Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND RAF1, Raf-1, 5894, P04049, ENSG00000132155, c-Raf, CRAF
149 results:

  • 1. The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression.
    Jin H; Huang X; Pan Q; Ma N; Xie X; Wei Y; Yu F; Wen W; Zhang B; Zhang P; Chen X; Wang J; Liu RY; Lin J; Meng X; Lee MH
    Nat Commun; 2024 Mar; 15(1):2551. PubMed ID: 38514606
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Site specific genetic differences in colorectal cancer via Next-Generation-Sequencing using a multigene panel.
    Rencuzogullari A; Bisgin A; Erdogan KE; Gumus S; Yalav O; Boga I; Sonmezler O; Eray IC
    Ann Ital Chir; 2023; 94():605-611. PubMed ID: 38131395
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. 1,8-Dihydroxy-3-methoxy-anthraquinone inhibits tumor angiogenesis through HIF-1α downregulation.
    Hwang SJ; Cho SH; Bang HJ; Hong JH; Kim KH; Lee HJ
    Biochem Pharmacol; 2024 Feb; 220():115972. PubMed ID: 38072164
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A phase I, single-center, open-label study to investigate the absorption, distribution, metabolism and excretion of encorafenib following a single oral dose of 100 mg [
    Wollenberg L; Hahn E; Williams J; Litwiler K
    Pharmacol Res Perspect; 2023 Oct; 11(5):e01140. PubMed ID: 37775918
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Predictive Genetic Biomarkers for the Development of Peritoneal Metastases in colorectal cancer.
    Heuvelings DJI; Wintjens AGWE; Moonen L; Engelen SME; de Hingh IHJT; Valkenburg-van Iersel LB; den Dulk M; Beckervordersandforth J; Thijssen SGM; Leunissen DJG; Stassen LPS; Keszthelyi D; Mujagic Z; Speel EM; Bouvy ND
    Int J Mol Sci; 2023 Aug; 24(16):. PubMed ID: 37629011
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. KRAS Pathways: A Potential Gateway for cancer Therapeutics and Diagnostics.
    Tripathi PK; Mittal KR; Jain N; Sharma N; Jain CK
    Recent Pat Anticancer Drug Discov; 2024; 19(3):268-279. PubMed ID: 37038676
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  • 7. raf1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status.
    Dorard C; Madry C; Buhard O; Toifl S; Didusch S; Ratovomanana T; Letourneur Q; Dolznig H; Garnett MJ; Duval A; Baccarini M
    Oncogene; 2023 May; 42(20):1649-1660. PubMed ID: 37020037
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  • 8. Erianin suppresses constitutive activation of MAPK signaling pathway by inhibition of craf and MEK1/2.
    Wang P; Jia X; Lu B; Huang H; Liu J; Liu X; Wu Q; Hu Y; Li P; Wei H; Liu T; Zhao D; Zhang L; Tian X; Jiang Y; Qiao Y; Nie W; Ma X; Bai R; Peng C; Dong Z; Liu K
    Signal Transduct Target Ther; 2023 Mar; 8(1):96. PubMed ID: 36872366
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Melatonin-Assisted Cisplatin Suppresses Urinary Bladder cancer Cell Proliferation and Growth through Inhibiting PrP
    Yang CC; Chuang FC; Chang CL; Huang CR; Chen HH; Yip HK; Chen YT
    Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36834767
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study.
    Wang J; Xiu J; Farrell A; Baca Y; Arai H; Battaglin F; Kawanishi N; Soni S; Zhang W; Millstein J; Shields AF; Grothey A; Weinberg BA; Marshall JL; Lou E; Khushman M; Sohal DPS; Hall MJ; Liu T; Oberley M; Spetzler D; Korn WM; Shen L; Lenz HJ
    Lancet Oncol; 2023 Feb; 24(2):151-161. PubMed ID: 36681091
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. α4-α5 Helices on Surface of KRAS Can Accommodate Small Compounds That Increase KRAS Signaling While Inducing CRC Cell Death.
    Abuasaker B; Garrido E; Vilaplana M; Gómez-Zepeda JD; Brun S; Garcia-Cajide M; Mauvezin C; Jaumot M; Pujol MD; Rubio-Martínez J; Agell N
    Int J Mol Sci; 2023 Jan; 24(1):. PubMed ID: 36614192
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The sodium channel subunit SCNN1B suppresses colorectal cancer via suppression of active c-raf and MAPK signaling cascade.
    Qian Y; Zhou L; Luk STY; Xu J; Li W; Gou H; Chen H; Kang W; Yu J; Wong CC
    Oncogene; 2023 Feb; 42(8):601-612. PubMed ID: 36564468
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Anticancer Properties of Selenium-Enriched Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), in Colon cancer In Vitro.
    Fekry T; Salem MF; Abd-Elaziz AA; Muawia S; Naguib YM; Khalil H
    Int J Med Mushrooms; 2022; 24(11):1-20. PubMed ID: 36374945
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The tumour/normal tissue ratio of Keap1 protein is a predictor for lymphovascular invasion in colorectal cancer: a correlation study between the Nrf2 and KRas pathways.
    Chang LC; Fan CW; Tseng WK; Chen JR; Hua CC
    Biomarkers; 2022 Nov; 27(7):701-707. PubMed ID: 35830714
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Circ_CDR1as: A circular RNA with roles in the carcinogenesis.
    Ghafouri-Fard S; Khoshbakht T; Hussen BM; Sarfaraz S; Taheri M; Ayatollahi SA
    Pathol Res Pract; 2022 Aug; 236():153968. PubMed ID: 35667198
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  • 16.
    Pan X; Hou X; Zhang F; Tang P; Wan W; Su Z; Yang Y; Wei W; Du Z; Deng J; Hao E
    Pharm Biol; 2022 Dec; 60(1):915-930. PubMed ID: 35587342
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Anticancer drug resistance: An update and perspective.
    Nussinov R; Tsai CJ; Jang H
    Drug Resist Updat; 2021 Dec; 59():100796. PubMed ID: 34953682
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. STOML2 interacts with PHB through activating MAPK signaling pathway to promote colorectal cancer proliferation.
    Ma W; Chen Y; Xiong W; Li W; Xu Z; Wang Y; Wei Z; Mou T; Wu Z; Cheng M; Zou Y; Zhu Y; Zhou W; Liu F; Geng Y
    J Exp Clin Cancer Res; 2021 Nov; 40(1):359. PubMed ID: 34781982
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma.
    Al Shahrani M; Abohassan M; Y Alshahrani M; Hakami AR; Rajagopalan P
    J Comput Aided Mol Des; 2021 Dec; 35(12):1165-1176. PubMed ID: 34727304
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Combined high energy of extracorporeal shock wave and 5-FU effectively suppressed the proliferation and growth of tongue squamous cell carcinoma.
    Chang CL; Chen KH; Sung PH; Chiang JY; Huang CR; Chen HH; Yip HK
    Biomed Pharmacother; 2021 Oct; 142():112036. PubMed ID: 34411913
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