Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1 AND Treatment
6 results:

  • 1. Small-molecule inhibition of map2k4 is synergistic with RAS inhibitors in
    Jansen RA; Mainardi S; Dias MH; Bosma A; van Dijk E; Selig R; Albrecht W; Laufer SA; Zender L; Bernards R
    Proc Natl Acad Sci U S A; 2024 Feb; 121(9):e2319492121. PubMed ID: 38377196
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study.
    Wang J; Xiu J; Farrell A; Baca Y; Arai H; Battaglin F; Kawanishi N; Soni S; Zhang W; Millstein J; Shields AF; Grothey A; Weinberg BA; Marshall JL; Lou E; Khushman M; Sohal DPS; Hall MJ; Liu T; Oberley M; Spetzler D; Korn WM; Shen L; Lenz HJ
    Lancet Oncol; 2023 Feb; 24(2):151-161. PubMed ID: 36681091
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Protein kinase p38α signaling in dendritic cells regulates colon inflammation and tumorigenesis.
    Zheng T; Zhang B; Chen C; Ma J; Meng D; Huang J; Hu R; Liu X; Otsu K; Liu AC; Li H; Yin Z; Huang G
    Proc Natl Acad Sci U S A; 2018 Dec; 115(52):E12313-E12322. PubMed ID: 30541887
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis.
    Dunnill CJ; Ibraheem K; Mohamed A; Southgate J; Georgopoulos NT
    Oncogene; 2017 May; 36(18):2515-2528. PubMed ID: 27869172
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients.
    Guinney J; Ferté C; Dry J; McEwen R; Manceau G; Kao KJ; Chang KM; Bendtsen C; Hudson K; Huang E; Dougherty B; Ducreux M; Soria JC; Friend S; Derry J; Laurent-Puig P
    Clin Cancer Res; 2014 Jan; 20(1):265-272. PubMed ID: 24170544
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. MAP kinases in proliferating human colon cancer Caco-2 cells.
    Buzzi N; Colicheo A; Boland R; de Boland AR
    Mol Cell Biochem; 2009 Aug; 328(1-2):201-8. PubMed ID: 19301097
    [TBL] [Abstract] [Full Text] [Related]  

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