Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND KMT2A, TRX1, 4297, MLL, ENSG00000118058, MLL/GAS7, HTRX1, HRX, ALL-1, MLL1A, CXXC7
79 results:

  • 1. Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in
    Jansen RA; Mainardi S; Dias MH; Bosma A; van Dijk E; Selig R; Albrecht W; Laufer SA; Zender L; Bernards R
    Proc Natl Acad Sci U S A; 2024 Feb; 121(9):e2319492121. PubMed ID: 38377196
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Nuclear translocation of thioredoxin-1 promotes colorectal cancer development via modulation of the IL-6/STAT3 signaling axis through interaction with STAT3.
    Wu A; Fang D; Liu Y; Shi X; Zhong Z; Zhou B; Ye L; Sun X; Jiang L
    Theranostics; 2023; 13(14):4730-4744. PubMed ID: 37771783
    [No Abstract]    [Full Text] [Related]  

  • 3. DPY30 Promotes Proliferation and Cell Cycle Progression of colorectal cancer Cells via Mediating H3K4 Trimethylation.
    Su WC; Mao XM; Li SY; Luo CY; Fan R; Jiang HF; Zhang LJ; Wang YT; Su GQ; Shen DY
    Int J Med Sci; 2023; 20(7):901-917. PubMed ID: 37324189
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Novel mutations in a second primary gastric cancer in a patient treated for primary colon cancer.
    Purwar R; Tripathi M; Rajput M; Pal M; Pandey M
    World J Surg Oncol; 2023 Jun; 21(1):173. PubMed ID: 37287033
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  • 5. CD169
    Saito Y; Fujiwara Y; Miyamoto Y; Ohnishi K; Nakashima Y; Tabata Y; Baba H; Komohara Y
    Cancer Med; 2023 May; 12(9):10199-10211. PubMed ID: 36846928
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Thioredoxin 1 supports colorectal cancer cell survival and promotes migration and invasion under glucose deprivation through interaction with G6PD.
    Lu F; Fang D; Li S; Zhong Z; Jiang X; Qi Q; Liu Y; Zhang W; Xu X; Liu Y; Zhu W; Jiang L
    Int J Biol Sci; 2022; 18(14):5539-5553. PubMed ID: 36147458
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  • 7. Correlation of KMT2 family mutations with molecular characteristics and prognosis in colorectal cancer.
    Liao C; Huang W; Lin M; Li H; Zhang Z; Zhang X; Chen R; Huang M; Yu P; Zhang S
    Int J Biol Markers; 2022 Jun; 37(2):149-157. PubMed ID: 35505597
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  • 8. The blood level of thioredoxin 1 as a supporting biomarker in the detection of breast cancer.
    Lee YJ; Kim Y; Choi BB; Kim JR; Ko HM; Suh KH; Lee JS
    BMC Cancer; 2022 Jan; 22(1):12. PubMed ID: 34979986
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  • 9. 'I Can't Keep Up!': an update on advances in soft tissue pathology occurring after the publication of the 2020 World Health Organization classification of soft tissue and bone tumours.
    Folpe AL
    Histopathology; 2022 Jan; 80(1):54-75. PubMed ID: 34958510
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  • 10. Laparoscopic versus open resection in patients with locally advanced colon cancer.
    Huynh C; Minkova S; Kim D; Stuart H; Hamilton TD
    Surgery; 2021 Dec; 170(6):1610-1615. PubMed ID: 34462119
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  • 11. PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment.
    Ji G; Zhou W; Du J; Zhou J; Wu D; Zhao M; Yang L; Hao A
    Cell Death Dis; 2021 Jun; 12(7):633. PubMed ID: 34148069
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Genome-scale CRISPR-Cas9 screen of Wnt/β-catenin signaling identifies therapeutic targets for colorectal cancer.
    Wan C; Mahara S; Sun C; Doan A; Chua HK; Xu D; Bian J; Li Y; Zhu D; Sooraj D; Cierpicki T; Grembecka J; Firestein R
    Sci Adv; 2021 May; 7(21):. PubMed ID: 34138730
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. High Yap and mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
    Heuberger J; Grinat J; Kosel F; Liu L; Kunz S; Vidal RO; Keil M; Haybaeck J; Robine S; Louvard D; Regenbrecht C; Sporbert A; Sauer S; von Eyss B; Sigal M; Birchmeier W
    Proc Natl Acad Sci U S A; 2021 Jun; 118(22):. PubMed ID: 34039707
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Advance care planning in patients with advanced cancer: A 6-country, cluster-randomised clinical trial.
    Korfage IJ; Carreras G; Arnfeldt Christensen CM; Billekens P; Bramley L; Briggs L; Bulli F; Caswell G; Červ B; van Delden JJM; Deliens L; Dunleavy L; Eecloo K; Gorini G; Groenvold M; Hammes B; Ingravallo F; Jabbarian LJ; Kars MC; Kodba-Čeh H; Lunder U; Miccinesi G; Mimić A; Ozbič P; Payne SA; Polinder S; Pollock K; Preston NJ; Seymour J; Simonič A; Thit Johnsen A; Toccafondi A; Verkissen MN; Wilcock A; Zwakman M; van der Heide A; Rietjens JAC
    PLoS Med; 2020 Nov; 17(11):e1003422. PubMed ID: 33186365
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. SOCS1 Represses Fractionated Ionizing Radiation-Induced EMT Signaling Pathways through the Counter-Regulation of ROS-Scavenging and ROS-Generating Systems.
    Kim S; Kim SH; Lee CE
    Cell Physiol Biochem; 2020 Oct; 54(5):1026-1040. PubMed ID: 33048478
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. cancer-derived UTX TPR mutations G137V and D336G impair interaction with mll3/4 complexes and affect UTX subcellular localization.
    Kato H; Asamitsu K; Sun W; Kitajima S; Yoshizawa-Sugata N; Okamoto T; Masai H; Poellinger L
    Oncogene; 2020 Apr; 39(16):3322-3335. PubMed ID: 32071397
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  • 17. ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin.
    Wen C; Wang H; Wu X; He L; Zhou Q; Wang F; Chen S; Huang L; Chen J; Wang H; Ye W; Li W; Yang X; Liu H; Peng J
    Cell Death Dis; 2019 Oct; 10(11):809. PubMed ID: 31649256
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. kmt2a histone methyltransferase contributes to colorectal cancer development by promoting cathepsin Z transcriptional activation.
    Fang Y; Zhang D; Hu T; Zhao H; Zhao X; Lou Z; He Y; Qin W; Xia J; Zhang X; Ye LC
    Cancer Med; 2019 Jul; 8(7):3544-3552. PubMed ID: 31090199
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Diagnostic Potential of Transferrin Glycoforms-A Lectin-Based Protein Microarray Approach.
    Penezić A; Križakova M; Miljuš G; Katrlik J; Nedić O
    Proteomics Clin Appl; 2019 Sep; 13(5):e1800185. PubMed ID: 31050875
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The Clinical Significance of Microsatellite Instability in Patients with Right-sided colorectal cancer.
    Han SA; Kim JH; Choi JH; Lee DH; Jung K; Kim SE; Moon W; Park MI; Park SJ
    Korean J Gastroenterol; 2019 Mar; 73(3):159-166. PubMed ID: 31013559
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