Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND NFE2L2, ENSG00000116044, 4780, Q16236, NRF2 AND Treatment
129 results:

  • 1. Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells.
    Salerno L; Notaro A; Consoli V; Affranchi F; Pittalà V; Sorrenti V; Vanella L; Giuliano M; Intagliata S
    J Enzyme Inhib Med Chem; 2024 Dec; 39(1):2337191. PubMed ID: 38634597
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Esculin induces endoplasmic reticulum stress and drives apoptosis and ferroptosis in colorectal cancer via PERK regulating eIF2α/CHOP and nrf2/HO-1 cascades.
    Ji X; Chen Z; Lin W; Wu Q; Wu Y; Hong Y; Tong H; Wang C; Zhang Y
    J Ethnopharmacol; 2024 Jun; 328():118139. PubMed ID: 38561058
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  • 3. Chemopreventive Effects of Polysaccharides and Flavonoids from Okra Flowers in Azomethane/Dextran Sulfate Sodium-Induced Murine Colitis-Associated cancer.
    Deng Y; Huang X; Chen X; Wang M; Tian L; Zhou H; Yang W; He F; Yin W
    Nutrients; 2023 Nov; 15(22):. PubMed ID: 38004214
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  • 4. FOXA2 Suppression by TRIM36 Exerts Anti-Tumor Role in colorectal cancer Via Inducing nrf2/GPX4-Regulated Ferroptosis.
    Liu X; Yan C; Chang C; Meng F; Shen W; Wang S; Zhang Y
    Adv Sci (Weinh); 2023 Dec; 10(35):e2304521. PubMed ID: 37875418
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  • 5. Ochratoxin A promotes chronic enteritis and early colorectal cancer progression by targeting Rinck signaling.
    Liu X; Yan C; Chang C; Meng F; Shen W; Wang S; Zhang Y
    Phytomedicine; 2024 Jan; 122():155095. PubMed ID: 37844381
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  • 6. Allyl-isothiocyanate against colorectal cancer via the mutual dependent regulation of p21 and nrf2.
    Ren X; Zhang G; Ling X; Zhang L; Tian Y; Zhu G; Wang P; Leavenworth JW; Luo L; Li F
    Eur J Pharmacol; 2023 Oct; 957():176016. PubMed ID: 37634842
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  • 7. Fisetin induces apoptosis in colorectal cancer cells by suppressing autophagy and down-regulating nuclear factor erythroid 2-related factor 2 (nrf2).
    Pandey A; Trigun SK
    J Cell Biochem; 2023 Sep; 124(9):1289-1308. PubMed ID: 37450699
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  • 8. ACTL6A protects gastric cancer cells against ferroptosis through induction of glutathione synthesis.
    Yang Z; Zou S; Zhang Y; Zhang J; Zhang P; Xiao L; Xie Y; Meng M; Feng J; Kang L; Lee MH; Fang L
    Nat Commun; 2023 Jul; 14(1):4193. PubMed ID: 37443154
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  • 9. Nuclear Factor Erythroid 2-Related Factor 2/Kelch-Like ECH-Associated Protein 1 as a Predictor of Prognosis and Radiotherapy Resistance in Patients With Locally Advanced Rectal cancer: A Prospective Analysis.
    Park JM; Kim S; Bae SU; Byun SJ; Seo I; Lee HW
    J Korean Med Sci; 2023 Jul; 38(26):e200. PubMed ID: 37401495
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  • 10. The role of nrf2 in the pathogenesis and treatment of ulcerative colitis.
    Peng S; Shen L; Yu X; Zhang L; Xu K; Xia Y; Zha L; Wu J; Luo H
    Front Immunol; 2023; 14():1200111. PubMed ID: 37359553
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  • 11. Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancer.
    Wu W; Zhao Y; Qin B; Jiang X; Wang C; Hu R; Ma R; Lee MH; Liu H; Li K; Yuan P
    EBioMedicine; 2023 Jul; 93():104650. PubMed ID: 37343364
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  • 12. Blastocystis sp. reduces the efficacy of 5-fluorouracil as a colorectal cancer chemotherapeutic treatment.
    Kumarasamy V; Kuppusamy UR; Jayalakshmi P; Govind SK
    Exp Parasitol; 2023 Aug; 251():108564. PubMed ID: 37308003
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Natural products targeting nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease.
    Li B; Wang Y; Jiang X; Du H; Shi Y; Xiu M; Liu Y; He J
    Biomed Pharmacother; 2023 Aug; 164():114950. PubMed ID: 37263167
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  • 14. Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
    Wang C; Dai S; Zhao X; Zhang Y; Gong L; Fu K; Ma C; Peng C; Li Y
    Biomed Pharmacother; 2023 Jul; 163():114882. PubMed ID: 37196541
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  • 15. Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
    Wang G; Qin S; Chen L; Geng H; Zheng Y; Xia C; Yao J; Deng L
    Cell Death Dis; 2023 Apr; 14(4):292. PubMed ID: 37185889
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  • 16. Genetic polymorphisms in genes regulating cell death and prognosis of patients with rectal cancer receiving postoperative chemoradiotherapy.
    Chen H; Yin L; Yang J; Ren N; Chen J; Lu Q; Huang Y; Feng Y; Wang W; Wang S; Liu Y; Song Y; Li Y; Jin J; Tan W; Lin D
    Cancer Biol Med; 2023 May; 20(4):297-316. PubMed ID: 37144561
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Protective Effects of Piceatannol on DNA Damage in Benzo[
    Chang CH; Lien YT; Lin WS; Nagabhushanam K; Ho CT; Pan MH
    J Agric Food Chem; 2023 May; 71(19):7370-7381. PubMed ID: 37142545
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  • 18. Electrophilic reactive aldehydes as a therapeutic target in colorectal cancer prevention and treatment.
    Gobert AP; Asim M; Smith TM; Williams KJ; Barry DP; Allaman MM; McNamara KM; Hawkins CV; Delgado AG; Zhao S; Piazuelo MB; Washington MK; Coburn LA; Rathmacher JA; Wilson KT
    Oncogene; 2023 May; 42(20):1685-1691. PubMed ID: 37037901
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  • 19. Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.
    Wu S; Tian C; Tu Z; Guo J; Xu F; Qin W; Chang H; Wang Z; Hu T; Sun X; Ning H; Li Y; Gou W; Hou W
    J Ethnopharmacol; 2023 Jul; 311():116428. PubMed ID: 36997130
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Ibrutinib facilitates the sensitivity of colorectal cancer cells to ferroptosis through BTK/nrf2 pathway.
    Zhu JF; Liu Y; Li WT; Li MH; Zhen CH; Sun PW; Chen JX; Wu WH; Zeng W
    Cell Death Dis; 2023 Feb; 14(2):151. PubMed ID: 36823108
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