Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132
67 results:

  • 1. Transcription Silencing and CpGs Hypermethylation as Therapeutic Gene Editing in Clinical colorectal Adenocarcinoma Repression.
    Al-Jumaili MMO
    Korean J Gastroenterol; 2024 Jan; 83(1):6-16. PubMed ID: 38268163
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Microsatellite Instability and Mismatch Repair Deficiency Define a Distinct Subset of Lung cancers Characterized by Smoking Exposure, High Tumor Mutational Burden, and Recurrent Somatic MLH1 Inactivation.
    Yang SR; Gedvilaite E; Ptashkin R; Chang J; Ziegler J; Mata DA; Villafania LB; Nafa K; Hechtman JF; Benayed R; Zehir A; Benhamida J; Arcila ME; Mandelker D; Rudin CM; Paik PK; Drilon A; Schoenfeld AJ; Ladanyi M
    J Thorac Oncol; 2024 Mar; 19(3):409-424. PubMed ID: 37838086
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Immunohistochemical expression of NRF2 is correlated with the magnitude of inflammation and fibrosis in chronic liver disease.
    To K; Okada K; Watahiki T; Suzuki H; Tsuchiya K; Tokushige K; Yamamoto M; Ariizumi SI; Shoda J
    Cancer Med; 2023 Oct; 12(19):19423-19437. PubMed ID: 37732511
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Investigation of Mutated in colorectal cancer (MCC) Gene Family Evolution History Indicates a Putative Role in Th17/Treg Differentiation.
    Kubick N; Paszkiewicz J; Bieńkowska I; Ławiński M; Horbańczuk JO; Sacharczuk M; Mickael ME
    Int J Mol Sci; 2023 Jul; 24(15):. PubMed ID: 37569317
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Nuclear Factor Erythroid 2-Related Factor 2/Kelch-Like ECH-Associated Protein 1 as a Predictor of Prognosis and Radiotherapy Resistance in Patients With Locally Advanced Rectal cancer: A Prospective Analysis.
    Park JM; Kim S; Bae SU; Byun SJ; Seo I; Lee HW
    J Korean Med Sci; 2023 Jul; 38(26):e200. PubMed ID: 37401495
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Effects of the juçara fruit (Euterpe edulis Martius) pulp and lyophilized extract on NRF2, keap1, SOD1, and GPX2 expression in human colorectal cancer cell lines.
    Milholli LA; Dalbó J; Couto CVMS; Oliveira MM; Santos JGD; Peterle GT; Archanjo AB; Silva PI; Boeloni JN; Nunes FD; Silva AMÁD; Trivilin LO
    Braz J Med Biol Res; 2023; 56():e12558. PubMed ID: 37075346
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis.
    Huang S; Li J; Wu S; Zheng Z; Wang C; Li H; Zhao L; Zhang X; Huang H; Huang C; Xie Q
    Oncogene; 2023 Apr; 42(17):1333-1346. PubMed ID: 36882524
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study.
    Wang J; Xiu J; Farrell A; Baca Y; Arai H; Battaglin F; Kawanishi N; Soni S; Zhang W; Millstein J; Shields AF; Grothey A; Weinberg BA; Marshall JL; Lou E; Khushman M; Sohal DPS; Hall MJ; Liu T; Oberley M; Spetzler D; Korn WM; Shen L; Lenz HJ
    Lancet Oncol; 2023 Feb; 24(2):151-161. PubMed ID: 36681091
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Blockage of Nrf2 and autophagy by L-selenocystine induces selective death in Nrf2-addicted colorectal cancer cells through p62-Keap-1-Nrf2 axis.
    Hsu WL; Wang CM; Yao CL; Chen SC; Nien CY; Sun YH; Tseng TY; Luo YH
    Cell Death Dis; 2022 Dec; 13(12):1060. PubMed ID: 36539411
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. ARD1 stabilizes NRF2 through direct interaction and promotes colon cancer progression.
