Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND NT5C2, ENSG00000076685, 22978, P49902, PNT5, NT5B, GMP, cN-II
78 results:

  • 1. Wnt/β-catenin signalling activates IMPDH2-mediated purine metabolism to facilitate oxaliplatin resistance by inhibiting caspase-dependent apoptosis in colorectal cancer.
    Huang Y; Chan S; Chen S; Liu X; Li M; Zheng L; Dong Z; Yang Z; Liu Z; Zhou D; Zhang X; Zhang B
    J Transl Med; 2024 Feb; 22(1):133. PubMed ID: 38310229
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation.
    Chen B; Hong Y; Zhai X; Deng Y; Hu H; Tian S; Zhang Y; Ren X; Zhao J; Jiang C
    Cell Death Dis; 2023 Dec; 14(12):809. PubMed ID: 38065948
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. [The Potential of a Novel Therapeutic Strategy for colorectal cancer Targeting the cGAS-STING Pathway].
    Nakajima S; Kaneta A; Kono K
    Gan To Kagaku Ryoho; 2023 Sep; 50(9):950-954. PubMed ID: 37800285
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Inhibition of tumor intrinsic BANF1 activates antitumor immune responses via cGAS-STING and enhances the efficacy of PD-1 blockade.
    Wang M; Huang Y; Chen M; Wang W; Wu F; Zhong T; Chen X; Wang F; Li Y; Yu J; Wu M; Chen D
    J Immunother Cancer; 2023 Aug; 11(8):. PubMed ID: 37620043
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Integration of bulk RNA sequencing data and single-cell RNA sequencing analysis on the heterogeneity in patients with colorectal cancer.
    Zhang J; Wu Y; Shen Z
    Funct Integr Genomics; 2023 Jun; 23(3):209. PubMed ID: 37355491
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Activatable Mn
    Liang Q; Chen J; Hou S; Li D; Zhu Y; Li R; Chen L; Li J; Fu W; Lei S; Zhang B; Zheng X; Zhang T; Duan H; He W; Ren J
    Biomaterials; 2023 Sep; 300():122206. PubMed ID: 37348325
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity.
    Fang L; Hao Y; Yu H; Gu X; Peng Q; Zhuo H; Li Y; Liu Z; Wang J; Chen Y; Zhang J; Tian H; Gao Y; Gao R; Teng H; Shan Z; Zhu J; Li Z; Liu Y; Zhang Y; Yu F; Lin Z; Hao Y; Ge X; Yuan J; Hu HG; Ma Y; Qin HL; Wang P
    Cancer Cell; 2023 Jun; 41(6):1118-1133.e12. PubMed ID: 37267951
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Enhancing anti-tumor immunity through liposomal oxaliplatin and localized immunotherapy via STING activation.
    Gu Z; Hao Y; Schomann T; Ossendorp F; Ten Dijke P; Cruz LJ
    J Control Release; 2023 May; 357():531-544. PubMed ID: 37030544
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. An optimized IgG-based B7-H3xCD3 bispecific antibody for treatment of gastrointestinal cancers.
    Zekri L; Lutz M; Prakash N; Manz T; Klimovich B; Mueller S; Hoerner S; Hagelstein I; Engel M; Chashchina A; Pfluegler M; Heitmann JS; Jung G; Salih HR
    Mol Ther; 2023 Apr; 31(4):1033-1045. PubMed ID: 36793213
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Generation of colon cancer-derived tumor-infiltrating T cells (TILs) for adoptive cell therapy.
    Albrecht HC; Gustavus D; Schwanemann J; Dammermann W; Lippek F; Weylandt KH; Hoffmeister H; Gretschel S
    Cytotherapy; 2023 May; 25(5):537-547. PubMed ID: 36775787
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. [Expression of the cGAS-STING Pathway in dMMR/MSI-H in colorectal cancer].
    Kaneta A; Nakajima S; Mimura K; Kono K
    Gan To Kagaku Ryoho; 2022 Oct; 49(10):1130-1132. PubMed ID: 36281609
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. PARPi treatment enhances radiotherapy-induced ferroptosis and antitumor immune responses via the cGAS signaling pathway in colorectal cancer.
    Shen D; Luo J; Chen L; Ma W; Mao X; Zhang Y; Zheng J; Wang Y; Wan J; Wang S; Ouyang J; Yi H; Liu D; Huang W; Zhang W; Liu Z; McLeod HL; He Y
    Cancer Lett; 2022 Dec; 550():215919. PubMed ID: 36116741
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Genetic variants involved in the cGAS-STING pathway predict outcome in patients with metastatic colorectal cancer: Data from FIRE-3 and TRIBE trials.
    Wang J; Xiao Y; Loupakis F; Stintzing S; Yang Y; Arai H; Battaglin F; Kawanishi N; Jayachandran P; Soni S; Zhang W; Mancao C; Cremolini C; Liu T; Heinemann V; Falcone A; Shen L; Millstein J; Lenz HJ
    Eur J Cancer; 2022 Sep; 172():22-30. PubMed ID: 35749909
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorectal cancer.
    Kaneta A; Nakajima S; Okayama H; Matsumoto T; Saito K; Kikuchi T; Endo E; Ito M; Mimura K; Kanke Y; Saito M; Saze Z; Fujita S; Sakamoto W; Onozawa H; Momma T; Ohki S; Kono K
    Cancer Immunol Immunother; 2022 Nov; 71(11):2765-2776. PubMed ID: 35429245
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. cGAS-STING signaling pathway in gastrointestinal inflammatory disease and cancers.
    Ke X; Hu T; Jiang M
    FASEB J; 2022 Jan; 36(1):e22029. PubMed ID: 34907606
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Phase I double-blind, placebo-controlled trial of dolcanatide (SP-333) 27 mg to explore colorectal bioactivity in healthy volunteers.
    Weinberg DS; Foster NR; Della'Zanna G; McMurray RP; Kraft WK; Pallotto A; Kastenberg DM; Katz LC; Henry CH; Moleski SM; Limburg PJ; Waldman SA
    Cancer Biol Ther; 2021 Dec; 22(10-12):544-553. PubMed ID: 34632925
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. SHP2-Mediated Inhibition of DNA Repair Contributes to cGAS-STING Activation and Chemotherapeutic Sensitivity in Colon cancer.
    Wei B; Xu L; Guo W; Wang Y; Wu J; Li X; Cai X; Hu J; Wang M; Xu Q; Liu W; Gu Y
    Cancer Res; 2021 Jun; 81(12):3215-3228. PubMed ID: 33820798
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Oxaliplatin derived monofunctional triazole-containing platinum(II) complex counteracts oxaliplatin-induced drug resistance in colorectal cancer.
    Li Y; Sun Z; Cui Y; Zhang H; Zhang S; Wang X; Liu S; Gao Q
    Bioorg Chem; 2021 Feb; 107():104636. PubMed ID: 33465670
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The design and characterization of a gravitational microfluidic platform for drug sensitivity assay in colorectal perfused tumoroid cultures.
    Wang T; Green R; Howell M; Martinez T; Dutta R; Mohapatra S; Mohapatra SS
    Nanomedicine; 2020 Nov; 30():102294. PubMed ID: 32861031
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Experimental and quantum chemical study оn the DNA/protein binding and the biological activity of a rhodium(iii) complex with 1,2,4-triazole as an inert ligand.
    Petrović A; Živanović M; Puchta R; Ćoćić D; Scheurer A; Milivojevic N; Bogojeski J
    Dalton Trans; 2020 Jul; 49(26):9070-9085. PubMed ID: 32568355
    [TBL] [Abstract] [Full Text] [Related]  


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