Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND PPM1D, Wip1, 8493, ENSG00000170836, O15297, WIP1, PP2C-DELTA
20 results:

  • 1. Changes in the Transcriptome Caused by Mutations in the Ribosomal Protein uS10 Associated with a Predisposition to colorectal cancer.
    Tian Y; Babaylova ES; Gopanenko AV; Tupikin AE; Kabilov MR; Malygin AA; Karpova GG
    Int J Mol Sci; 2022 May; 23(11):. PubMed ID: 35682850
    [TBL] [Abstract] [Full Text] [Related]  

  • 2.
    Stolarova L; Kleiblova P; Janatova M; Soukupova J; Zemankova P; Macurek L; Kleibl Z
    Cells; 2020 Dec; 9(12):. PubMed ID: 33322746
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Truncated ppm1d impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.
    Burocziova M; Burdova K; Martinikova AS; Kasparek P; Kleiblova P; Danielsen SA; Borecka M; Jenikova G; Janečková L; Pavel J; Zemankova P; Schneiderova M; Schwarzova L; Ticha I; Sun XF; Jiraskova K; Liska V; Vodickova L; Vodicka P; Sedlacek R; Kleibl Z; Lothe RA; Korinek V; Macurek L
    Cell Death Dis; 2019 Oct; 10(11):818. PubMed ID: 31659152
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Silencing of PPMD1 inhibits proliferation of human colon cancer cells via induction of apoptosis and cell cycle arrest.
    Yin Z; Yi J; Nie T; Yang Z; Ding N; Du SX; Liu S; Peng T
    J BUON; 2019; 24(4):1464-1469. PubMed ID: 31646792
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. wip1 cooperates with KPNA2 to modulate the cell proliferation and migration of colorectal cancer via a p53-dependent manner.
    Wang P; Zhao Y; Liu K; Liu X; Liang J; Zhou H; Wang Z; Zhou Z; Xu N
    J Cell Biochem; 2019 Sep; 120(9):15709-15718. PubMed ID: 31127650
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. NF-κB-induced wip1 expression promotes colorectal cancer cell proliferation through mTOR signaling.
    Bai F; Zhou H; Fu Z; Xie J; Hu Y; Nie S
    Biomed Pharmacother; 2018 Mar; 99():402-410. PubMed ID: 29367109
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Truncating and missense ppm1d mutations in early-onset and/or familial/hereditary prostate cancer patients.
    Cardoso M; Paulo P; Maia S; Teixeira MR
    Genes Chromosomes Cancer; 2016 Dec; 55(12):954-961. PubMed ID: 27401275
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Usefulness of dilated blood vessels in the tumor periphery for assessing the invasion depth of small-sized depressed colorectal cancer.
    Hashimoto R; Matsuda T; Hamamoto H; Yamaoka H; Nakahori M; Chonan A
    Medicine (Baltimore); 2016 Jun; 95(25):e3913. PubMed ID: 27336879
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Wee1 inhibition potentiates wip1-dependent p53-negative tumor cell death during chemotherapy.
    Clausse V; Goloudina AR; Uyanik B; Kochetkova EY; Richaud S; Fedorova OA; Hammann A; Bardou M; Barlev NA; Garrido C; Demidov ON
    Cell Death Dis; 2016 Apr; 7(4):e2195. PubMed ID: 27077811
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. ppm1d phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38.
    Zhang M; Xu E; Zhang J; Chen X
    Oncogene; 2015 Nov; 34(48):5900-11. PubMed ID: 25823026
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Truncating mutations of ppm1d are found in blood DNA samples of lung cancer patients.
    Zajkowicz A; Butkiewicz D; Drosik A; Giglok M; Suwiński R; Rusin M
    Br J Cancer; 2015 Mar; 112(6):1114-20. PubMed ID: 25742468
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Inhibition of C-terminal truncated ppm1d enhances the effect of doxorubicin on cell viability in human colorectal carcinoma cell line.
    Kozakai Y; Kamada R; Kiyota Y; Yoshimura F; Tanino K; Sakaguchi K
    Bioorg Med Chem Lett; 2014 Dec; 24(24):5593-5596. PubMed ID: 25466181
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Knockdown of protein phosphatase magnesium-dependent 1 (ppm1d) through lentivirus-mediated RNA silencing inhibits colorectal carcinoma cell proliferation.
    Yin H; Yan Z; Liang Y; Liu B; Su Q
    Technol Cancer Res Treat; 2013 Dec; 12(6):537-43. PubMed ID: 23745790
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Expression and significance of the wip1 proto-oncogene in colorectal cancer.
    Li ZT; Zhang L; Gao XZ; Jiang XH; Sun LQ
    Asian Pac J Cancer Prev; 2013; 14(3):1975-9. PubMed ID: 23679302
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Gain-of-function mutations of ppm1d/wip1 impair the p53-dependent G1 checkpoint.
    Kleiblova P; Shaltiel IA; Benada J; Ševčík J; Pecháčková S; Pohlreich P; Voest EE; Dundr P; Bartek J; Kleibl Z; Medema RH; Macurek L
    J Cell Biol; 2013 May; 201(4):511-21. PubMed ID: 23649806
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Duodenal surveillance improves the prognosis after duodenal cancer in familial adenomatous polyposis.
    Bülow S; Christensen IJ; Højen H; Björk J; Elmberg M; Järvinen H; Lepistö A; Nieuwenhuis M; Vasen H
    Colorectal Dis; 2012 Aug; 14(8):947-52. PubMed ID: 21973191
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response.
    Cha H; Lowe JM; Li H; Lee JS; Belova GI; Bulavin DV; Fornace AJ
    Cancer Res; 2010 May; 70(10):4112-22. PubMed ID: 20460517
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. p53 Regulates LIF expression in human medulloblastoma cells.
    Baxter EW; Milner J
    J Neurooncol; 2010 May; 97(3):373-82. PubMed ID: 19907922
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The wip1 phosphatase (ppm1d) antagonizes activation of the Chk2 tumour suppressor kinase.
    Oliva-Trastoy M; Berthonaud V; Chevalier A; Ducrot C; Marsolier-Kergoat MC; Mann C; Leteurtre F
    Oncogene; 2007 Mar; 26(10):1449-58. PubMed ID: 16936775
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers.
    Kanai Y; Ushijima S; Saito Y; Nakanishi Y; Sakamoto M; Hirohashi S
    J Cancer Res Clin Oncol; 2001 Dec; 127(12):697-706. PubMed ID: 11768609
    [TBL] [Abstract] [Full Text] [Related]  

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