K
    Molecules; 2023 Jun; 28(13):. PubMed ID: 37446614
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of colorectal cancer.
    Huntington KE; Louie AD; Srinivasan PR; Schorl C; Lu S; Silverberg D; Newhouse D; Wu Z; Zhou L; Borden BA; Giles FJ; Dooner M; Carneiro BA; El-Deiry WS
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37446056
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. colorectal cancer-secreted exosomal circ_001422 plays a role in regulating kdr expression and activating mTOR signaling in endothelial cells by targeting miR-195-5p.
    Ghafouri I; Pakravan K; Razmara E; Montazeri M; Rouhollah F; Babashah S
    J Cancer Res Clin Oncol; 2023 Oct; 149(13):12227-12240. PubMed ID: 37432457
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