Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND MTOR, FRAP2, FRAP1, 2475, ENSG00000198793, P42345, RAPT1, RAFT1, FRAP, FLJ44809 AND Treatment
559 results:

  • 1. PI3K/Akt/mtor Signaling Pathway as a Target for colorectal cancer treatment.
    Leiphrakpam PD; Are C
    Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542151
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  • 2. Inhibition of Multifunctional Protein p32/C1QBP Promotes Cytostatic Effects in Colon cancer Cells by Altering Mitogenic Signaling Pathways and Promoting Mitochondrial Damage.
    Egusquiza-Alvarez CA; Moreno-Londoño AP; Alvarado-Ortiz E; Ramos-Godínez MDP; Sarabia-Sánchez MA; Castañeda-Patlán MC; Robles-Flores M
    Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38473963
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  • 3. Broccoli extracellular vesicles enhance the therapeutic effects and restore the chemosensitivity of 5-fluorouracil on colon cancer.
    Cao Y; Hou L; Li M; Zhang J; Wang L; Liu C; Luo T; Yan L; Zheng L
    Food Chem Toxicol; 2024 Apr; 186():114563. PubMed ID: 38442787
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  • 4. Pyrvinium Pamoate Induces Cell Apoptosis and Autophagy in colorectal cancer.
    Zheng W; Chen K; Lv Y; Lao W; Zhu H
    Anticancer Res; 2024 Mar; 44(3):1193-1199. PubMed ID: 38423653
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  • 5. Selective Synergy of Rapamycin Combined With Methioninase on cancer Cells Compared to Normal Cells.
    Ardjmand D; Kubota Y; Sato M; Han Q; Mizuta K; Morinaga S; Hoffman RM
    Anticancer Res; 2024 Mar; 44(3):929-933. PubMed ID: 38423628
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  • 6. Phase I study of sapanisertib (CB-228/TAK-228/MLN0128) in combination with ziv-aflibercept in patients with advanced solid tumors.
    Coleman N; Stephen B; Fu S; Karp D; Subbiah V; Ahnert JR; Piha-Paul SA; Wright J; Fessahaye SN; Ouyang F; Yilmaz B; Meric-Bernstam F; Naing A
    Cancer Med; 2024 Feb; 13(3):e6877. PubMed ID: 38400671
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  • 7. A free fatty acid receptor agonist inducing autophagy in HT-29 cells by downregulating the AKT/mtor signaling pathway.
    Hoveizi E; Rafienia B; Shahriari A
    J Cancer Res Ther; 2023 Oct; 19(7):1931-1938. PubMed ID: 38376299
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  • 8. Everolimus exerts anticancer effects through inhibiting the interaction of matrix metalloproteinase-7 with syndecan-2 in colon cancer cells.
    Lee S; Jang B; Hwang J; Lee Y; Cho S; Yang H; Yun JH; Shin DH; Lee W; Oh ES
    Am J Physiol Cell Physiol; 2024 Apr; 326(4):C1067-C1079. PubMed ID: 38314724
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  • 9. Integrating cfDNA liquid biopsy and organoid-based drug screening reveals PI3K signaling as a promising therapeutic target in colorectal cancer.
    Yang H; Xiao X; Zeng L; Zeng H; Zheng Y; Wang J; Li G; Dai W; He Y; Wang S; Peng J; Chen W
    J Transl Med; 2024 Feb; 22(1):132. PubMed ID: 38310289
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  • 10. In vitro and in vivo anti-colorectal cancer effect of the newly synthesized sericin/propolis/fluorouracil nanoplatform through modulation of PI3K/AKT/mtor pathway.
    Diab SE; Tayea NA; Elwakil BH; Elshewemi SS; Gad AAEM; Abdulmalek SA; Ghareeb DA; Olama ZA
    Sci Rep; 2024 Jan; 14(1):2433. PubMed ID: 38286826
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  • 11. Deletion of IL-27p28 induces CD8 T cell immunity against colorectal tumorigenesis.
