Terms: = Colorectal cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987
354 results:
1. Working title: Molecular involvement of p53-mdm2 interactome in gastrointestinal cancers.
Yedla P; Bhamidipati P; Syed R; Amanchy R
Cell Biochem Funct; 2024 Jun; 42(4):e4075. PubMed ID: 38924101
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2. USP11 modulates mitotic progression and senescence by regulating the p53-p21 axis through mdm2 deubiquitination.
Kim WJ; Basit A; Lee JH
Biochem Biophys Res Commun; 2024 Sep; 726():150275. PubMed ID: 38901057
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3. Therapeutic targeting of ARID1A-deficient cancer cells with RITA (Reactivating p53 and inducing tumor apoptosis).
Wang Z; Zhang X; Luo Y; Song Y; Xiang C; He Y; Wang K; Yu Y; Wang Z; Peng W; Ding Y; Liu S; Wu C
Cell Death Dis; 2024 May; 15(5):375. PubMed ID: 38811536
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4. Helminth-derived molecules improve 5-fluorouracil treatment on experimental colon tumorigenesis.
Mendoza-Rodríguez MG; Medina-Reyes D; Sánchez-Barrera CA; Fernández-Muñoz KV; García-Castillo V; Ledesma-Torres JL; González-González MI; Reyes JL; Pérez-Plascencia C; Rodríguez-Sosa M; Vaca-Paniagua F; Meraz MA; Terrazas LI
Biomed Pharmacother; 2024 Jun; 175():116628. PubMed ID: 38663106
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5. Nanoencapsulation of mdm2 Inhibitor RG7388 and Class-I HDAC Inhibitor Entinostat Enhances their Therapeutic Potential Through Synergistic Antitumor Effects and Reduction of Systemic Toxicity.
Abed A; Greene MK; Alsa'd AA; Lees A; Hindley A; Longley DB; McDade SS; Scott CJ
Mol Pharm; 2024 Mar; 21(3):1246-1255. PubMed ID: 38334409
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6. Development and Nanoparticle-Mediated Delivery of Novel mdm2/MDM4 Heterodimer Peptide Inhibitors to Enhance 5-Fluorouracil Nucleolar Stress in colorectal cancer Cells.
Merlino F; Pecoraro A; Longobardi G; Donati G; Di Leva FS; Brignola C; Piccarducci R; Daniele S; Martini C; Marinelli L; Russo G; Quaglia F; Conte C; Russo A; La Pietra V
J Med Chem; 2024 Feb; 67(3):1812-1824. PubMed ID: 38285632
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7. LC-HRMS Profiling and Cytotoxic Potential of Actinomycetes Associated with the Red Sea Soft Coral Sarcophyton glaucum: In vitro and In silico Studies.
El-Hawary SS; Hassan MHA; Hudhud AO; Al-Karmalawy AA; Mustafa M; Hamed EAE; Abdelmohsen UR; Mohammed R
Chem Biodivers; 2024 Mar; 21(3):e202301617. PubMed ID: 38193652
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8. Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma.
Mohamed MF; Ibrahim NS; Saddiq AA; Abdelhamid IA
Sci Rep; 2023 Dec; 13(1):22486. PubMed ID: 38110432
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9. Characteristic Mutational Damages in Gastric and colorectal Adenocarcinomas.
Yermekova S; Orazgaliyeva M; Goncharova T; Rakhimbekova F; Kaidarova D; Shatkovskaya O
Asian Pac J Cancer Prev; 2023 Nov; 24(11):3939-3947. PubMed ID: 38019254
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10. Pathway-driven analysis of synthetic lethal interactions in cancer using perturbation screens.
Karimpour M; Totonchi M; Behmanesh M; Montazeri H
Life Sci Alliance; 2024 Jan; 7(1):. PubMed ID: 37863651
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11. CLDN6 inhibits colorectal cancer proliferation dependent on restraining p53 ubiquitination via ZO-1/PTEN axis.
Dong Y; Xu W; Qi D; Qu H; Jin Q; Sun M; Wang X; Quan C
Cell Signal; 2023 Dec; 112():110930. PubMed ID: 37852424
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12. New Schiff bases derived from dimethylpyridine-1,2,4-triazole hybrid as cytotoxic agents targeting gastrointestinal cancers: Design, synthesis, biological evaluation and molecular docking studies.
Strzelecka M; Wiatrak B; Jawień P; Czyżnikowska Ż; Świątek P
Bioorg Chem; 2023 Oct; 139():106758. PubMed ID: 37540951
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13. Swietenolide isolated from
Pal PC; Nag S; Jyothi D; Das S; Saha KD; Singh UP
Nat Prod Res; 2024 Jun; 38(12):2097-2104. PubMed ID: 37450037
[No Abstract] [Full Text] [Related]
14. Bilirubin, an endogenous antioxidant that affects p53 protein and its downstream apoptosis/autophagy-related genes in LS180 and SW480 cell culture models of colorectal cancer.
Niknam M; Maleki MH; Khakshournia S; Rasouli M; Vakili O; Shafiee SM
Biochem Biophys Res Commun; 2023 Sep; 672():161-167. PubMed ID: 37354609
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15. P53/mdm2 Complex-Based Targeted Strategies in Colon Adenocarcinoma.
Niotis A; Tsiambas E; Dimitroulis D; Sarlanis H; Falidas E; Kavantzas N; Constantinides CA
Acta Med Acad; 2023 Apr; 52(1):24-29. PubMed ID: 37326394
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16. The crosstalk between ubiquitin-conjugating enzyme E2Q1 and p53 in colorectal cancer: An in vitro analysis.
Rasouli M; Khakshournia S; Vakili O; Dastghaib S; Seghatoleslam A; Shafiee SM
Med Oncol; 2023 Jun; 40(7):199. PubMed ID: 37294480
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17. Spatial resolution of cellular senescence dynamics in human colorectal liver metastasis.
Garbarino O; Lambroia L; Basso G; Marrella V; Franceschini B; Soldani C; Pasqualini F; Giuliano D; Costa G; Peano C; Barbarossa D; Annarita D; Salvati A; Terracciano L; Torzilli G; Donadon M; Faggioli F
Aging Cell; 2023 Jul; 22(7):e13853. PubMed ID: 37157887
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18. LIM domain-containing protein Ajuba inhibits chemotherapy-induced apoptosis by negatively regulating p53 stability in colorectal cancer cells.
Xu B; Li Q; Zhang J; Chen F
Mol Oncol; 2023 Aug; 17(8):1678-1691. PubMed ID: 36931700
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19. Inclusion of Nitrofurantoin into the Realm of cancer Chemotherapy via Biology-Oriented Synthesis and Drug Repurposing.
Elzahhar PA; Nematalla HA; Al-Koussa H; Abrahamian C; El-Yazbi AF; Bodgi L; Bou-Gharios J; Azzi J; Al Choboq J; Labib HF; Kheir WA; Abu-Serie MM; Elrewiny MA; El-Yazbi AF; Belal ASF
J Med Chem; 2023 Apr; 66(7):4565-4587. PubMed ID: 36921275
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20. CopA3 peptide inhibits mdm2-p53 complex stability in colorectal cancers and activates p53 mediated cell death machinery.
Dey DK; Sharma C; Vadlamudi Y; Kang SC
Life Sci; 2023 Apr; 318():121476. PubMed ID: 36758667
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