Terms: = Colorectal cancer AND POLE, POLE1, 5426, FLJ21434, DKFZp434F222, ENSG00000177084 AND Treatment
70 results:
1. PD-1 blockade enhances the effect of targeted chemotherapy on locally advanced pMMR/MSS colorectal cancer.
Pei F; He W; Duan Y; Yao Q; Zhao Y; Fan X; Liu S; Chen H; He F; Liu T; Chen J; Zheng Y; Li H; Guo X; Shi L; Ling L; Chen Y; He J; Liu M; Huang M; Bai Y; Wang J; Huang M; Huang J
Cancer Med; 2024 Jun; 13(12):e7224. PubMed ID: 38888366
[TBL] [Abstract] [Full Text] [Related]
2. Neoadjuvant camrelizumab plus apatinib for locally advanced microsatellite instability-high or mismatch repair-deficient colorectal cancer (NEOCAP): a single-arm, open-label, phase 2 study.
Yu JH; Xiao BY; Li DD; Jiang W; Ding Y; Wu XJ; Zhang RX; Lin JZ; Wang W; Han K; Kong LH; Zhang XK; Chen BY; Mei WJ; Pan ZZ; Tang JH; Zhang XS; Ding PR
Lancet Oncol; 2024 Jul; 25(7):843-852. PubMed ID: 38852601
[TBL] [Abstract] [Full Text] [Related]
3. Immune checkpoint inhibitors for pole or POLD1 proofreading-deficient metastatic colorectal cancer.
Ambrosini M; Rousseau B; Manca P; Artz O; Marabelle A; André T; Maddalena G; Mazzoli G; Intini R; Cohen R; Cercek A; Segal NH; Saltz L; Varghese AM; Yaeger R; Nusrat M; Goldberg Z; Ku GY; El Dika I; Margalit O; Grinshpun A; Murtaza Kasi P; Schilsky R; Lutfi A; Shacham-Shmueli E; Khan Afghan M; Weiss L; Westphalen CB; Conca V; Decker B; Randon G; Elez E; Fakih M; Schrock AB; Cremolini C; Jayachandran P; Overman MJ; Lonardi S; Pietrantonio F
Ann Oncol; 2024 Jul; 35(7):643-655. PubMed ID: 38777726
[TBL] [Abstract] [Full Text] [Related]
4. Distinct Driver Pathway Enrichments and a High Prevalence of
Tapia-Valladares C; Valenzuela G; González E; Maureira I; Toro J; Freire M; Sepúlveda-Hermosilla G; Ampuero D; Blanco A; Gallegos I; Morales F; Erices JI; Barajas O; Ahumada M; Contreras HR; González J; Armisén R; Marcelain K
Int J Mol Sci; 2024 Apr; 25(9):. PubMed ID: 38731914
[TBL] [Abstract] [Full Text] [Related]
5. Molecular characterization as new driver in prognostic signatures and therapeutic strategies for endometrial cancer.
D'Agostino E; Mastrodomenico L; Ponzoni O; Baldessari C; Piombino C; Pipitone S; Giuseppa Vitale M; Sabbatini R; Dominici M; Toss A
Cancer Treat Rev; 2024 May; 126():102723. PubMed ID: 38555857
[TBL] [Abstract] [Full Text] [Related]
6. Multiple duodenal epithelial tumors in a patient with polymerase proofreading-associated polyposis in pole variant.
Miyazaki H; Dohi O; Maeda E; Tomioka A; Yoshida N; Morinaga Y; Itoh Y; Ishikawa H
Clin J Gastroenterol; 2024 Jun; 17(3):425-428. PubMed ID: 38386255
[TBL] [Abstract] [Full Text] [Related]
7. Multiomic molecular characterization of the response to combination immunotherapy in MSS/pMMR metastatic colorectal cancer.
Takei S; Tanaka Y; Lin YT; Koyama S; Fukuoka S; Hara H; Nakamura Y; Kuboki Y; Kotani D; Kojima T; Bando H; Mishima S; Ueno T; Kojima S; Wakabayashi M; Sakamoto N; Kojima M; Kuwata T; Yoshino T; Nishikawa H; Mano H; Endo I; Shitara K; Kawazoe A
J Immunother Cancer; 2024 Feb; 12(2):. PubMed ID: 38336371
[TBL] [Abstract] [Full Text] [Related]
8. Exploring Co-occurring pole Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity.
Shah SM; Demidova EV; Ringenbach S; Faezov B; Andrake M; Gandhi A; Mur P; Viana-Errasti J; Xiu J; Swensen J; Valle L; Dunbrack RL; Hall MJ; Arora S
Cancer Res Commun; 2024 Jan; 4(1):213-225. PubMed ID: 38282550
[TBL] [Abstract] [Full Text] [Related]
9. Caecal malakoplakia: a rare mimic of malignancy.
Li Voon Chong J; Ali N
BMJ Case Rep; 2024 Jan; 17(1):. PubMed ID: 38262716
[TBL] [Abstract] [Full Text] [Related]
10. Antitumor Activity and Safety of Dostarlimab Monotherapy in Patients With Mismatch Repair Deficient Solid Tumors: A Nonrandomized Controlled Trial.
