Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND MAPK1, MAPK2, 5594, ENSG00000100030, P28482, ERK2, p40, PRKM1, p38, p41, ERT1, p41mapk, PRKM2, P42MAPK, ERK AND Clinical Outcome
16 results:

  • 1. colorectal adenosquamous carcinoma: Peculiar morphologic features and distinct immunoprofiles in squamous and glandular components.
    Parente P; Mastracci L; Vanoli A; Businello G; Paudice M; Angerilli V; Castelvetere M; Graziano P; Fassan M; Grillo F
    Pathol Res Pract; 2022 Aug; 236():153967. PubMed ID: 35662040
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. AZ304, a novel dual BRAF inhibitor, exerts anti-tumour effects in colorectal cancer independently of BRAF genetic status.
    Ma R; Xu L; Qu X; Che X; Zhang Y; Fan Y; Li C; Guo T; Hou K; Hu X; Drew L; Shen M; Cheung T; Liu Y
    Br J Cancer; 2018 May; 118(11):1453-1463. PubMed ID: 29755114
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in
    Hazar-Rethinam M; Kleyman M; Han GC; Liu D; Ahronian LG; Shahzade HA; Chen L; Parikh AR; Allen JN; Clark JW; Kwak EL; Faris JE; Murphy JE; Hong TS; Van Seventer EE; Nadres B; Hong CB; Gurski JM; Jessop NA; Dias-Santagata D; Iafrate AJ; Van Allen EM; Corcoran RB
    Cancer Discov; 2018 Apr; 8(4):417-427. PubMed ID: 29431697
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent erk signaling.
    Liu H; Zhang Q; Li K; Gong Z; Liu Z; Xu Y; Swaney MH; Xiao K; Chen Y
    Oncotarget; 2016 Dec; 7(49):81223-81240. PubMed ID: 27835898
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Cytotoxicity of PEGylated liposomes co-loaded with novel pro-apoptotic drug NCL-240 and the MEK inhibitor cobimetinib against colon carcinoma in vitro.
    Sriraman SK; Geraldo V; Luther E; Degterev A; Torchilin V
    J Control Release; 2015 Dec; 220(Pt A):160-168. PubMed ID: 26497930
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Protein phosphatase methylesterase-1 (PME-1) expression predicts a favorable clinical outcome in colorectal cancer.
    Kaur A; Elzagheid A; Birkman EM; Avoranta T; Kytölä V; Korkeila E; Syrjänen K; Westermarck J; Sundström J
    Cancer Med; 2015 Dec; 4(12):1798-808. PubMed ID: 26377365
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Co-existence of BRAF V600E Gene Mutation in Tumor and Non-tumoral Surrounding Tissues in colorectal cancer.
    Öztürk T; Toptaş-Hekimoğlu B; Eronat AP; Saygili N; Dağlar-Aday A; Başsüllü N; Türkmen I; Aydoğan HY; Bülbül G; Göksel S; Öztürk O; Isbir T
    In Vivo; 2015; 29(5):577-84. PubMed ID: 26359417
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. ErbB-3 activation by NRG-1β sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs).
    Prasetyanti PR; Capone E; Barcaroli D; D'Agostino D; Volpe S; Benfante A; van Hooff S; Iacobelli V; Rossi C; Iacobelli S; Medema JP; De Laurenzi V; Sala G
    Oncotarget; 2015 Jul; 6(19):16902-11. PubMed ID: 26160848
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.
    Depeille P; Henricks LM; van de Ven RA; Lemmens E; Wang CY; Matli M; Werb Z; Haigis KM; Donner D; Warren R; Roose JP
    Nat Cell Biol; 2015 Jun; 17(6):804-15. PubMed ID: 26005835
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Implication of metastasis suppressor gene, Kiss-1 and its receptor Kiss-1R in colorectal cancer.
    Ji K; Ye L; Ruge F; Hargest R; Mason MD; Jiang WG
    BMC Cancer; 2014 Sep; 14():723. PubMed ID: 25260785
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. TRAP1 is involved in BRAF regulation and downstream attenuation of erk phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors.
    Condelli V; Piscazzi A; Sisinni L; Matassa DS; Maddalena F; Lettini G; Simeon V; Palladino G; Amoroso MR; Trino S; Esposito F; Landriscina M
    Cancer Res; 2014 Nov; 74(22):6693-704. PubMed ID: 25239454
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Is biomarker research advancing in the era of personalized medicine for head and neck cancer?
    Yokota T
    Int J Clin Oncol; 2014 Apr; 19(2):211-9. PubMed ID: 24442754
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression.
    Wang Y; Velho S; Vakiani E; Peng S; Bass AJ; Chu GC; Gierut J; Bugni JM; Der CJ; Philips M; Solit DB; Haigis KM
    Cancer Discov; 2013 Mar; 3(3):294-307. PubMed ID: 23274911
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients.
    Vlajnic T; Andreozzi MC; Schneider S; Tornillo L; Karamitopoulou E; Lugli A; Ruiz C; Zlobec I; Terracciano L
    Mod Pathol; 2011 Oct; 24(10):1404-12. PubMed ID: 21743435
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. erk signaling in colorectal cancer: a preliminary report on the expression of phosphorylated erk and the effects of radiation therapy.
    Corn BW; Kovner F; Bek S; Wexler I; Lifschits B; Seger R
    Am J Clin Oncol; 2008 Jun; 31(3):255-8. PubMed ID: 18525304
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced erk-1 and -2 and HIF-1alpha induction pathway.
    Calviello G; Di Nicuolo F; Gragnoli S; Piccioni E; Serini S; Maggiano N; Tringali G; Navarra P; Ranelletti FO; Palozza P
    Carcinogenesis; 2004 Dec; 25(12):2303-10. PubMed ID: 15358633
    [TBL] [Abstract] [Full Text] [Related]  

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