BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND MLH1, COCA2, 4292, ENSG00000076242, hMLH1, FCC2, HNPCC2, P40692, MGC5172, HNPCC AND Treatment
461 results:

  • 1. [Expression of immune checkpoints PD-L1, CTLA4, LAG3 in the microenvironment of colon adenocarcinoma depending on MMR status].
    Naumov SS; Krakhmal NV; Tashireva LA; Vtorushin SV
    Arkh Patol; 2024; 86(2):6-13. PubMed ID: 38591901
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Epigenetic mlh1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques.
    Deycmar S; Johnson BJ; Ray K; Schaaf GW; Ryan DP; Cullin C; Dozier BL; Ferguson B; Bimber BN; Olson JD; Caudell DL; Whitlow CT; Solingapuram Sai KK; Romero EC; Villinger FJ; Burgos AG; Ainsworth HC; Miller LD; Hawkins GA; Chou JW; Gomes B; Hettich M; Ceppi M; Charo J; Cline JM
    J Transl Med; 2024 Mar; 22(1):292. PubMed ID: 38504345
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Clonal origin and genomic diversity in Lynch syndrome-associated endometrial cancer with multiple synchronous tumors: Identification of the pathogenicity of mlh1 p.L582H.
    Takahashi K; Yachida N; Tamura R; Adachi S; Kondo S; Abé T; Umezu H; Nyuzuki H; Okuda S; Nakaoka H; Yoshihara K
    Genes Chromosomes Cancer; 2024 Mar; 63(3):e23231. PubMed ID: 38459936
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Cold atmospheric plasma stabilizes mismatch repair for effective, uniform treatment of diverse colorectal cancer cell types.
    He Y; Lu F; Jiang C; Gong F; Wu Z; Ostrikov K
    Sci Rep; 2024 Feb; 14(1):3599. PubMed ID: 38351129
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Protective effect of alpha-lipoic acid and epalrestat on oxaliplatin-induced peripheral neuropathy in zebrafish.
    Lee DW; Park HC; Kim DH
    Muscle Nerve; 2024 Apr; 69(4):498-503. PubMed ID: 38294129
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Association of a novel frameshift variant and a known deleterious variant in MMR genes with Lynch syndrome in Chinese families.
    Li J; Ni H; Wang X; Cheng W; Li L; Cheng Y; Liu C; Li Y; Deng A
    World J Surg Oncol; 2024 Jan; 22(1):36. PubMed ID: 38280988
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. [A Case of Stage Ⅳc dMMR Transverse Colon cancer with Complete Response to Combination Therapy with Immune Checkpoint Inhibitor in Stage ⅣB Lung Adenocarcinoma].
    Kageyama C; Yoshimatsu K; Tanaka H; Higashida M; Ito Y; Okada T; Endo S; Fujiwara Y; Ueno T
    Gan To Kagaku Ryoho; 2023 Oct; 50(10):1114-1116. PubMed ID: 38035848
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Metastasis of endometrial adenocarcinoma masquerading as a primary rectal cancer: A rare case report with literature review.
    Li M; Zheng W
    Medicine (Baltimore); 2023 Nov; 102(46):e36170. PubMed ID: 37986305
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Applicability of the FDA-approved Immunohistochemical Panel for Identification of MMRd Phenotype in Uterine Endometrioid Carcinoma.
    Adachi S; Kimata JI; Hanami K; Adachi K; Igarashi T; Liang SG; Ishida Y; Fujino T; Yamazaki K
    Appl Immunohistochem Mol Morphol; 2024 Jan; 32(1):24-31. PubMed ID: 37859432
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Phase II Trial of Nivolumab in Metastatic Rare cancer with dMMR or MSI-H and Relation with Immune Phenotypic Analysis (the ROCK Trial).
    Okuma HS; Watanabe K; Tsuchihashi K; Machida R; Sadachi R; Hirakawa A; Ariyama H; Kanai M; Kamikura M; Anjo K; Hiramitsu A; Sekine S; Okita N; Mano H; Nishikawa H; Nakamura K; Yonemori K
    Clin Cancer Res; 2023 Dec; 29(24):5079-5086. PubMed ID: 37819940
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Glioma arising in the setting of mismatch repair deficiency-rare or are we missing it?