André T; Berton D; Curigliano G; Sabatier R; Tinker AV; Oaknin A; Ellard S; de Braud F; Arkenau HT; Trigo J; Gravina A; Kristeleit R; Moreno V; Abdeddaim C; Vano YA; Samouëlian V; Miller R; Boni V; Torres AA; Gilbert L; Brown J; Dewal N; Dabrowski C; Antony G; Zografos E; Veneris J; Banerjee S
JAMA Netw Open; 2023 Nov; 6(11):e2341165. PubMed ID: 37917058
[TBL] [Abstract] [Full Text] [Related]
11. Exploring the basis of heterogeneity of cancer aggressiveness among the mutated pole variants.
Selves J; de Castro E Gloria H; Brunac AC; Saffi J; Guimbaud R; Brousset P; Hoffmann JS
Life Sci Alliance; 2024 Jan; 7(1):. PubMed ID: 37891003
[TBL] [Abstract] [Full Text] [Related]
12. pole-Mutant Colon cancer Treated with PD-1 Blockade Showing Clearance of Circulating Tumor DNA and Prolonged Disease-Free Interval.
Bikhchandani M; Amersi F; Hendifar A; Gangi A; Osipov A; Zaghiyan K; Atkins K; Cho M; Aguirre F; Hazelett D; Alvarez R; Zhou L; Hitchins M; Gong J
Genes (Basel); 2023 May; 14(5):. PubMed ID: 37239414
[TBL] [Abstract] [Full Text] [Related]
13. Immune Checkpoint Inhibitors in pMMR/MSS colorectal cancer.
El Hajj J; Reddy S; Verma N; Huang EH; Kazmi SM
J Gastrointest Cancer; 2023 Dec; 54(4):1017-1030. PubMed ID: 37009977
[TBL] [Abstract] [Full Text] [Related]
14. Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study.
Wang J; Xiu J; Farrell A; Baca Y; Arai H; Battaglin F; Kawanishi N; Soni S; Zhang W; Millstein J; Shields AF; Grothey A; Weinberg BA; Marshall JL; Lou E; Khushman M; Sohal DPS; Hall MJ; Liu T; Oberley M; Spetzler D; Korn WM; Shen L; Lenz HJ
Lancet Oncol; 2023 Feb; 24(2):151-161. PubMed ID: 36681091
[TBL] [Abstract] [Full Text] [Related]
15. Pathological complete response to immune checkpoint inhibitor in patients with colorectal cancer liver metastases harboring
Wen L; Chen Z; Ji X; Fong WP; Shao Q; Ren C; Cai Y; Li B; Yuan Y; Wang D; Li Y
J Immunother Cancer; 2022 Jul; 10(7):. PubMed ID: 35793867
[TBL] [Abstract] [Full Text] [Related]
16. Comprehensive genomic profiling in advanced/metastatic colorectal cancer: number needed to test and budget impact of expanded first line use.
Proudman D; DeVito NC; Belinson S; Allo MA; Morris ED; Signorovitch J; Patel AK
J Med Econ; 2022; 25(1):817-825. PubMed ID: 35593483
[TBL] [Abstract] [Full Text] [Related]
17. NTRK fusion positive colorectal cancer is a unique subset of CRC with high TMB and microsatellite instability.
Wang H; Li ZW; Ou Q; Wu X; Nagasaka M; Shao Y; Ou SI; Yang Y
Cancer Med; 2022 Jul; 11(13):2541-2549. PubMed ID: 35506567
[TBL] [Abstract] [Full Text] [Related]
18. FOLFOXIRI and bevacizumab in patients with early-onset metastatic colorectal cancer. A pooled analysis of TRIBE and TRIBE2 studies.
Antoniotti C; Germani MM; Rossini D; Lonardi S; Pietrantonio F; Santini D; Marmorino F; Allegrini G; Daniel F; Raimondi A; Borelli B; Zaniboni A; Conca V; Abraham J; Spetzler D; Maiello E; Boccaccino A; Passardi A; Giordano M; Tamburini E; Korn MW; Masi G; Cremolini C
Eur J Cancer; 2022 May; 167():23-31. PubMed ID: 35366570
[TBL] [Abstract] [Full Text] [Related]
19. The Current and Evolving Role of Immunotherapy in Metastatic colorectal cancer.
Silva VS; Riechelmann RP; Mello CA; Felismino T; Taboada R
Curr Cancer Drug Targets; 2022 Aug; 22(8):617-628. PubMed ID: 35209820
[TBL] [Abstract] [Full Text] [Related]
20. Phase II study of durvalumab monotherapy in patients with previously treated microsatellite instability-high/mismatch repair-deficient or pole-mutated metastatic or unresectable colorectal cancer.
Oh CR; Kim JE; Hong YS; Kim SY; Ahn JB; Baek JY; Lee MA; Kang MJ; Cho SH; Beom SH; Kim TW
Int J Cancer; 2022 Jun; 150(12):2038-2045. PubMed ID: 35179785
[TBL] [Abstract] [Full Text] [Related]
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