    Li P; Pu S; Yi J; Li X; Wu Q; Yang C; Kang M; Peng F; Zhou Z
    Int Immunopharmacol; 2024 Feb; 128():111464. PubMed ID: 38224627
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  • 12. Novel sulfonyl-substituted tetrandrine derivatives for colon cancer treatment by inducing mitochondrial apoptosis and inhibiting PI3K/AKT/mtor pathway.
    Ling J; Li X; Wang M; Zhang C; Liu Y; Zhang X; Liu C; Ren Q; Zeng Y; Wang C; Chen Y; Sun C; Chen H; Zuo Y; Cao X; Deng Y; Ren B; Li D; Lu J
    Bioorg Chem; 2024 Feb; 143():107069. PubMed ID: 38160477
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  • 13. Ursolic acid inhibits the metastasis of colon cancer by downregulating ARL4C expression.
    Zhang M; Xiang F; Sun Y; Liu R; Li Q; Gu Q; Kang X; Wu R
    Oncol Rep; 2024 Feb; 51(2):. PubMed ID: 38131251
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  • 14. Phase I Study of mtorC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mtor/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
    Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
    Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
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  • 15. MiR-26a-5p exerts its influence by targeting EP300, a molecule known for its role in activating the PI3K/AKT/mtor signaling pathway in CD8+tumor-infiltrating lymphocytes of colorectal cancer.
    Wang C; Lin H; Zhao W; Liang Y; Chen Y; Wang C
    Cell Mol Biol (Noisy-le-grand); 2023 Nov; 69(12):232-241. PubMed ID: 38063089
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. TP53/mtorC1-mediated bidirectional regulation of PD-L1 modulates immune evasion in hepatocellular carcinoma.
    Yu J; Ling S; Hong J; Zhang L; Zhou W; Yin L; Xu S; Que Q; Wu Y; Zhan Q; Bao J; Xu N; Liu Y; Chen K; Wei X; Liu Z; Feng T; Zhou L; Xie H; Wang S; Liu J; Zheng S; Xu X
    J Immunother Cancer; 2023 Nov; 11(11):. PubMed ID: 38030304
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Ginseng-derived nanoparticles reprogram macrophages to regulate arginase-1 release for ameliorating T cell exhaustion in tumor microenvironment.
    Lv Y; Li M; Weng L; Huang H; Mao Y; Yang DA; Wei Q; Zhao M; Wei Q; Rui K; Han X; Fan W; Cai X; Cao P; Cao M
    J Exp Clin Cancer Res; 2023 Nov; 42(1):322. PubMed ID: 38012650
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  • 18. Bio Informatics Analysis of the Relationship Between Mammalian Target of Rapamycin and colorectal cancer.
    Han L; Lin L; Chen J; Yan B
    Stud Health Technol Inform; 2023 Nov; 308():322-328. PubMed ID: 38007756
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  • 19. Pathogenic alterations in PIK3CA and KMT2C are frequent and independent prognostic factors in anal squamous cell carcinoma treated with salvage abdominoperineal resection.
    Hamza A; Masliah-Planchon J; Neuzillet C; Lefèvre JH; Svrcek M; Vacher S; Bourneix C; Delaye M; Goéré D; Dartigues P; Samalin E; Hilmi M; Lazartigues J; Girard E; Emile JF; Rigault E; Dangles-Marie V; Rioux-Leclercq N; de la Fouchardière C; Tougeron D; Casadei-Gardini A; Mariani P; Peschaud F; Cacheux W; Lièvre A; Bièche I
    Int J Cancer; 2024 Feb; 154(3):504-515. PubMed ID: 37908048
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Comprehensive exploration of Biochanin A as an oncotherapeutics potential in the treatment of multivarious cancers with molecular insights.
    Sohel M
    Phytother Res; 2024 Feb; 38(2):489-506. PubMed ID: 37905329
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