Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND MYCN, N-myc, 4613, ENSG00000134323, NMYC, MODED, ODED
94 results:

  • 1. CKLF instigates a "cold" microenvironment to promote mycn-mediated tumor aggressiveness.
    Qin X; Lam A; Zhang X; Sengupta S; Iorgulescu JB; Ni H; Das S; Rager M; Zhou Z; Zuo T; Meara GK; Floru AE; Kemet C; Veerapaneni D; Kashy D; Lin L; Lloyd K; Kwok L; Smith KS; Nagaraju RT; Meijers R; Ceol C; Liu CT; Alexandrescu S; Wu CJ; Keskin DB; George RE; Feng H
    Sci Adv; 2024 Mar; 10(11):eadh9547. PubMed ID: 38489372
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. First-line Palliative Chemotherapy for colorectal cancer: a Population-based Analysis of Delivery and Outcomes in a Single-payer Health System.
    Wilson BE; Booth CM; Patel S; Berry S; Kong W; Merchant SJ
    Clin Oncol (R Coll Radiol); 2024 Apr; 36(4):211-220. PubMed ID: 38199907
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. RPF2 mediates the CARM1‑mycn axis to promote chemotherapy resistance in colorectal cancer cells.
    Lu M; Hu X; Cheng C; Zhang Y; Huang L; Kong X; Li Z; Zhang Q; Zhang Y
    Oncol Rep; 2024 Jan; 51(1):. PubMed ID: 37997821
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Antitumor Activity of Piceamycin by Upregulation of n-myc Downstream-Regulated Gene 1 in Human colorectal cancer Cells.
    Kyaw KZ; Byun WS; Shin YH; Huynh TH; Lee JY; Bae ES; Park HJ; Oh DC; Lee SK
    J Nat Prod; 2022 Dec; 85(12):2817-2827. PubMed ID: 36458922
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Effect of radical lymphadenectomy in colorectal cancer with para-aortic lymph node metastasis: a systematic review and meta-analysis.
    Zhao P; Yang X; Yan Y; Yang J; Li S; Du X
    BMC Surg; 2022 May; 22(1):181. PubMed ID: 35568938
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Claudin-2 promotes colorectal cancer growth and metastasis by suppressing NDRG1 transcription.
    Wei M; Zhang Y; Yang X; Ma P; Li Y; Wu Y; Chen X; Deng X; Yang T; Mao X; Qiu L; Meng W; Zhang B; Wang Z; Han J
    Clin Transl Med; 2021 Dec; 11(12):e667. PubMed ID: 34965023
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer.
    Yang G; Huang L; Jia H; Aikemu B; Zhang S; Shao Y; Hong H; Yesseyeva G; Wang C; Li S; Sun J; Zheng M; Ma J
    Oncogene; 2021 Oct; 40(41):5993-6006. PubMed ID: 34385595
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. NDRG1 regulates Filopodia-induced colorectal cancer invasiveness via modulating CDC42 activity.
    Aikemu B; Shao Y; Yang G; Ma J; Zhang S; Yang X; Hong H; Yesseyeva G; Huang L; Jia H; Wang C; Zang L; Sun J; Zheng M
    Int J Biol Sci; 2021; 17(7):1716-1730. PubMed ID: 33994856
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.
    Vaes N; Schonkeren SL; Rademakers G; Holland AM; Koch A; Gijbels MJ; Keulers TG; de Wit M; Moonen L; Van der Meer JRM; van den Boezem E; Wolfs TGAM; Threadgill DW; Demmers J; Fijneman RJA; Jimenez CR; Vanden Berghe P; Smits KM; Rouschop KMA; Boesmans W; Hofstra RMW; Melotte V
    EMBO Rep; 2021 Jun; 22(6):e51913. PubMed ID: 33890711
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. LncRNA RAD51-AS1/miR-29b/c-3p/NDRG2 crosstalk repressed proliferation, invasion and glycolysis of colorectal cancer.
