Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND MAP3K1, ENSG00000095015, 4214, Q13233, MEKK1, MEKK, MAPKKK1
21 results:

  • 1. Whole exome sequencing identifies map3k1, MSH2, and MLH1 as potential cancer-predisposing genes in familial early-onset colorectal cancer.
    Fatemi N; Tu SJ; Chung CC; Moghadam PK; Mojarad EN; Sadeghi A; Totonchi M; Aghdaei HA; Chang JG
    Kaohsiung J Med Sci; 2023 Sep; 39(9):896-903. PubMed ID: 37314251
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Circ_0085315 promotes cell proliferation, invasion, and migration in colon cancer through miR-1200/map3k1 signaling pathway.
    Luo Y; Yao Q
    Cell Cycle; 2022 Jun; 21(11):1194-1211. PubMed ID: 35230926
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. RNA-binding protein IMP3 is a novel regulator of MEK1/ERK signaling pathway in the progression of colorectal cancer through the stabilization of mekk1 mRNA.
    Zhang M; Zhao S; Tan C; Gu Y; He X; Du X; Li D; Wei P
    J Exp Clin Cancer Res; 2021 Jun; 40(1):200. PubMed ID: 34154626
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Impact of obesity on short-term outcomes of laparoscopic colorectal surgery for Japanese patients with colorectal cancer: A multicenter study.
    Yamashita M; Tominaga T; Nonaka T; Fukda A; Moriyama M; Oyama S; Tanaka K; Hamada K; Araki M; Sumida Y; Takeshita H; Hisanaga M; Fukuoka H; Wada H; Tou K; Sawai T; Nagayasu T
    Asian J Endosc Surg; 2021 Jul; 14(3):432-442. PubMed ID: 33111467
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Expression of the human antimicrobial peptide β-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells.
    Bonamy C; Sechet E; Amiot A; Alam A; Mourez M; Fraisse L; Sansonetti PJ; Sperandio B
    Sci Rep; 2018 Dec; 8(1):18043. PubMed ID: 30575780
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. map3k1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.
    Xue Z; Vis DJ; Bruna A; Sustic T; van Wageningen S; Batra AS; Rueda OM; Bosdriesz E; Caldas C; Wessels LFA; Bernards R
    Cell Res; 2018 Jul; 28(7):719-729. PubMed ID: 29795445
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Identification of genetic variants for clinical management of familial colorectal tumors.
    Dominguez-Valentin M; Nakken S; Tubeuf H; Vodak D; Ekstrøm PO; Nissen AM; Morak M; Holinski-Feder E; Martins A; Møller P; Hovig E
    BMC Med Genet; 2018 Feb; 19(1):26. PubMed ID: 29458332
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Impact of genetic variations in the MAPK signaling pathway on outcome in metastatic colorectal cancer patients treated with first-line FOLFIRI and bevacizumab: data from FIRE-3 and TRIBE trials.
    Berger MD; Stintzing S; Heinemann V; Yang D; Cao S; Sunakawa Y; Ning Y; Matsusaka S; Okazaki S; Miyamoto Y; Suenaga M; Schirripa M; Soni S; Zhang W; Falcone A; Loupakis F; Lenz HJ
    Ann Oncol; 2017 Nov; 28(11):2780-2785. PubMed ID: 29045529
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. MTDH and map3k1 are direct targets of apoptosis-regulating miRNAs in colorectal carcinoma.
    Salem SM; Hamed AR; Mosaad RM
    Biomed Pharmacother; 2017 Oct; 94():767-773. PubMed ID: 28802228
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Effects of parafibromin expression on the phenotypes and relevant mechanisms in the DLD-1 colon carcinoma cell line.
    Zhao S; Sun HZ; Zhu ST; Lu H; Niu ZF; Guo WF; Takano Y; Zheng HC
    Asian Pac J Cancer Prev; 2013; 14(7):4249-54. PubMed ID: 23991985
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Dietary influence on MAPK-signaling pathways and risk of colon and rectal cancer.
    Slattery ML; Lundgreen A; Wolff RK
    Nutr Cancer; 2013; 65(5):729-38. PubMed ID: 23859041
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. MAP kinase genes and colon and rectal cancer.
    Slattery ML; Lundgreen A; Wolff RK
    Carcinogenesis; 2012 Dec; 33(12):2398-408. PubMed ID: 23027623
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis.
    Zhang H; Hao Y; Yang J; Zhou Y; Li J; Yin S; Sun C; Ma M; Huang Y; Xi JJ
    Nat Commun; 2011 Nov; 2():554. PubMed ID: 22109528
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Racial variation in willingness to trade financial resources for life-prolonging cancer treatment.
    Martin MY; Pisu M; Oster RA; Urmie JM; Schrag D; Huskamp HA; Lee J; Kiefe CI; Fouad MN
    Cancer; 2011 Aug; 117(15):3476-84. PubMed ID: 21523759
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. map3k1 functionally interacts with Axin1 in the canonical Wnt signalling pathway.
    Sue Ng S; Mahmoudi T; Li VSW; Hatzis P; Boersema PJ; Mohammed S; Heck AJ; Clevers H
    Biol Chem; 2010; 391(2-3):171-180. PubMed ID: 20128690
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Expression of CARD6, an NF-kappaB activator, in gastric, colorectal and oesophageal cancers.
    Kim SS; Ahn CH; Kang MR; Kim YR; Kim HS; Yoo NJ; Lee SH
    Pathology; 2010 Jan; 42(1):50-3. PubMed ID: 20025480
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Ethnic disparity in mortality after diagnosis of colorectal cancer among inner city minority New Yorkers.
    Kanna B; Narang TK; Atwal T; Paul D; Azeez S
    Cancer; 2009 Dec; 115(23):5550-5. PubMed ID: 19823980
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Alternative activation of extracellular signal-regulated protein kinases in curcumin and arsenite-induced HSP70 gene expression in human colorectal carcinoma cells.
    Chen YC; Tsai SH; Shen SC; Lin JK; Lee WR
    Eur J Cell Biol; 2001 Mar; 80(3):213-21. PubMed ID: 11322385
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.
    Soh JW; Mao Y; Kim MG; Pamukcu R; Li H; Piazza GA; Thompson WJ; Weinstein IB
    Clin Cancer Res; 2000 Oct; 6(10):4136-41. PubMed ID: 11051267
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Regulation of FasL by NF-kappaB and AP-1 in Fas-dependent thymineless death of human colon carcinoma cells.
    Harwood FG; Kasibhatla S; Petak I; Vernes R; Green DR; Houghton JA
    J Biol Chem; 2000 Apr; 275(14):10023-9. PubMed ID: 10744679
    [TBL] [Abstract] [Full Text] [Related]  


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