Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND MYCN, N-myc, 4613, ENSG00000134323, NMYC, MODED, ODED AND Treatment
23 results:

  • 1. CKLF instigates a "cold" microenvironment to promote mycn-mediated tumor aggressiveness.
    Qin X; Lam A; Zhang X; Sengupta S; Iorgulescu JB; Ni H; Das S; Rager M; Zhou Z; Zuo T; Meara GK; Floru AE; Kemet C; Veerapaneni D; Kashy D; Lin L; Lloyd K; Kwok L; Smith KS; Nagaraju RT; Meijers R; Ceol C; Liu CT; Alexandrescu S; Wu CJ; Keskin DB; George RE; Feng H
    Sci Adv; 2024 Mar; 10(11):eadh9547. PubMed ID: 38489372
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. First-line Palliative Chemotherapy for colorectal cancer: a Population-based Analysis of Delivery and Outcomes in a Single-payer Health System.
    Wilson BE; Booth CM; Patel S; Berry S; Kong W; Merchant SJ
    Clin Oncol (R Coll Radiol); 2024 Apr; 36(4):211-220. PubMed ID: 38199907
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Antitumor Activity of Piceamycin by Upregulation of n-myc Downstream-Regulated Gene 1 in Human colorectal cancer Cells.
    Kyaw KZ; Byun WS; Shin YH; Huynh TH; Lee JY; Bae ES; Park HJ; Oh DC; Lee SK
    J Nat Prod; 2022 Dec; 85(12):2817-2827. PubMed ID: 36458922
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Effect of radical lymphadenectomy in colorectal cancer with para-aortic lymph node metastasis: a systematic review and meta-analysis.
    Zhao P; Yang X; Yan Y; Yang J; Li S; Du X
    BMC Surg; 2022 May; 22(1):181. PubMed ID: 35568938
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Claudin-2 promotes colorectal cancer growth and metastasis by suppressing NDRG1 transcription.
    Wei M; Zhang Y; Yang X; Ma P; Li Y; Wu Y; Chen X; Deng X; Yang T; Mao X; Qiu L; Meng W; Zhang B; Wang Z; Han J
    Clin Transl Med; 2021 Dec; 11(12):e667. PubMed ID: 34965023
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer.
    Yang G; Huang L; Jia H; Aikemu B; Zhang S; Shao Y; Hong H; Yesseyeva G; Wang C; Li S; Sun J; Zheng M; Ma J
    Oncogene; 2021 Oct; 40(41):5993-6006. PubMed ID: 34385595
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. LncRNA RAD51-AS1/miR-29b/c-3p/NDRG2 crosstalk repressed proliferation, invasion and glycolysis of colorectal cancer.
    Li C; Wang P; Du J; Chen J; Liu W; Ye K
    IUBMB Life; 2021 Jan; 73(1):286-298. PubMed ID: 33314669
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Steroid receptor-associated and regulated protein is a biomarker in predicting the clinical outcome and treatment response in malignancies.
    Naderi A
    Cancer Rep (Hoboken); 2020 Oct; 3(5):e1267. PubMed ID: 32706923
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Thymidylate synthase inhibitor raltitrexed can induce high levels of DNA damage in mycn-amplified neuroblastoma cells.
    Yamashita K; Kiyonari S; Tsubota S; Kishida S; Sakai R; Kadomatsu K
    Cancer Sci; 2020 Jul; 111(7):2431-2439. PubMed ID: 32415892
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Identification of high-risk human papillomavirus and Rb/E2F pathway genomic alterations in mutually exclusive subsets of colorectal neuroendocrine carcinoma.
    Shamir ER; Devine WP; Pekmezci M; Umetsu SE; Krings G; Federman S; Cho SJ; Saunders TA; Jen KY; Bergsland E; Jones K; Kim GE; Kakar S; Chiu CY; Joseph NM
    Mod Pathol; 2019 Feb; 32(2):290-305. PubMed ID: 30237525
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. n-myc downstream-regulated gene 1 promotes oxaliplatin-triggered apoptosis in colorectal cancer cells via enhancing the ubiquitination of Bcl-2.
    Yang X; Zhu F; Yu C; Lu J; Zhang L; Lv Y; Sun J; Zheng M
    Oncotarget; 2017 Jul; 8(29):47709-47724. PubMed ID: 28537875
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells.
    Mi L; Zhu F; Yang X; Lu J; Zheng Y; Zhao Q; Wen X; Lu A; Wang M; Zheng M; Ji J; Sun J
    Oncogene; 2017 Jul; 36(30):4323-4335. PubMed ID: 28346422
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. NDRG2, suppressed expression associates with poor prognosis in pancreatic cancer, is hypermethylated in the second promoter in human gastrointestinal cancers.
    Yamamura A; Miura K; Karasawa H; Motoi F; Mizuguchi Y; Saiki Y; Fukushige S; Sunamura M; Shibata C; Unno M; Horii A
    Biochem Biophys Res Commun; 2017 Feb; 484(1):138-143. PubMed ID: 28093228
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Wnt signalling is a bi-directional vulnerability of cancer cells.
    Duffy DJ; Krstic A; Schwarzl T; Halasz M; Iljin K; Fey D; Haley B; Whilde J; Haapa-Paananen S; Fey V; Fischer M; Westermann F; Henrich KO; Bannert S; Higgins DG; Kolch W
    Oncotarget; 2016 Sep; 7(37):60310-60331. PubMed ID: 27531891
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Bioinformatic analysis of potential candidates for therapy of inflammatory bowel disease.
    Li XL; Zhou CY; Sun Y; Su ZY; Wang X; N Jia E; Zhang Q; Jiang XF; Qi WQ; Xu Y
    Eur Rev Med Pharmacol Sci; 2015 Nov; 19(22):4275-84. PubMed ID: 26636514
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The Metastasis Suppressor, n-myc Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
    Kovacevic Z; Menezes SV; Sahni S; Kalinowski DS; Bae DH; Lane DJ; Richardson DR
    J Biol Chem; 2016 Jan; 291(3):1029-52. PubMed ID: 26534963
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.
    Vieira GC; Chockalingam S; Melegh Z; Greenhough A; Malik S; Szemes M; Park JH; Kaidi A; Zhou L; Catchpoole D; Morgan R; Bates DO; Gabb PD; Malik K
    Oncotarget; 2015 Nov; 6(37):40053-67. PubMed ID: 26517508
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. NDRG2 positively regulates E-cadherin expression and prolongs overall survival in colon cancer patients.
    Kim YJ; Kang HB; Yim HS; Kim JH; Kim JW
    Oncol Rep; 2013 Oct; 30(4):1890-8. PubMed ID: 23900729
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model.
    Deuschle U; Schüler J; Schulz A; Schlüter T; Kinzel O; Abel U; Kremoser C
    PLoS One; 2012; 7(10):e43044. PubMed ID: 23056173
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Clinicopathological risk factors of Stage II colon cancer: results of a prospective study.
    Santos C; López-Doriga A; Navarro M; Mateo J; Biondo S; Martínez Villacampa M; Soler G; Sanjuan X; Paules MJ; Laquente B; Guinó E; Kreisler E; Frago R; Germà JR; Moreno V; Salazar R
    Colorectal Dis; 2013 Apr; 15(4):414-22. PubMed ID: 22974322
    [TBL] [Abstract] [Full Text] [Related]  


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