Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND PTCH1, RP11-435O5_3, Q13635, PTCH, 5727, HPE7, FLJ26746, NBCCS, BCNS, PTC1, ENSG00000185920, FLJ42602
61 results:

  • 1. Co-Occurrence of Germline Genomic Variants and Copy Number Variations in Hereditary Breast and colorectal cancer Patients.
    Côrtes L; Basso TR; Villacis RAR; Souza JDS; Jørgensen MMA; Achatz MI; Rogatto SR
    Genes (Basel); 2023 Aug; 14(8):. PubMed ID: 37628631
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. First report of medulloblastoma in a patient with MUTYH-associated polyposis.
    Villy MC; Warcoin M; Filser M; Buecher B; Golmard L; Suybeng V; Schwartz M; Bieche I; Vacher S; Laurence V; Bourdeaut F; Bernier M; Gutman T; Stoppa-Lyonnet D; Masliah-Planchon J; Colas C
    Neuropathol Appl Neurobiol; 2023 Aug; 49(4):e12929. PubMed ID: 37524406
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Targeting the Hedgehog pathway with novel Gli1 hydrophobic tagging degraders.
    Li X; Sun R; Wu H; Zheng C; Long YQ
    Bioorg Chem; 2023 Sep; 138():106649. PubMed ID: 37307715
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Canonical and uncanonical pathogenic germline variants in colorectal cancer patients by next-generation sequencing in a European referral center.
    Poliani L; Greco L; Barile M; Dal Buono A; Bianchi P; Basso G; Giatti V; Genuardi M; Malesci A; Laghi L;
    ESMO Open; 2022 Dec; 7(6):100607. PubMed ID: 36356413
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Cerebellar liponeurocytoma: clinical, histopathological and molecular features of a series of three cases, including one recurrent tumor.
    Broggi G; Tirrò E; Alzoubi H; Arcella A; Gianno F; Antonelli M; Minasi S; Vigneri P; Certo F; Altieri R; Barbagallo GMV; Miele E; Caltabiano R; Giangaspero F
    Neuropathology; 2022 Jun; 42(3):169-180. PubMed ID: 35042275
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Application of Multigene Panel Testing in Patients With High Risk for Hereditary colorectal cancer: A Descriptive Report Focused on Genotype-Phenotype Correlation.
    Park JS; Park JW; Shin S; Lee ST; Shin SJ; Min BS; Park SJ; Park JJ; Cheon JH; Kim WH; Kim TI
    Dis Colon Rectum; 2022 Jun; 65(6):793-803. PubMed ID: 34897210
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. [Difference analysis of somatic mutations between deficient mismatch repair and proficient mismatch repair gene related with colorectal cancer].
    Tang XJ; Yang MY; Zhu LZ; Xu D; Yuan Y
    Zhonghua Zhong Liu Za Zhi; 2021 Oct; 43(10):1088-1093. PubMed ID: 34695900
    [No Abstract]    [Full Text] [Related]  

  • 8. ptch1 mutation promotes antitumor immunity and the response to immune checkpoint inhibitors in colorectal cancer patients.
    Wang Y; Chen H; Jiao X; Wu L; Yang Y; Zhang J; Wu L; Liu C; Zhuo N; Li S; Gong J; Li J; Zhang X; Wang X; Peng Z; Qi C; Wang Z; Li J; Li Y; Lu Z; Zhang H; Shen L
    Cancer Immunol Immunother; 2022 Jan; 71(1):111-120. PubMed ID: 34028566
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. [Mechanism of ursolic acid in regulating colorectal cancer cell HCT116 autophagy through hedgehog signaling pathway].
    He M; Zhang M; Sun Q; Zeng S; Chen L; Zhao H; Yang H; Liu ML; Ren S; Xu HB
    Zhongguo Zhong Yao Za Zhi; 2021 Mar; 46(5):1217-1223. PubMed ID: 33787118
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression.
    Cui H; Yu W; Yu M; Luo Y; Yang M; Cong R; Chu X; Gao G; Zhong M
    Cancer Sci; 2021 May; 112(5):1798-1810. PubMed ID: 33629464
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Hedgehog Signaling in colorectal cancer: All in the Stroma?
    Geyer N; Gerling M
    Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33498528
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The Role of Smoothened in cancer.
    Jeng KS; Sheen IS; Leu CM; Tseng PH; Chang CF
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32962123
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis.
    Lai Q; Li Q; He C; Fang Y; Lin S; Cai J; Ding J; Zhong Q; Zhang Y; Wu C; Wang X; He J; Liu Y; Yan Q; Li A; Liu S
    Aging (Albany NY); 2020 Jul; 12(16):16270-16293. PubMed ID: 32688344
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Age, sex, and specific gene mutations affect the effects of immune checkpoint inhibitors in colorectal cancer.
    Lin A; Zhang H; Hu X; Chen X; Wu G; Luo P; Zhang J
    Pharmacol Res; 2020 Sep; 159():105028. PubMed ID: 32569820
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Genomic testing, tumor microenvironment and targeted therapy of Hedgehog-related human cancers.
    Katoh M
    Clin Sci (Lond); 2019 Apr; 133(8):953-970. PubMed ID: 31036756
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. A RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer.
    Yamada A; Yu P; Lin W; Okugawa Y; Boland CR; Goel A
    Sci Rep; 2018 Jan; 8(1):575. PubMed ID: 29330370
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon cancer Stem Cells.
    Regan JL; Schumacher D; Staudte S; Steffen A; Haybaeck J; Keilholz U; Schweiger C; Golob-Schwarzl N; Mumberg D; Henderson D; Lehrach H; Regenbrecht CRA; Schäfer R; Lange M
    Cell Rep; 2017 Dec; 21(10):2813-2828. PubMed ID: 29212028
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. A mutational comparison of adult and adolescent and young adult (AYA) colon cancer.
    Tricoli JV; Boardman LA; Patidar R; Sindiri S; Jang JS; Walsh WD; McGregor PM; Camalier CE; Mehaffey MG; Furman WL; Bahrami A; Williams PM; Lih CJ; Conley BA; Khan J
    Cancer; 2018 Mar; 124(5):1070-1082. PubMed ID: 29194591
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.
    Slattery ML; Herrick JS; Mullany LE; Samowitz WS; Sevens JR; Sakoda L; Wolff RK
    Genes Chromosomes Cancer; 2017 Nov; 56(11):769-787. PubMed ID: 28675510
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. FOXR2 Promotes the Proliferation, Invasion, and Epithelial-Mesenchymal Transition in Human colorectal cancer Cells.
    Lu SQ; Qiu Y; Dai WJ; Zhang XY
    Oncol Res; 2017 May; 25(5):681-689. PubMed ID: 28548041
    [TBL] [Abstract] [Full Text] [Related]  


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