Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND KMT2A, TRX1, 4297, MLL, ENSG00000118058, MLL/GAS7, HTRX1, HRX, ALL-1, MLL1A, CXXC7 AND Treatment
25 results:

  • 1. Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in
    Jansen RA; Mainardi S; Dias MH; Bosma A; van Dijk E; Selig R; Albrecht W; Laufer SA; Zender L; Bernards R
    Proc Natl Acad Sci U S A; 2024 Feb; 121(9):e2319492121. PubMed ID: 38377196
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Nuclear translocation of thioredoxin-1 promotes colorectal cancer development via modulation of the IL-6/STAT3 signaling axis through interaction with STAT3.
    Wu A; Fang D; Liu Y; Shi X; Zhong Z; Zhou B; Ye L; Sun X; Jiang L
    Theranostics; 2023; 13(14):4730-4744. PubMed ID: 37771783
    [No Abstract]    [Full Text] [Related]  

  • 3. PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment.
    Ji G; Zhou W; Du J; Zhou J; Wu D; Zhao M; Yang L; Hao A
    Cell Death Dis; 2021 Jun; 12(7):633. PubMed ID: 34148069
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Advance care planning in patients with advanced cancer: A 6-country, cluster-randomised clinical trial.
    Korfage IJ; Carreras G; Arnfeldt Christensen CM; Billekens P; Bramley L; Briggs L; Bulli F; Caswell G; Červ B; van Delden JJM; Deliens L; Dunleavy L; Eecloo K; Gorini G; Groenvold M; Hammes B; Ingravallo F; Jabbarian LJ; Kars MC; Kodba-Čeh H; Lunder U; Miccinesi G; Mimić A; Ozbič P; Payne SA; Polinder S; Pollock K; Preston NJ; Seymour J; Simonič A; Thit Johnsen A; Toccafondi A; Verkissen MN; Wilcock A; Zwakman M; van der Heide A; Rietjens JAC
    PLoS Med; 2020 Nov; 17(11):e1003422. PubMed ID: 33186365
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. SOCS1 Represses Fractionated Ionizing Radiation-Induced EMT Signaling Pathways through the Counter-Regulation of ROS-Scavenging and ROS-Generating Systems.
    Kim S; Kim SH; Lee CE
    Cell Physiol Biochem; 2020 Oct; 54(5):1026-1040. PubMed ID: 33048478
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin.
    Wen C; Wang H; Wu X; He L; Zhou Q; Wang F; Chen S; Huang L; Chen J; Wang H; Ye W; Li W; Yang X; Liu H; Peng J
    Cell Death Dis; 2019 Oct; 10(11):809. PubMed ID: 31649256
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Impact of Patient Age on Molecular Alterations of Left-Sided colorectal Tumors.
    Puccini A; Lenz HJ; Marshall JL; Arguello D; Raghavan D; Korn WM; Weinberg BA; Poorman K; Heeke AL; Philip PA; Shields AF; Goldberg RM; Salem ME
    Oncologist; 2019 Mar; 24(3):319-326. PubMed ID: 30018131
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage.
    Neilsen BK; Chakraborty B; McCall JL; Frodyma DE; Sleightholm RL; Fisher KW; Lewis RE
    BMC Cancer; 2018 Jun; 18(1):673. PubMed ID: 29925347
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Thioredoxin-1 promotes colorectal cancer invasion and metastasis through crosstalk with S100P.
    Lin F; Zhang P; Zuo Z; Wang F; Bi R; Shang W; Wu A; Ye J; Li S; Sun X; Wu J; Jiang L
    Cancer Lett; 2017 Aug; 401():1-10. PubMed ID: 28483515
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy.
    Lou M; Liu Q; Ren G; Zeng J; Xiang X; Ding Y; Lin Q; Zhong T; Liu X; Zhu L; Qi H; Shen J; Li H; Shao J
    J Biol Chem; 2017 Jun; 292(22):9136-9149. PubMed ID: 28411237
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis.
    Dunnill CJ; Ibraheem K; Mohamed A; Southgate J; Georgopoulos NT
    Oncogene; 2017 May; 36(18):2515-2528. PubMed ID: 27869172
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation.
    Jung SH; Kim SM; Lee CE
    Oncotarget; 2016 Sep; 7(38):62559-62571. PubMed ID: 27613835
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Thioredoxin-1 inhibitor, 1-methylpropyl 2-imidazolyl disulfide, inhibits the growth, migration and invasion of colorectal cancer cell lines.
    Wang F; Lin F; Zhang P; Ni W; Bi L; Wu J; Jiang L
    Oncol Rep; 2015 Feb; 33(2):967-73. PubMed ID: 25483731
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Testing to prevent colon cancer: results from a rural community intervention.
    Westfall JM; Zittleman L; Sutter C; Emsermann CB; Staton EW; Van Vorst R; Dickinson LM;
    Ann Fam Med; 2013; 11(6):500-7. PubMed ID: 24218373
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Cediranib with mFOLFOX6 versus bevacizumab with mFOLFOX6 as first-line treatment for patients with advanced colorectal cancer: a double-blind, randomized phase III study (HORIZON III).
    Schmoll HJ; Cunningham D; Sobrero A; Karapetis CS; Rougier P; Koski SL; Kocakova I; Bondarenko I; Bodoky G; Mainwaring P; Salazar R; Barker P; Mookerjee B; Robertson J; Van Cutsem E
    J Clin Oncol; 2012 Oct; 30(29):3588-95. PubMed ID: 22965961
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Impact of short-course preoperative radiotherapy for rectal cancer on patients' quality of life: data from the Medical Research Council CR07/National cancer Institute of Canada Clinical Trials Group C016 randomized clinical trial.
    Stephens RJ; Thompson LC; Quirke P; Steele R; Grieve R; Couture J; Griffiths GO; Sebag-Montefiore D
    J Clin Oncol; 2010 Sep; 28(27):4233-9. PubMed ID: 20585099
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Effect of beta-carotene-rich tomato lycopene beta-cyclase ( tlcy-b) on cell growth inhibition in HT-29 colon adenocarcinoma cells.
    Palozza P; Bellovino D; Simone R; Boninsegna A; Cellini F; Monastra G; Gaetani S
    Br J Nutr; 2009 Jul; 102(2):207-14. PubMed ID: 19105854
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Diabetes mellitus and outcomes of colorectal cancer.
    Jullumstrø E; Kollind M; Lydersen S; Edna TH
    Acta Oncol; 2009; 48(3):361-7. PubMed ID: 19101848
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Acute myeloid leukaemia secondary to treatment with capecitabine for metastatic colorectal cancer.
    Shapiro S; Hughes G; Al-Obaidi MJ; O'Reilly E; Ramesh S; Smith J; Ahmad R; Dawson C; Riddle P; Sekhar M
    Eur J Haematol; 2007 Jun; 78(6):543-4. PubMed ID: 17509107
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Acceptance of neoadjuvant short-term radiotherapy: a survey under surgeons and radiotherapists.
    Ulrich A; Schwerdt J; Z'graggen K; Kienle P; Weitz J; Büchler MW
    Langenbecks Arch Surg; 2007 Sep; 392(5):525-33. PubMed ID: 17394012
    [TBL] [Abstract] [Full Text] [Related]  


    of 2.