Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Prognosis
41 results:

  • 1. CLDN6 inhibits colorectal cancer proliferation dependent on restraining p53 ubiquitination via ZO-1/PTEN axis.
    Dong Y; Xu W; Qi D; Qu H; Jin Q; Sun M; Wang X; Quan C
    Cell Signal; 2023 Dec; 112():110930. PubMed ID: 37852424
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. The c-MYC-WDR43 signalling axis promotes chemoresistance and tumour growth in colorectal cancer by inhibiting p53 activity.
    Di Y; Jing X; Hu K; Wen X; Ye L; Zhang X; Qin J; Ye J; Lin R; Wang Z; He W
    Drug Resist Updat; 2023 Jan; 66():100909. PubMed ID: 36525936
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP2.
    Chen Y; Zhou S; Wan K; Yu L; Zhao C; Deng H; Ou Q; Qin J; Hu J; Hou Z
    Oncogene; 2022 Jun; 41(25):3433-3444. PubMed ID: 35589951
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  • 4. Downregulation of CPT2 promotes proliferation and inhibits apoptosis through p53 pathway in colorectal cancer.
    Liu F; Li X; Yan H; Wu J; Yang Y; He J; Chen J; Jiang Z; Wu F; Jiang Z
    Cell Signal; 2022 Apr; 92():110267. PubMed ID: 35108639
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Choline-induced SLC5A7 impairs colorectal cancer growth by stabilizing p53 protein.
    Yin Y; Jiang Z; Fu J; Li Y; Fang C; Yin X; Chen Y; Chen N; Li J; Ji Y; Su X; Qiu M; Huang W; Zhang B; Deng H; Dai L
    Cancer Lett; 2022 Jan; 525():55-66. PubMed ID: 34562520
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  • 6. Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP.
    Chen Y; Hao Q; Wang S; Cao M; Huang Y; Weng X; Wang J; Zhang Z; He X; Lu H; Zhou X
    Proc Natl Acad Sci U S A; 2021 Jul; 118(29):. PubMed ID: 34266953
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Cullin-4B promotes cell proliferation and invasion through inactivation of p53 signaling pathway in colorectal cancer.
    Zhong M; Zhou L; Zou J; He Y; Fang Z; Xiang X
    Pathol Res Pract; 2021 Aug; 224():153520. PubMed ID: 34153655
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53.
    Wang W; Wei J; Zhang H; Zheng X; Zhou H; Luo Y; Yang J; Deng Q; Huang S; Fu Z
    Cell Death Dis; 2021 Jun; 12(6):605. PubMed ID: 34117220
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Synergisms of genome and metabolism stabilizing antitumor therapy (GMSAT) in human breast and colon cancer cell lines: a novel approach to screen for synergism.
    Ruhnau J; Parczyk J; Danker K; Eickholt B; Klein A
    BMC Cancer; 2020 Jul; 20(1):617. PubMed ID: 32615946
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Roles of DANCR/microRNA-518a-3p/MDMA ceRNA network in the growth and malignant behaviors of colon cancer cells.
    Sun Y; Cao B; Zhou J
    BMC Cancer; 2020 May; 20(1):434. PubMed ID: 32423468
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Screening and Identification of Differentially Expressed Genes Expressed among Left and Right Colon Adenocarcinoma.
    Han J; Zhang X; Yang Y; Feng L; Wang GY; Zhang N
    Biomed Res Int; 2020; 2020():8465068. PubMed ID: 32420374
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. LINC00342 regulates cell proliferation, apoptosis, migration and invasion in colon adenocarcinoma via miR-545-5p/mdm2 axis.
    Miao Z; Liu S; Xiao X; Li D
    Gene; 2020 Jun; 743():144604. PubMed ID: 32213297
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/mdm2 axis in colorectal cancer.
    Deng X; Li S; Kong F; Ruan H; Xu X; Zhang X; Wu Z; Zhang L; Xu Y; Yuan H; Peng H; Yang D; Guan M
    Theranostics; 2020; 10(1):265-280. PubMed ID: 31903119
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Genetic variants in p53 signaling pathway genes predict chemotherapy efficacy in colorectal cancer.
    Zhang K; Meng Y; Cao X; Xu Y; Du M; Wu Y; Liu L
    Cancer Med; 2019 Jul; 8(7):3428-3436. PubMed ID: 31090204
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. UBA2 promotes proliferation of colorectal cancer.
    He P; Sun X; Cheng HJ; Zou YB; Wang Q; Zhou CL; Liu WQ; Hao YM; Meng XW
    Mol Med Rep; 2018 Dec; 18(6):5552-5562. PubMed ID: 30387828
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Contribution of Murine Double Minute 2 Genotypes to colorectal cancer Risk in Taiwan.
    Yueh TC; Hung YW; Shih TC; Wu CN; Wang SC; Lai YL; Hsu SW; Wu MH; Fu CK; Wang YC; Ke TW; Chang WS; Tsai CW; Bau DT
    Cancer Genomics Proteomics; 2018; 15(5):405-411. PubMed ID: 30194081
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Cyclophilin B induces chemoresistance by degrading wild-type p53 via interaction with mdm2 in colorectal cancer.
    Choi TG; Nguyen MN; Kim J; Jo YH; Jang M; Nguyen NNY; Yun HR; Choe W; Kang I; Ha J; Tang DG; Kim SS
    J Pathol; 2018 Sep; 246(1):115-126. PubMed ID: 29876924
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment.
    Fitzgerald S; Espina V; Liotta L; Sheehan KM; O'Grady A; Cummins R; O'Kennedy R; Kay EW; Kijanka GS
    J Transl Med; 2018 Apr; 16(1):89. PubMed ID: 29631612
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth.
    An T; Gong Y; Li X; Kong L; Ma P; Gong L; Zhu H; Yu C; Liu J; Zhou H; Mao B; Li Y
    Biochem Pharmacol; 2017 May; 131():29-39. PubMed ID: 28216017
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/mdm2/CtBP and repression of macroH2A1.
    de Barrios O; Győrffy B; Fernández-Aceñero MJ; Sánchez-Tilló E; Sánchez-Moral L; Siles L; Esteve-Arenys A; Roué G; Casal JI; Darling DS; Castells A; Postigo A
    Gut; 2017 Apr; 66(4):666-682. PubMed ID: 27965283
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