Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND KMT2C, ENSG00000055609, MLL3, 58508
31 results:

  • 1. kmt2c mutation as a predictor of immunotherapeutic efficacy in colorectal cancer.
    Ni C; Wang X; Liu S; Zhang J; Luo Z; Xu B
    Sci Rep; 2024 Apr; 14(1):8284. PubMed ID: 38594266
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. A pair of primary colorectal cancer-derived and corresponding synchronous liver metastasis-derived organoid cell lines.
    Cheng F; Li P; Xu S; Zhang C; Liang H; Ding Z
    Aging (Albany NY); 2024 Feb; 16(5):4396-4422. PubMed ID: 38407980
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Clinicopathological characteristics, molecular landscape, and biomarker landscape for predicting the efficacy of PD-1/PD-L1 inhibitors in Chinese population with mismatch repair deficient urothelial carcinoma: a real-world study.
    Ma YT; Hua F; Zhong XM; Xue YJ; Li J; Nie YC; Zhang XD; Ma JW; Lin CH; Zhang HZ; He W; Sha D; Zhao MQ; Yao ZG
    Front Immunol; 2023; 14():1269097. PubMed ID: 38022513
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Sequencing paired tumor DNA and white blood cells improves circulating tumor DNA tracking and detects pathogenic germline variants in localized colon cancer.
    Gimeno-Valiente F; Martín-Arana J; Tébar-Martínez R; Gambardella V; Martínez-Ciarpaglini C; García-Micó B; Martínez-Castedo B; Palomar B; García-Bartolomé M; Seguí V; Huerta M; Moro-Valdezate D; Pla-Martí V; Pérez-Santiago L; Roselló S; Roda D; Cervantes A; Tarazona N
    ESMO Open; 2023 Dec; 8(6):102051. PubMed ID: 37951129
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Pathogenic alterations in PIK3CA and kmt2c are frequent and independent prognostic factors in anal squamous cell carcinoma treated with salvage abdominoperineal resection.
    Hamza A; Masliah-Planchon J; Neuzillet C; Lefèvre JH; Svrcek M; Vacher S; Bourneix C; Delaye M; Goéré D; Dartigues P; Samalin E; Hilmi M; Lazartigues J; Girard E; Emile JF; Rigault E; Dangles-Marie V; Rioux-Leclercq N; de la Fouchardière C; Tougeron D; Casadei-Gardini A; Mariani P; Peschaud F; Cacheux W; Lièvre A; Bièche I
    Int J Cancer; 2024 Feb; 154(3):504-515. PubMed ID: 37908048
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Deciphering Brain Metastasis Stem Cell Properties From colorectal cancer Highlights Specific Stemness Signature and Shared Molecular Features.
    Desette A; Guichet PO; Emambux S; Masliantsev K; Cortes U; Ndiaye B; Milin S; George S; Faigner M; Tisserand J; Gaillard A; Brot S; Wager M; Tougeron D; Karayan-Tapon L
    Cell Mol Gastroenterol Hepatol; 2023; 16(5):757-782. PubMed ID: 37482243
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Molecular typing and mutational characterization of rectal neuroendocrine neoplasms.
    Duan X; Zhao M; Yin X; Mi L; Shi J; Li N; Han X; Han G; Wang J; Hou J; Yin F
    Cancer Med; 2023 Aug; 12(15):16207-16220. PubMed ID: 37387515
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Comparison of genetic variation between primary colorectal cancer and metastatic peritoneal cancer.
    Shin W; Yun J; Han K; Park DG
    Genes Genomics; 2023 Aug; 45(8):989-1001. PubMed ID: 37277571
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Therapeutic targeting of metabolic vulnerabilities in cancers with mll3/4-COMPASS epigenetic regulator mutations.
    Zhao Z; Cao K; Watanabe J; Philips CN; Zeidner JM; Ishi Y; Wang Q; Gold SR; Junkins K; Bartom ET; Yue F; Chandel NS; Hashizume R; Ben-Sahra I; Shilatifard A
    J Clin Invest; 2023 Jul; 133(13):. PubMed ID: 37252797