    Goyal A; Rao S; Rishi KS; Ramaswamy V; Sadashiva N; Santosh V
    Childs Nerv Syst; 2024 Jan; 40(1):233-237. PubMed ID: 37733272
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Hormone Receptor-Positive Breast cancer Sensitive to Pembrolizumab: Evidence of the Pathogenicity of the mlh1 Variant 1835del3.
    Kaplan HG; Whiteaker JR; Nelson B; Ivey RG; Lorentzen TD; Voytovich U; Zhao L; Corwin DJ; Resta R; Paulovich AG
    J Natl Compr Canc Netw; 2023 Aug; 21(11):1110-1116. PubMed ID: 37643636
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Comprehensive profiling of DNA methylation in Korean patients with colorectal cancer.
    Shim H; Jang K; Bang YH; Chu HBK; Kang J; Lee JY; Cho S; Lee HS; Jeon J; Hwang T; Joe S; Lim J; Choi JH; Joo EH; Park K; Moon JH; Han KY; Hong Y; Lee WY; Kim HC; Yun SH; Cho YB; Park YA; Huh JW; Shin JK; Pyo DH; Hong H; Lee HO; Park WY; Yang JO; Kim YJ
    BMB Rep; 2024 Feb; 57(2):110-115. PubMed ID: 37605617
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Constitutional Mismatch Repair Deficiency Syndrome as a Cause of Numerous Malignancies in a Teenage Patient-A Case Report.
    Samborska M; Galli D; Achkar R; Thambyrajah S; Derwich K
    J Pediatr Hematol Oncol; 2023 Oct; 45(7):e917-e920. PubMed ID: 37526375
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Advances in vaccine development for cancer prevention and treatment in Lynch Syndrome.
    Bolivar AM; Duzagac F; Sinha KM; Vilar E
    Mol Aspects Med; 2023 Oct; 93():101204. PubMed ID: 37478804
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Uncommon variants detected via hereditary cancer panel and suggestions for genetic counseling.
    Özdemir Z; Çevik E; Öksüzoğlu ÖBÇ; Doğan M; Ateş Ö; Esin E; Bilgetekin İ; Demirci U; Köseoğlu Ç; Topal A; Karadurmuş N; Erdem HB; Bahsi T
    Mutat Res; 2023; 827():111831. PubMed ID: 37453313
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Polyps and colorectal cancer in Serrated Polyposis Syndrome: Contribution of the Classical Adenoma-Carcinoma and Serrated Neoplasia Pathways.
    van Toledo DEFWM; IJspeert JEG; Boersma H; Musler AR; Bleijenberg AGC; Dekker E; van Noesel CJM
    Clin Transl Gastroenterol; 2023 Aug; 14(8):e00611. PubMed ID: 37352472
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. A DNA damage response-like phenotype defines a third of colon cancers at onset.
    Mauro S; Bolognesi MM; Villa N; Capitoli G; Furia L; Mascadri F; Zucchini N; Totis M; Faretta M; Galimberti S; Bovo G; Cattoretti G
    FASEB J; 2023 Jul; 37(7):e23020. PubMed ID: 37342943
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Mismatch Repair Deficiency and Lynch Syndrome Among Adult Patients With Glioma.
    Benusiglio PR; Elder F; Touat M; Perrier A; Sanson M; Colas C; Guerrini-Rousseau L; Tran DT; Trabelsi N; Carpentier C; Marie Y; Adam C; Bernier M; Cazals-Hatem D; Mokhtari K; Tran S; Mathon B; Capelle L; Dhooge M; Idbaih A; Alentorn A; Houillier C; Dehais C; Hoang-Xuan K; Cuzzubbo S; Carpentier A; Duval A; Coulet F; Bielle F
    JCO Precis Oncol; 2023 May; 7():e2200525. PubMed ID: 37262394
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Lynch syndrome-associated chordoma with high tumor mutational burden and significant response to immune checkpoint inhibitors.
    Shinojima N; Ozono K; Yamamoto H; Abe S; Sasaki R; Tomita Y; Kai A; Mori R; Yamamoto T; Uekawa K; Matsui H; Nosaka K; Matsuzaki H; Komohara Y; Mikami Y; Mukasa A
    Brain Tumor Pathol; 2023 Jul; 40(3):185-190. PubMed ID: 37086325
    [TBL] [Abstract] [Full Text] [Related]  


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