Terms: = Colorectal cancer AND PLCG1, PLC1, 5335, ENSG00000124181, PLC-II, Plcg1, PLCgamma1, PLC148
19 results:
1. Predictive and Therapeutic Implications of a Novel PLCγ1/SHP2-Driven Mechanism of Cetuximab Resistance in Metastatic colorectal cancer.
Cruz-Duarte R; Rebelo de Almeida C; Negrão M; Fernandes A; Borralho P; Sobral D; Gallego-Paez LM; Machado D; Gramaça J; Vílchez J; Xavier AT; Ferreira MG; Miranda AR; Mansinho H; Brito MJ; Pacheco TR; Abreu C; Lucia-Costa A; Mansinho A; Fior R; Costa L; Martins M
Clin Cancer Res; 2022 Mar; 28(6):1203-1216. PubMed ID: 34980600
[TBL] [Abstract] [Full Text] [Related]
2. Phospholipase Cγ1 represses colorectal cancer growth by inhibiting the Wnt/β-catenin signaling axis.
Shin KJ; Jang HJ; Lee YJ; Lee YG; Suh PG; Yang YR; Chae YC
Biochem Biophys Res Commun; 2021 Nov; 577():103-109. PubMed ID: 34509721
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3. Using the Pleiotropic Characteristics of Curcumin to Validate the Potential Application of a Novel Gene Expression Screening Platform.
Liao SC; Hsu HW; Chuang KL; Huang ZY; Lin KT; Hsu WH; Chang KH; Huang CF; Su CL
Nutrients; 2019 Jun; 11(6):. PubMed ID: 31234318
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4. Inflammatory genes are novel prognostic biomarkers for colorectal cancer.
Jiang H; Dong L; Gong F; Gu Y; Zhang H; Fan D; Sun Z
Int J Mol Med; 2018 Jul; 42(1):368-380. PubMed ID: 29693170
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5. Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
Dai L; Chen X; Lu X; Wang F; Zhan Y; Song G; Hu T; Xia C; Zhang B
Sci Rep; 2017 Oct; 7(1):13912. PubMed ID: 29066806
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6. Fermented Herbal Formulas KIOM-MA128 Ameliorate IL-6-Induced Intestinal Barrier Dysfunction in Colon cancer Cell Line.
Park KI; Kim DG; Lee BH; Ma JY
Mediators Inflamm; 2016; 2016():6189590. PubMed ID: 27980357
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7. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.
Padhan N; Nordling TE; Sundström M; Åkerud P; Birgisson H; Nygren P; Nelander S; Claesson-Welsh L
BMC Cancer; 2016 Aug; 16(1):683. PubMed ID: 27562229
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8. Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling.
Guan YY; Liu HJ; Luan X; Xu JR; Lu Q; Liu YR; Gao YG; Zhao M; Chen HZ; Fang C
Phytomedicine; 2015 Jan; 22(1):103-10. PubMed ID: 25636878
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9. Prognosis of lung cancer patients with a past history of colorectal cancer.
Hattori A; Suzuki K; Aokage K; Mimae T; Nagai K; Tsuboi M; Okada M
Jpn J Clin Oncol; 2014 Nov; 44(11):1088-95. PubMed ID: 25156681
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10. A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation.
Zhang YM; Dai BL; Zheng L; Zhan YZ; Zhang J; Smith WW; Wang XL; Chen YN; He LC
Cell Death Dis; 2012 Oct; 3(10):e406. PubMed ID: 23059825
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11. First-degree relatives of colorectal cancer patients are likely to show advanced colorectal neoplasia despite a negative fecal immunochemical test.
Cha JM; Lee JI; Joo KR; Shin HP; Park JJ; Jeun JW; Lim JU
Digestion; 2012; 86(4):283-7. PubMed ID: 23051697
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12. Cross-talk between phospho-STAT3 and PLCγ1 plays a critical role in colorectal tumorigenesis.
Zhang P; Zhao Y; Zhu X; Sedwick D; Zhang X; Wang Z
Mol Cancer Res; 2011 Oct; 9(10):1418-28. PubMed ID: 21840932
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13. A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.
Ghosh P; Beas AO; Bornheimer SJ; Garcia-Marcos M; Forry EP; Johannson C; Ear J; Jung BH; Cabrera B; Carethers JM; Farquhar MG
Mol Biol Cell; 2010 Jul; 21(13):2338-54. PubMed ID: 20462955
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14. Integrative approach for prioritizing cancer genes in sporadic colon cancer.
Reid JF; Gariboldi M; Sokolova V; Capobianco P; Lampis A; Perrone F; Signoroni S; Costa A; Leo E; Pilotti S; Pierotti MA
Genes Chromosomes Cancer; 2009 Nov; 48(11):953-62. PubMed ID: 19672874
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15. Half of elderly patients routinely treated for colorectal cancer receive a sub-standard treatment.
Aparicio T; Navazesh A; Boutron I; Bouarioua N; Chosidow D; Mion M; Choudat L; Sobhani I; Mentré F; Soulé JC
Crit Rev Oncol Hematol; 2009 Sep; 71(3):249-57. PubMed ID: 19131256
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16. [Effects of blocking phospholipase C-gamma1 signaling pathway on proliferation and apoptosis of human colorectal cancer cell line LoVo].
Liu J; Li M; Cheng BL; Zeng WS; Zou ZP; Luo SQ
Ai Zheng; 2007 Sep; 26(9):957-62. PubMed ID: 17927852
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17. [Construction of lentivirus producing PLC-gamma1 siRNA and its effect on apoptosis of human colorectal carcinomas cell lines].
Tan L; Luo SQ; Lin J
Nan Fang Yi Ke Da Xue Xue Bao; 2007 Mar; 27(3):255-8. PubMed ID: 17425965
[TBL] [Abstract] [Full Text] [Related]
18. Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis.
D'Andrea MR; Mei JM; Tuman RW; Galemmo RA; Johnson DL
Mol Cancer Ther; 2005 Aug; 4(8):1198-204. PubMed ID: 16093435
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19. NF-kappaB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells.
Li X; Hua L; Deng F; Bai X; Zeng W; Lu D; Su Y; Luo S
Life Sci; 2005 Oct; 77(22):2794-803. PubMed ID: 15996687
[TBL] [Abstract] [Full Text] [Related]