BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND MLH1, COCA2, 4292, ENSG00000076242, hMLH1, FCC2, HNPCC2, P40692, MGC5172, HNPCC
4516 results:

  • 1. [Expression of immune checkpoints PD-L1, CTLA4, LAG3 in the microenvironment of colon adenocarcinoma depending on MMR status].
    Naumov SS; Krakhmal NV; Tashireva LA; Vtorushin SV
    Arkh Patol; 2024; 86(2):6-13. PubMed ID: 38591901
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Methylation study of tumor suppressor genes in human aberrant crypt foci, colorectal carcinomas, and normal colon.
    Sarangi J; Das P; Ahmad A; Sulaiman M; Ghosh S; Gupta B; Panwar R; Pal S; Yadav R; Ahuja V; Sen S; Upadhyay AD; Dash NR; Sharma A; Gupta SD
    J Cancer Res Ther; 2024 Jan; 20(1):268-274. PubMed ID: 38554332
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Mismatch repair protein deficiency and its implications on distant metastasis in colorectal cancer: A comprehensive analysis.
    Fan C; Fang C; Wang W; Lv Z; Zhang X; Long F; Jiang Z; Li Y; Zhang H; Zhou ZG; Wang C; Sun XF
    Cancer Med; 2024 Apr; 13(7):e6994. PubMed ID: 38545852
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Epigenetic mlh1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques.
    Deycmar S; Johnson BJ; Ray K; Schaaf GW; Ryan DP; Cullin C; Dozier BL; Ferguson B; Bimber BN; Olson JD; Caudell DL; Whitlow CT; Solingapuram Sai KK; Romero EC; Villinger FJ; Burgos AG; Ainsworth HC; Miller LD; Hawkins GA; Chou JW; Gomes B; Hettich M; Ceppi M; Charo J; Cline JM
    J Transl Med; 2024 Mar; 22(1):292. PubMed ID: 38504345
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Clonal origin and genomic diversity in Lynch syndrome-associated endometrial cancer with multiple synchronous tumors: Identification of the pathogenicity of mlh1 p.L582H.
    Takahashi K; Yachida N; Tamura R; Adachi S; Kondo S; Abé T; Umezu H; Nyuzuki H; Okuda S; Nakaoka H; Yoshihara K
    Genes Chromosomes Cancer; 2024 Mar; 63(3):e23231. PubMed ID: 38459936
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Association between colorectal cancer, the frequency of Bacteroides fragilis, and the level of mismatch repair genes expression in the biopsy samples of Iranian patients.
    Nazarinejad N; Hajikhani B; Vaezi AA; Firoozeh F; Sameni F; Yaslianifard S; Goudarzi M; Dadashi M
    BMC Gastroenterol; 2024 Feb; 24(1):82. PubMed ID: 38395750
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Attenuated huntingtin gene CAG nucleotide repeat size in individuals with Lynch syndrome.
    Dalene Skarping K; Arning L; Petersén Å; Nguyen HP; Gebre-Medhin S
    Sci Rep; 2024 Feb; 14(1):4300. PubMed ID: 38383663
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Aberrant PRDM2 methylation as an early event in serrated lesions destined to evolve into microsatellite-instable colorectal cancers.
    van Toledo DE; Bleijenberg AG; Venema A; de Wit MJ; van Eeden S; Meijer GA; Carvalho B; Dekker E; Henneman P; IJspeert JE; van Noesel CJ
    J Pathol Clin Res; 2024 Mar; 10(2):e348. PubMed ID: 38380944
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Integrated analyses of the genetic and clinicopathological features of cholangiolocarcinoma: cholangiolocarcinoma may be characterized by mismatch-repair deficiency.
    Makino K; Ishii T; Takeda H; Saito Y; Fujiwara Y; Fujimoto M; Ito T; Wakama S; Kumagai K; Munekage F; Horie H; Tomofuji K; Oshima Y; Uebayashi EY; Kawai T; Ogiso S; Fukumitsu K; Takai A; Seno H; Hatano E
    J Pathol; 2024 May; 263(1):32-46. PubMed ID: 38362598
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Cold atmospheric plasma stabilizes mismatch repair for effective, uniform treatment of diverse colorectal cancer cell types.
