Terms: = Colorectal cancer AND MED12, Q93074, TRAP230, TNRC11, OKS, KIAA0192, HOPA, FGS1, CAGH45, ARC240, 9968
14 results:
1. Genomic Characterization and Clinical Outcomes of Patients with Peritoneal Metastases from the AACR GENIE Biopharma Collaborative colorectal cancer Registry.
Sanz-Garcia E; Brown S; Lavery JA; Weiss J; Fuchs HE; Newcomb A; Postle A; Warner JL; LeNoue-Newton ML; Sweeney SM; Pillai S; Yu C; Nichols C; Mastrogiacomo B; Kundra R; Schultz N; Kehl KL; Riely GJ; Schrag D; Govindarajan A; Panageas KS; Bedard PL
Cancer Res Commun; 2024 Feb; 4(2):475-486. PubMed ID: 38329392
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2. The novel mechanism of med12-mediated drug resistance in a TGFBR2-independent manner.
Han Y; Dong Q; Liu T; Chen X; Yu C; Zhang Y
Biochem Biophys Res Commun; 2022 Jun; 610():1-7. PubMed ID: 35461070
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3. Colon cancer diagnosis and staging classification based on machine learning and bioinformatics analysis.
Su Y; Tian X; Gao R; Guo W; Chen C; Chen C; Jia D; Li H; Lv X
Comput Biol Med; 2022 Jun; 145():105409. PubMed ID: 35339846
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4. med12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase.
Sooraj D; Sun C; Doan A; Garama DJ; Dannappel MV; Zhu D; Chua HK; Mahara S; Wan Hassan WA; Tay YK; Guanizo A; Croagh D; Prodanovic Z; Gough DJ; Wan C; Firestein R
Mol Cell; 2022 Jan; 82(1):123-139.e7. PubMed ID: 34910943
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5. Prevalence of Forceps Polypectomy of Nondiminutive Polyps Is Substantial But Modifiable.
Fudman DI; Singal AG; Cooper MG; Lee M; Murphy CC
Clin Gastroenterol Hepatol; 2022 Jul; 20(7):1508-1515. PubMed ID: 34839039
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6. Whole exome sequencing of a gut-associated lymphoid tissue neoplasm points to precursor or early form of sporadic colon carcinoma.
Yaseen A; Ladenheim A; Olson KA; Libertini SJ; McPherson JD; Matsukuma K
Pathol Res Pract; 2021 Apr; 220():153406. PubMed ID: 33740545
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7. Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review).
Katoh M
Int J Mol Med; 2018 Aug; 42(2):713-725. PubMed ID: 29786110
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8. Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon cancer Cells.
Kuuluvainen E; Domènech-Moreno E; Niemelä EH; Mäkelä TP
Mol Cell Biol; 2018 Jun; 38(11):. PubMed ID: 29507187
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9. Oncogenic exon 2 mutations in Mediator subunit med12 disrupt allosteric activation of cyclin C-CDK8/19.
Park MJ; Shen H; Spaeth JM; Tolvanen JH; Failor C; Knudtson JF; McLaughlin J; Halder SK; Yang Q; Bulun SE; Al-Hendy A; Schenken RS; Aaltonen LA; Boyer TG
J Biol Chem; 2018 Mar; 293(13):4870-4882. PubMed ID: 29440396
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10.
Siraj AK; Masoodi T; Bu R; Pratheeshkumar P; Al-Sanea N; Ashari LH; Abduljabbar A; Alhomoud S; Al-Dayel F; Alkuraya FS; Al-Kuraya KS
Gut; 2018 Apr; 67(4):663-671. PubMed ID: 28183795
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11. Mutations in Exon 1 highlight the role of med12 in uterine leiomyomas.
Kämpjärvi K; Park MJ; Mehine M; Kim NH; Clark AD; Bützow R; Böhling T; Böhm J; Mecklin JP; Järvinen H; Tomlinson IP; van der Spuy ZM; Sjöberg J; Boyer TG; Vahteristo P
Hum Mutat; 2014 Sep; 35(9):1136-41. PubMed ID: 24980722
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12. Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients.
Guinney J; Ferté C; Dry J; McEwen R; Manceau G; Kao KJ; Chang KM; Bendtsen C; Hudson K; Huang E; Dougherty B; Ducreux M; Soria JC; Friend S; Derry J; Laurent-Puig P
Clin Cancer Res; 2014 Jan; 20(1):265-272. PubMed ID: 24170544
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13. Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells.
He L; Lu N; Dai Q; Zhao Y; Zhao L; Wang H; Li Z; You Q; Guo Q
Toxicology; 2013 Oct; 312():36-47. PubMed ID: 23907061
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14. Somatic med12 mutations in uterine leiomyosarcoma and colorectal cancer.
Kämpjärvi K; Mäkinen N; Kilpivaara O; Arola J; Heinonen HR; Böhm J; Abdel-Wahab O; Lehtonen HJ; Pelttari LM; Mehine M; Schrewe H; Nevanlinna H; Levine RL; Hokland P; Böhling T; Mecklin JP; Bützow R; Aaltonen LA; Vahteristo P
Br J Cancer; 2012 Nov; 107(10):1761-5. PubMed ID: 23132392
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