Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
32 results:

  • 1. Identification and analysis of the molecular targets of statins in colorectal cancer.
    Firouzjaei AA; Mahmoudi A; Almahmeed W; Teng Y; Kesharwani P; Sahebkar A
    Pathol Res Pract; 2024 Apr; 256():155258. PubMed ID: 38522123
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Tumor pH-functionalized and charge-tunable nanoparticles for the nucleus/cytoplasm-directed delivery of oxaliplatin and miRNA in the treatment of head and neck cancer.
    Lo YL; Lin HC; Tseng WH
    Acta Biomater; 2022 Nov; 153():465-480. PubMed ID: 36115656
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. ARHGAP17 enhances 5-Fluorouracil-induced apoptosis in colon cancer cells by suppressing rac1.
    Pan SL; Deng YY; Fu J; Zhang YH; Zhang ZJ; Qin XJ
    Neoplasma; 2022 May; 69(3):640-647. PubMed ID: 35293764
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  • 4. Downregulation of rac1/PAK1/LIMK1/cofilin signaling pathway in colon cancer SW620 cells treated with Chlorin e6 photodynamic therapy.
    Wufuer R; Ma HX; Luo MY; Xu KY; Kang L
    Photodiagnosis Photodyn Ther; 2021 Mar; 33():102143. PubMed ID: 33307230
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. PAK5 facilitates the proliferation, invasion and migration in colorectal cancer cells.
    Huang S; Zhu Y; Wang C; Li X; Cui X; Tu S; You L; Fu J; Chen Z; Hu W; Gong W
    Cancer Med; 2020 Jul; 9(13):4777-4790. PubMed ID: 32383357
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  • 6. Recent Advances in Pathology: the 2020 Annual Review Issue of The Journal of Pathology.
    Herrington CS; Poulsom R; Coates PJ
    J Pathol; 2020 Apr; 250(5):475-479. PubMed ID: 32346919
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  • 7. POTEE promotes colorectal carcinoma progression via activating the rac1/Cdc42 pathway.
    Xu Q; Chen J; Peng M; Duan S; Hu Y; Guo D; Geng J; Zhou J
    Exp Cell Res; 2020 May; 390(1):111933. PubMed ID: 32142855
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Organ preservation with chemoradiotherapy plus local excision for rectal cancer: 5-year results of the GRECCAR 2 randomised trial.
    Rullier E; Vendrely V; Asselineau J; Rouanet P; Tuech JJ; Valverde A; de Chaisemartin C; Rivoire M; Trilling B; Jafari M; Portier G; Meunier B; Sieleznieff I; Bertrand M; Marchal F; Dubois A; Pocard M; Rullier A; Smith D; Frulio N; Frison E; Denost Q
    Lancet Gastroenterol Hepatol; 2020 May; 5(5):465-474. PubMed ID: 32043980
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  • 9. ΔNp63α suppresses cells invasion by downregulating PKCγ/rac1 signaling through miR-320a.
    Aljagthmi AA; Hill NT; Cooke M; Kazanietz MG; Abba MC; Long W; Kadakia MP
    Cell Death Dis; 2019 Sep; 10(9):680. PubMed ID: 31515469
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. rac1b Overexpression Confers Resistance to Chemotherapy treatment in colorectal cancer.
    Goka ET; Chaturvedi P; Lopez DTM; Garza A; Lippman ME
    Mol Cancer Ther; 2019 May; 18(5):957-968. PubMed ID: 30926638
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Roles of CD133 in microvesicle formation and oncoprotein trafficking in colon cancer.
    Kang M; Kim S; Ko J
    FASEB J; 2019 Mar; 33(3):4248-4260. PubMed ID: 30521383
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Verbascoside Attenuates Rac-1 and HIF-1α Signaling Cascade in colorectal cancer Cells.
    Seyfi D; Behzad SB; Nabiuni M; Parivar K; Tahmaseb M; Amini E
    Anticancer Agents Med Chem; 2018; 18(15):2149-2155. PubMed ID: 29886834
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The ILK-MMP9-MRTF axis is crucial for EndMT differentiation of endothelial cells in a tumor microenvironment.
    Ciszewski WM; Sobierajska K; Wawro ME; Klopocka W; Chefczyńska N; Muzyczuk A; Siekacz K; Wujkowska A; Niewiarowska J
    Biochim Biophys Acta Mol Cell Res; 2017 Dec; 1864(12):2283-2296. PubMed ID: 28893556
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.
    Kai M; Yamamoto E; Sato A; Yamano HO; Niinuma T; Kitajima H; Harada T; Aoki H; Maruyama R; Toyota M; Hatahira T; Nakase H; Sugai T; Yamashita T; Toyota M; Suzuki H
    Mol Carcinog; 2017 Jul; 56(7):1743-1752. PubMed ID: 28218473
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  • 15. Molecular characteristics of recurrent triple-negative breast cancer.
    Tsai CH; Chiu JH; Yang CW; Wang JY; Tsai YF; Tseng LM; Chen WS; Shyr YM
    Mol Med Rep; 2015 Nov; 12(5):7326-34. PubMed ID: 26458489
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers.
    He S; Zhao Z; Yang Y; O'Connell D; Zhang X; Oh S; Ma B; Lee JH; Zhang T; Varghese B; Yip J; Dolatshahi Pirooz S; Li M; Zhang Y; Li GM; Ellen Martin S; Machida K; Liang C
    Nat Commun; 2015 Aug; 6():7839. PubMed ID: 26234763
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Gene silencing of rac1 with RNA interference mediated by ultrasound and microbubbles in human LoVo cells: evaluation of cell invasion inhibition and metastatic.
    Nie F; Wang XF; Zhao SY; Bu L; Liu XH
    J Drug Target; 2015 May; 23(4):380-6. PubMed ID: 25673262
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Radixin enhances colon cancer cell invasion by increasing MMP-7 production via rac1-ERK pathway.
    Jiang QH; Wang AX; Chen Y
    ScientificWorldJournal; 2014; 2014():340271. PubMed ID: 25136657
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  • 19. rac1b overexpression correlates with poor prognosis in KRAS/BRAF WT metastatic colorectal cancer patients treated with first-line FOLFOX/XELOX chemotherapy.
    Alonso-Espinaco V; Cuatrecasas M; Alonso V; Escudero P; Marmol M; Horndler C; Ortego J; Gallego R; Codony-Servat J; Garcia-Albeniz X; Jares P; Castells A; Lozano JJ; Rosell R; Maurel J
    Eur J Cancer; 2014 Jul; 50(11):1973-81. PubMed ID: 24833563
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.
    Zins K; Gunawardhana S; Lucas T; Abraham D; Aharinejad S
    J Transl Med; 2013 Nov; 11():295. PubMed ID: 24279335
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