Terms: = Colorectal cancer AND MAPK1, MAPK2, 5594, ENSG00000100030, P28482, ERK2, p40, PRKM1, p38, p41, ERT1, p41mapk, PRKM2, P42MAPK, ERK AND Treatment
911 results:
1. Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, erk1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status.
Zhang J; Zhou L; Zhao S; El-Deiry WS
Oncotarget; 2024 Jul; 15():424-438. PubMed ID: 38953895
[TBL] [Abstract] [Full Text] [Related]
2. Cholestasis-induced phenotypic transformation of neutrophils contributes to immune escape of colorectal cancer liver metastasis.
Sun L; Yang N; Liu Z; Ye X; Cheng M; Deng L; Zhang J; Wu J; Shi M; Liao W
J Biomed Sci; 2024 Jun; 31(1):66. PubMed ID: 38951890
[TBL] [Abstract] [Full Text] [Related]
3. erk Inhibition as a Promising Therapeutic Strategy for High IL-8-Secreting and Low SPTAN1-Expressing colorectal cancer.
Meier C; La Rocca G; Nawrot V; Fißlthaler B; Overby SJ; Hourfar K; Plotz G; Seidl C; Ziegler P; Wild P; Zeuzem S; Brieger J; Jäger E; Battmann A; Brieger A
Int J Mol Sci; 2024 May; 25(11):. PubMed ID: 38891846
[TBL] [Abstract] [Full Text] [Related]
4. Antitumor activity of dictamnine against colorectal cancer through induction of ferroptosis and inhibition of M2 macrophage polarization via the MAPK signaling.
Zuo X; Lin H; Song Z; Yu B; Zhao C
Arch Biochem Biophys; 2024 Aug; 758():110051. PubMed ID: 38851368
[TBL] [Abstract] [Full Text] [Related]
5. A Novel Photosensitizer Based 450-nm Blue Laser-Mediated Photodynamic Therapy Induces Apoptosis in colorectal cancer -
Mei Y; Gu L; Chen Y; Zhang P; Cheng Y; Yuan R; Li X; Wang X; Guo P; He D; Zeng J
Front Biosci (Landmark Ed); 2024 May; 29(5):199. PubMed ID: 38812322
[TBL] [Abstract] [Full Text] [Related]
6. Casearia sylvestris var. lingua (Càmbess.) Eichler leaves aqueous extract improves colon inflammation through mucogenic, antioxidant and anti-inflammatory actions in TNBS- induced IBD rats.
Arunachalam K; Matchado MS; Damazo AS; Cardoso CAL; Castro TLA; Baranoski A; Neves SCD; Martins DTO; Nascimento VAD; Oliveira RJ
J Ethnopharmacol; 2024 Oct; 332():118393. PubMed ID: 38801913
[TBL] [Abstract] [Full Text] [Related]
7. PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in colorectal cancer.
Huang ZJ; Li YJ; Yang J; Huang L; Zhao Q; Lu YF; Hu Y; Zhang WX; Liang JZ; Pan J; Pan YL; He QY; Wang Y
Int J Biol Sci; 2024; 20(6):2202-2218. PubMed ID: 38617530
[TBL] [Abstract] [Full Text] [Related]
8. Structure-Guided Discovery and Preclinical Assessment of Novel (Thiophen-3-yl)aminopyrimidine Derivatives as Potent erk1/2 Inhibitors.
Shuai W; Xiao H; Yang P; Zhang Y; Bu F; Wu Y; Sun Q; Wang G; Ouyang L
J Med Chem; 2024 Apr; 67(8):6425-6455. PubMed ID: 38613499
[TBL] [Abstract] [Full Text] [Related]
9. The Natural Product Secoemestrin C Inhibits colorectal cancer Stem Cells via p38-S100A8 Feed-Forward Regulatory Loop.
Zhou H; Chen M; Zhao C; Shao R; Xu Y; Zhao W
Cells; 2024 Apr; 13(7):. PubMed ID: 38607060
[TBL] [Abstract] [Full Text] [Related]