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Genomic characteristics and prognosis of lung cancer patients with MSI-H: A cohort study.
    Tian J; Wang H; Lu C; Liu L; Zhang X; Xie Y; Li R; Lv X; Fu D; Zhang L; Fang X; Wang X; Hu J; Liu X; Huang X; Zhao Q; Luo N; Tang H; Zhong Z; He Y; Li L
    Lung Cancer; 2023 Jul; 181():107255. PubMed ID: 37244039
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. PGNneo: A Proteogenomics-Based Neoantigen Prediction Pipeline in Noncoding Regions.
    Tan X; Xu L; Jian X; Ouyang J; Hu B; Yang X; Wang T; Xie L
    Cells; 2023 Mar; 12(5):. PubMed ID: 36899918
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Association of kmt2c/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.
    Liu R; Niu Y; Liu C; Zhang X; Zhang J; Shi M; Zou W; Gu B; Zhu H; Wang D; Yuan H; Li W; Zhao D; Zheng Q; Liu R; Chen W; Ma T; Zhang Y
    Cancer Sci; 2023 Apr; 114(4):1229-1239. PubMed ID: 36601880
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Restoration of kmt2c/mll3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression.
    Larsson C; Cordeddu L; Siggens L; Pandzic T; Kundu S; He L; Ali MA; Pristovšek N; Hartman K; Ekwall K; Sjöblom T
    Clin Epigenetics; 2020 May; 12(1):74. PubMed ID: 32471474
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. cancer-derived UTX TPR mutations G137V and D336G impair interaction with mll3/4 complexes and affect UTX subcellular localization.
    Kato H; Asamitsu K; Sun W; Kitajima S; Yoshizawa-Sugata N; Okamoto T; Masai H; Poellinger L
    Oncogene; 2020 Apr; 39(16):3322-3335. PubMed ID: 32071397
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Impact of Patient Age on Molecular Alterations of Left-Sided colorectal Tumors.
    Puccini A; Lenz HJ; Marshall JL; Arguello D; Raghavan D; Korn WM; Weinberg BA; Poorman K; Heeke AL; Philip PA; Shields AF; Goldberg RM; Salem ME
    Oncologist; 2019 Mar; 24(3):319-326. PubMed ID: 30018131
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4.
    Rahnamoun H; Hong J; Sun Z; Lee J; Lu H; Lauberth SM
    J Biol Chem; 2018 Aug; 293(34):13234-13246. PubMed ID: 29954944
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Uncommon somatic mutations in metastatic NUT midline carcinoma.
    Cavalieri S; Stathis A; Fabbri A; Sonzogni A; Perrone F; Tamborini E; Pelosi G; de Braud F; Platania M
    Tumori; 2017 Nov; 103(Suppl. 1):e5-e8. PubMed ID: 28967088
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Mutational Landscapes of Smoking-Related cancers in Caucasians and African Americans: Precision Oncology Perspectives at Wake Forest Baptist Comprehensive cancer Center.
    Kytola V; Topaloglu U; Miller LD; Bitting RL; Goodman MM; D Agostino RB; Desnoyers RJ; Albright C; Yacoub G; Qasem SA; DeYoung B; Thorsson V; Shmulevich I; Yang M; Shcherban A; Pagni M; Liu L; Nykter M; Chen K; Hawkins GA; Grant SC; Petty WJ; Alistar AT; Levine EA; Staren ED; Langefeld CD; Miller V; Singal G; Petro RM; Robinson M; Blackstock W; Powell BL; Wagner LI; Foley KL; Abraham E; Pasche B; Zhang W
    Theranostics; 2017; 7(11):2914-2923. PubMed ID: 28824725
    [No Abstract]    [Full Text] [Related]  

  • 19. Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal.
    Morris V; Rao X; Pickering C; Foo WC; Rashid A; Eterovic K; Kim T; Chen K; Wang J; Shaw K; Eng C
    Mol Cancer Res; 2017 Nov; 15(11):1542-1550. PubMed ID: 28784613
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
    Chakrabarty S; Varghese VK; Sahu P; Jayaram P; Shivakumar BM; Pai CG; Satyamoorthy K
    Br J Cancer; 2017 Jun; 117(1):136-143. PubMed ID: 28524162
    [TBL] [Abstract] [Full Text] [Related]  


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