    Fang X; Lee YH; Jang JH; Kim SJ; Kim SH; Kim DH; Na HK; Kim KO; Baek JH; Surh YJ
    Life Sci; 2023 Jan; 313():121217. PubMed ID: 36442525
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Small leucine zipper protein functions as a modulator for metabolic reprogramming of colorectal cancer cells by inducing nutrient stress-mediated autophagy.
    Kim S; Oh M; Kang M; Ko J
    Cell Mol Life Sci; 2022 Sep; 79(9):505. PubMed ID: 36057892
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Correlations of ALD, Keap-1, and FoxO4 expression with traditional tumor markers and clinicopathological characteristics in colorectal carcinoma.
    Huang P; Wang S; Wu Z; Zhou Z; Kuang M; Ren C; Qian X; Jiang A; Zhou Y; Wang X; Shao G
    Medicine (Baltimore); 2022 Aug; 101(34):e30222. PubMed ID: 36042628
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to keap1 to stabilize Nrf2.
    Han Y; Gao X; Wu N; Jin Y; Zhou H; Wang W; Liu H; Chu Y; Cao J; Jiang M; Yang S; Shi Y; Xie X; Chen F; Han Y; Qin W; Xu B; Liang J
    Cell Death Dis; 2022 Aug; 13(8):742. PubMed ID: 36038548
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. LTBP2 Knockdown Promotes Ferroptosis in Gastric cancer Cells through p62-keap1-Nrf2 Pathway.
    Wang T; Zhou Z; Wang C; Qin Y; Wu L; Hu B; Jin Q; Wei W; Huang M
    Biomed Res Int; 2022; 2022():6532253. PubMed ID: 35968244
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The tumour/normal tissue ratio of keap1 protein is a predictor for lymphovascular invasion in colorectal cancer: a correlation study between the Nrf2 and KRas pathways.
    Chang LC; Fan CW; Tseng WK; Chen JR; Hua CC
    Biomarkers; 2022 Nov; 27(7):701-707. PubMed ID: 35830714
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Gurgem-7 toxicity assessment: Regulation of cell survival or death by traditional Mongolian prescription.
    Batjargal A; Solek P; Kukula-Koch W; Urjin B; Koch W; Koman D; Dudzinska E
    Ecotoxicol Environ Saf; 2022 Jul; 239():113660. PubMed ID: 35605329
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Butyrate Drives Metabolic Rewiring and Epigenetic Reprogramming in Human Colon cancer Cells.
    Wang L; Shannar AAF; Wu R; Chou P; Sarwar MS; Kuo HC; Peter RM; Wang Y; Su X; Kong AN
    Mol Nutr Food Res; 2022 Jun; 66(12):e2200028. PubMed ID: 35429118
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Improvement of resistance to oxaliplatin by vorinostat in human colorectal cancer cells through inhibition of Nrf2 nuclear translocation.
    Tanaka S; Hosokawa M; Tatsumi A; Asaumi S; Imai R; Ogawara KI
    Biochem Biophys Res Commun; 2022 Jun; 607():9-14. PubMed ID: 35358872
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Landscape of
    Salem ME; El-Refai SM; Sha W; Puccini A; Grothey A; George TJ; Hwang JJ; O'Neil B; Barrett AS; Kadakia KC; Musselwhite LW; Raghavan D; Van Cutsem E; Tabernero J; Tie J
    JCO Precis Oncol; 2022 Mar; 6():e2100245. PubMed ID: 35319967
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma.
    Yuan L; Li S; Chen Q; Xia T; Luo D; Li L; Liu S; Guo S; Liu L; Du C; Jia G; Li X; Lu Z; Yang Z; Liu H; Mai H; Tang L
    Cell Death Differ; 2022 Aug; 29(8):1513-1527. PubMed ID: 35105963
    [TBL] [Abstract] [Full Text] [Related]  


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