    He Y; Lu F; Jiang C; Gong F; Wu Z; Ostrikov K
    Sci Rep; 2024 Feb; 14(1):3599. PubMed ID: 38351129
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. [Characteristics and clinical analysis of mlh1 c.463dupC gene mutation in a Lynch syndrome family].
    Zhou DY; Liu C; Huang J; Xu N; Ji X; Yang KX; Peng JB; Pan H; Xu WJ; Zhu Z
    Zhonghua Yi Xue Za Zhi; 2024 Feb; 104(7):547-551. PubMed ID: 38317368
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Rare germline mutation and MSH2-&MSH6 + expression in a double primary carcinoma of colorectal carcinoma and endometrial carcinoma: a case report.
    Zhang T; Huang X; Liu W; Ling X; Su Z; Huang M; Che S
    Diagn Pathol; 2024 Jan; 19(1):25. PubMed ID: 38297350
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Protective effect of alpha-lipoic acid and epalrestat on oxaliplatin-induced peripheral neuropathy in zebrafish.
    Lee DW; Park HC; Kim DH
    Muscle Nerve; 2024 Apr; 69(4):498-503. PubMed ID: 38294129
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Exploring the role of sporadic BRAF and KRAS mutations during colorectal cancer pathogenesis: A spotlight on the contribution of the endosome-lysosome system.
    Tang J; Lam GT; Brooks RD; Miles M; Useckaite Z; Johnson IR; Ung BS; Martini C; Karageorgos L; Hickey SM; Selemidis S; Hopkins AM; Rowland A; Vather R; O'Leary JJ; Brooks DA; Caruso MC; Logan JM
    Cancer Lett; 2024 Mar; 585():216639. PubMed ID: 38290660
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. High-throughput sequencing and in-silico analysis confirm pathogenicity of novel MSH3 variants in African American colorectal cancer.
    Rashid M; Rashid R; Gadewal N; Carethers JM; Koi M; Brim H; Ashktorab H
    Neoplasia; 2024 Mar; 49():100970. PubMed ID: 38281411
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Association of a novel frameshift variant and a known deleterious variant in MMR genes with Lynch syndrome in Chinese families.
    Li J; Ni H; Wang X; Cheng W; Li L; Cheng Y; Liu C; Li Y; Deng A
    World J Surg Oncol; 2024 Jan; 22(1):36. PubMed ID: 38280988
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Next-generation sequencing and immunohistochemistry approaches for microsatellite instability detection in endometrial cancer.
    Ali AS; Alalem LS
    Cell Mol Biol (Noisy-le-grand); 2023 Dec; 69(14):237-242. PubMed ID: 38279425
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Microsatellite Instability Is Insufficiently Used as a Biomarker for Lynch Syndrome Testing in Clinical Practice.
    Papadopoulou E; Rigas G; Fountzilas E; Boutis A; Giassas S; Mitsimponas N; Daliani D; Ziogas DC; Liontos M; Ramfidis V; Christophilakis C; Matthaios D; Floros T; Florou-Chatzigiannidou C; Agiannitopoulos K; Meintani A; Tsantikidi A; Katseli A; Potska K; Tsaousis G; Metaxa-Mariatou V; Nasioulas G
    JCO Precis Oncol; 2024 Jan; 8():e2300332. PubMed ID: 38271656
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Mismatch Repair Deficiency as a Predictive and Prognostic Biomarker in Endometrial cancer: A Review on Immunohistochemistry Staining Patterns and Clinical Implications.
    Addante F; d'Amati A; Santoro A; Angelico G; Inzani F; Arciuolo D; Travaglino A; Raffone A; D'Alessandris N; Scaglione G; Valente M; Tinnirello G; Sfregola S; Padial Urtueta B; Piermattei A; Cianfrini F; Mulè A; Bragantini E; Zannoni GF
    Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38256131
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Classification of mlh1 Missense VUS Using Protein Structure-Based Deep Learning-Ramachandran Plot-Molecular Dynamics Simulations Method.
    Tam B; Qin Z; Zhao B; Sinha S; Lei CL; Wang SM
    Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38255924
    [TBL] [Abstract] [Full Text] [Related]  


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