10. Interleukin-12: Structure, Function, and Its Impact in colorectal cancer.
Zhu Z; Peng Q; Duan X; Li J
J Interferon Cytokine Res; 2024 Apr; 44(4):158-169. PubMed ID: 38498032
[TBL] [Abstract] [Full Text] [Related]
11. Role of deubiquitinase JOSD2 in the pathogenesis of esophageal squamous cell carcinoma.
Wang WP; Shi D; Yun D; Hu J; Wang JF; Liu J; Yang YP; Li MR; Wang JF; Kong DL
World J Gastroenterol; 2024 Feb; 30(6):565-578. PubMed ID: 38463028
[TBL] [Abstract] [Full Text] [Related]
12. Peptide mimetic NC114 induces growth arrest by preventing PKCδ activation and FOXM1 nuclear translocation in colorectal cancer cells.
Taguchi Y; Nakaya T; Aizawa K; Noguchi Y; Maiya N; Iwamoto C; Ohba K; Sugawara M; Murata M; Nagai R; Kano F
FEBS Open Bio; 2024 Apr; 14(4):695-720. PubMed ID: 38425293
[TBL] [Abstract] [Full Text] [Related]
13. Fusobacterium nucleatum promotes tumor progression in KRAS p.G12D-mutant colorectal cancer by binding to DHX15.
Zhu H; Li M; Bi D; Yang H; Gao Y; Song F; Zheng J; Xie R; Zhang Y; Liu H; Yan X; Kong C; Zhu Y; Xu Q; Wei Q; Qin H
Nat Commun; 2024 Feb; 15(1):1688. PubMed ID: 38402201
[TBL] [Abstract] [Full Text] [Related]
14. A growth factor-reduced culture system for colorectal cancer organoids.
Tan R; Zhang Z; Ding P; Liu Y; Liu H; Lu M; Chen YG
Cancer Lett; 2024 Apr; 588():216737. PubMed ID: 38382667
[TBL] [Abstract] [Full Text] [Related]
15. Caffeic acid phenethyl ester mediates apoptosis in serum-starved HT29 colon cancer cells through modulation of heat shock proteins and MAPK pathways.
Yahya S; Sulaiman MK; Sudhandiran G
Cell Biochem Funct; 2024 Mar; 42(2):e3942. PubMed ID: 38379263
[TBL] [Abstract] [Full Text] [Related]
16. Targeting MEK/COX-2 axis improve immunotherapy efficacy in dMMR colorectal cancer with PIK3CA overexpression.
Peng K; Liu Y; Liu S; Wang Z; Zhang H; He W; Jin Y; Wang L; Xia X; Xia L
Cell Oncol (Dordr); 2024 Jun; 47(3):1043-1058. PubMed ID: 38315285
[TBL] [Abstract] [Full Text] [Related]
17. Platycodin D induces apoptosis via regulating MAPK pathway and promotes autophagy in colon cancer cell.
Han SH; Lee JH; Woo JS; Jung GH; Jung SH; Han EJ; Park YS; Kim BS; Kim SK; Park BK; Jung JY
Biomed Pharmacother; 2024 Mar; 172():116216. PubMed ID: 38295755
[TBL] [Abstract] [Full Text] [Related]
18. Collagen I-induced VCAN/erk signaling and PARP1/ZEB1-mediated metastasis facilitate OSBPL2 defect to promote colorectal cancer progression.
Lin K; Zhao Y; Tang Y; Chen Y; Lin M; He L
Cell Death Dis; 2024 Jan; 15(1):85. PubMed ID: 38267463
[TBL] [Abstract] [Full Text] [Related]
19. c-Fos regulated by TMPO/erk axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer.
Gui Y; Qian X; Ding Y; Chen Q; Fangyu Ye ; Ye Y; Hou Y; Yu J; Zhao L
Cell Death Dis; 2024 Jan; 15(1):61. PubMed ID: 38233377
[TBL] [Abstract] [Full Text] [Related]
20. KLF7 promotes colon adenocarcinoma progression through the PDGFB signaling pathway.
Zhang Z; Jiang X; Li K; Qiao S; Li M; Mei Y; Ding L; Lv Q; Ding Y; Zhao Y; Lv G; Tan G; Yang H; Li G; Gao X; Liu M
Int J Biol Sci; 2024; 20(1):387-402. PubMed ID: 38164176
[TBL] [Abstract] [Full Text] [Related]
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