BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND PLCG1, PLC1, 5335, ENSG00000124181, PLC-II, Plcg1, PLCgamma1, PLC148
19 results:

  • 1. Predictive and Therapeutic Implications of a Novel PLCγ1/SHP2-Driven Mechanism of Cetuximab Resistance in Metastatic colorectal cancer.
    Cruz-Duarte R; Rebelo de Almeida C; Negrão M; Fernandes A; Borralho P; Sobral D; Gallego-Paez LM; Machado D; Gramaça J; Vílchez J; Xavier AT; Ferreira MG; Miranda AR; Mansinho H; Brito MJ; Pacheco TR; Abreu C; Lucia-Costa A; Mansinho A; Fior R; Costa L; Martins M
    Clin Cancer Res; 2022 Mar; 28(6):1203-1216. PubMed ID: 34980600
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Phospholipase Cγ1 represses colorectal cancer growth by inhibiting the Wnt/β-catenin signaling axis.
    Shin KJ; Jang HJ; Lee YJ; Lee YG; Suh PG; Yang YR; Chae YC
    Biochem Biophys Res Commun; 2021 Nov; 577():103-109. PubMed ID: 34509721
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Using the Pleiotropic Characteristics of Curcumin to Validate the Potential Application of a Novel Gene Expression Screening Platform.
    Liao SC; Hsu HW; Chuang KL; Huang ZY; Lin KT; Hsu WH; Chang KH; Huang CF; Su CL
    Nutrients; 2019 Jun; 11(6):. PubMed ID: 31234318
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Inflammatory genes are novel prognostic biomarkers for colorectal cancer.
    Jiang H; Dong L; Gong F; Gu Y; Zhang H; Fan D; Sun Z
    Int J Mol Med; 2018 Jul; 42(1):368-380. PubMed ID: 29693170
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
    Dai L; Chen X; Lu X; Wang F; Zhan Y; Song G; Hu T; Xia C; Zhang B
    Sci Rep; 2017 Oct; 7(1):13912. PubMed ID: 29066806
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Fermented Herbal Formulas KIOM-MA128 Ameliorate IL-6-Induced Intestinal Barrier Dysfunction in Colon cancer Cell Line.
    Park KI; Kim DG; Lee BH; Ma JY
    Mediators Inflamm; 2016; 2016():6189590. PubMed ID: 27980357
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.
    Padhan N; Nordling TE; Sundström M; Åkerud P; Birgisson H; Nygren P; Nelander S; Claesson-Welsh L
    BMC Cancer; 2016 Aug; 16(1):683. PubMed ID: 27562229
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling.
    Guan YY; Liu HJ; Luan X; Xu JR; Lu Q; Liu YR; Gao YG; Zhao M; Chen HZ; Fang C
    Phytomedicine; 2015 Jan; 22(1):103-10. PubMed ID: 25636878
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Prognosis of lung cancer patients with a past history of colorectal cancer.
    Hattori A; Suzuki K; Aokage K; Mimae T; Nagai K; Tsuboi M; Okada M
    Jpn J Clin Oncol; 2014 Nov; 44(11):1088-95. PubMed ID: 25156681
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation.
    Zhang YM; Dai BL; Zheng L; Zhan YZ; Zhang J; Smith WW; Wang XL; Chen YN; He LC
    Cell Death Dis; 2012 Oct; 3(10):e406. PubMed ID: 23059825
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. First-degree relatives of colorectal cancer patients are likely to show advanced colorectal neoplasia despite a negative fecal immunochemical test.
    Cha JM; Lee JI; Joo KR; Shin HP; Park JJ; Jeun JW; Lim JU
    Digestion; 2012; 86(4):283-7. PubMed ID: 23051697
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Cross-talk between phospho-STAT3 and PLCγ1 plays a critical role in colorectal tumorigenesis.
    Zhang P; Zhao Y; Zhu X; Sedwick D; Zhang X; Wang Z
    Mol Cancer Res; 2011 Oct; 9(10):1418-28. PubMed ID: 21840932
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.
    Ghosh P; Beas AO; Bornheimer SJ; Garcia-Marcos M; Forry EP; Johannson C; Ear J; Jung BH; Cabrera B; Carethers JM; Farquhar MG
    Mol Biol Cell; 2010 Jul; 21(13):2338-54. PubMed ID: 20462955
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Integrative approach for prioritizing cancer genes in sporadic colon cancer.
    Reid JF; Gariboldi M; Sokolova V; Capobianco P; Lampis A; Perrone F; Signoroni S; Costa A; Leo E; Pilotti S; Pierotti MA
    Genes Chromosomes Cancer; 2009 Nov; 48(11):953-62. PubMed ID: 19672874
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Half of elderly patients routinely treated for colorectal cancer receive a sub-standard treatment.
    Aparicio T; Navazesh A; Boutron I; Bouarioua N; Chosidow D; Mion M; Choudat L; Sobhani I; Mentré F; Soulé JC
    Crit Rev Oncol Hematol; 2009 Sep; 71(3):249-57. PubMed ID: 19131256
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. [Effects of blocking phospholipase C-gamma1 signaling pathway on proliferation and apoptosis of human colorectal cancer cell line LoVo].
    Liu J; Li M; Cheng BL; Zeng WS; Zou ZP; Luo SQ
    Ai Zheng; 2007 Sep; 26(9):957-62. PubMed ID: 17927852
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. [Construction of lentivirus producing PLC-gamma1 siRNA and its effect on apoptosis of human colorectal carcinomas cell lines].
    Tan L; Luo SQ; Lin J
    Nan Fang Yi Ke Da Xue Xue Bao; 2007 Mar; 27(3):255-8. PubMed ID: 17425965
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis.
    D'Andrea MR; Mei JM; Tuman RW; Galemmo RA; Johnson DL
    Mol Cancer Ther; 2005 Aug; 4(8):1198-204. PubMed ID: 16093435
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. NF-kappaB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells.
    Li X; Hua L; Deng F; Bai X; Zeng W; Lu D; Su Y; Luo S
    Life Sci; 2005 Oct; 77(22):2794-803. PubMed ID: 15996687
    [TBL] [Abstract] [Full Text] [Related]  


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