    Li C; Wang P; Du J; Chen J; Liu W; Ye K
    IUBMB Life; 2021 Jan; 73(1):286-298. PubMed ID: 33314669
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Steroid receptor-associated and regulated protein is a biomarker in predicting the clinical outcome and treatment response in malignancies.
    Naderi A
    Cancer Rep (Hoboken); 2020 Oct; 3(5):e1267. PubMed ID: 32706923
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. DERL3 suppresses colorectal cancer metastasis through negatively regulating mycn level.
    Yu F; Mou B; Sheng J; Liu J; Qin X; Yu J
    Minerva Med; 2023 Jun; 114(3):316-322. PubMed ID: 32538588
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Thymidylate synthase inhibitor raltitrexed can induce high levels of DNA damage in mycn-amplified neuroblastoma cells.
    Yamashita K; Kiyonari S; Tsubota S; Kishida S; Sakai R; Kadomatsu K
    Cancer Sci; 2020 Jul; 111(7):2431-2439. PubMed ID: 32415892
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. n-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21.
    Zhang S; Yu C; Yang X; Hong H; Lu J; Hu W; Hao X; Li S; Aikemu B; Yang G; He Z; Zhang L; Xue P; Cai Z; Ma J; Zang L; Feng B; Yuan F; Sun J; Zheng M
    J Exp Clin Cancer Res; 2019 Dec; 38(1):490. PubMed ID: 31831018
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. NMI promotes cell proliferation through TGFβ/Smad pathway by upregulating STAT1 in colorectal cancer.
    Ji D; Feng Y; Peng W; Li J; Gu Q; Zhang Z; Qian W; Wang Q; Zhang Y; Sun Y
    J Cell Physiol; 2020 Jan; 235(1):429-441. PubMed ID: 31230364
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Emerging Roles of C-Myc in cancer Stem Cell-Related Signaling and Resistance to cancer Chemotherapy: A Potential Therapeutic Target Against colorectal cancer.
    Elbadawy M; Usui T; Yamawaki H; Sasaki K
    Int J Mol Sci; 2019 May; 20(9):. PubMed ID: 31083525
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling.
    Iniguez AB; Alexe G; Wang EJ; Roti G; Patel S; Chen L; Kitara S; Conway A; Robichaud AL; Stolte B; Bandopadhayay P; Goodale A; Pantel S; Lee Y; Cheff DM; Hall MD; Guha R; Davis MI; Menard M; Nasholm N; Weiss WA; Qi J; Beroukhim R; Piccioni F; Johannessen C; Stegmaier K
    Cancer Cell; 2018 Dec; 34(6):922-938.e7. PubMed ID: 30537514
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The prognostic value of decreased NDRG1 expression in patients with digestive system cancers: A meta-analysis.
    Chen K; Liu XH; Wang FR; Liu HP; Huang ZP; Chen X
    Medicine (Baltimore); 2018 Oct; 97(41):e12455. PubMed ID: 30313035
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Identification of high-risk human papillomavirus and Rb/E2F pathway genomic alterations in mutually exclusive subsets of colorectal neuroendocrine carcinoma.
    Shamir ER; Devine WP; Pekmezci M; Umetsu SE; Krings G; Federman S; Cho SJ; Saunders TA; Jen KY; Bergsland E; Jones K; Kim GE; Kakar S; Chiu CY; Joseph NM
    Mod Pathol; 2019 Feb; 32(2):290-305. PubMed ID: 30237525
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. A combined literature and in silico analysis enlightens the role of the NDRG family in the gut.
    Vaes N; Schonkeren SL; Brosens E; Koch A; McCann CJ; Thapar N; Hofstra RMW; van Engeland M; Melotte V
    Biochim Biophys Acta Gen Subj; 2018 Oct; 1862(10):2140-2151. PubMed ID: 30033230
    [TBL] [Abstract] [Full Text] [Related]  


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