Terms: = Colorectal cancer AND RSPO2, Q6UXX9, 340419, ENSG00000147655, MGC43342, MGC35555
22 results:
1. CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer.
Tejedor JR; Peñarroya A; Gancedo-Verdejo J; Santamarina-Ojeda P; Pérez RF; López-Tamargo S; Díez-Borge A; Alba-Linares JJ; González-Del-Rey N; Urdinguio RG; Mangas C; Roberti A; López V; Morales-Ruiz T; Ariza RR; Roldán-Arjona T; Meijón M; Valledor L; Cañal MJ; Fernández-Martínez D; Fernández-Hevia M; Jiménez-Fonseca P; García-Flórez LJ; Fernández AF; Fraga MF
Clin Epigenetics; 2023 Aug; 15(1):133. PubMed ID: 37612734
[TBL] [Abstract] [Full Text] [Related]
2. Incidence and clinical significance of 491 known fusion genes in a large cohort of Japanese patients with colorectal cancer.
Nanishi K; Hino H; Hatakeyama K; Shiomi A; Kagawa H; Manabe S; Yamaoka Y; Nagashima T; Ohshima K; Urakami K; Akiyama Y; Yamaguchi K
Int J Clin Oncol; 2023 Jun; 28(6):785-793. PubMed ID: 37022622
[TBL] [Abstract] [Full Text] [Related]
3. Cartilage oligomeric matrix protein acts as a molecular biomarker in multiple cancer types.
Guo B; Wang Y; Liu W; Zhang S
Clin Transl Oncol; 2023 Feb; 25(2):535-554. PubMed ID: 36255654
[TBL] [Abstract] [Full Text] [Related]
4. Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer.
Hashimoto T; Takayanagi D; Yonemaru J; Naka T; Nagashima K; Yatabe Y; Shida D; Hamamoto R; Kleeman SO; Leedham SJ; Maughan T; Takashima A; Shiraishi K; Sekine S
Br J Cancer; 2022 Oct; 127(6):1043-1050. PubMed ID: 35715628
[TBL] [Abstract] [Full Text] [Related]
5. Comprehensive genetic characterization of rectal cancer in a large cohort of Japanese patients: differences according to tumor location.
Hino H; Shiomi A; Hatakeyama K; Kagawa H; Manabe S; Yamaoka Y; Nagashima T; Ohshima K; Urakami K; Akiyama Y; Yamaguchi K
J Gastroenterol; 2022 Jul; 57(7):476-485. PubMed ID: 35449312
[TBL] [Abstract] [Full Text] [Related]
6. The role of R-spondin proteins in cancer biology.
Ter Steege EJ; Bakker ERM
Oncogene; 2021 Nov; 40(47):6469-6478. PubMed ID: 34663878
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7. rspo2 silence inhibits tumorigenesis of nasopharyngeal carcinoma by ZNRF3/Hedgehog-Gli1 signal pathway.
Wang Z; Wang Y; Ma X; Dang C
Life Sci; 2021 Oct; 282():119817. PubMed ID: 34273374
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8. R-Spondins 2 and 3 Are Overexpressed in a Subset of Human Colon and Breast cancers.
Conboy CB; Vélez-Reyes GL; Rathe SK; Abrahante JE; Temiz NA; Burns MB; Harris RS; Starr TK; Largaespada DA
DNA Cell Biol; 2021 Jan; 40(1):70-79. PubMed ID: 33320737
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9. A polymorphism within the R-spondin 2 gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab: data from FIRE-3 and TRIBE trials.
Berger MD; Ning Y; Stintzing S; Heinemann V; Cao S; Zhang W; Yang D; Miyamoto Y; Suenaga M; Schirripa M; Hanna DL; Soni S; Puccini A; Tokunaga R; Naseem M; Battaglin F; Cremolini C; Falcone A; Loupakis F; Lenz HJ
Eur J Cancer; 2020 May; 131():89-97. PubMed ID: 32305727
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10. Identification of a novel PRR15L-rspo2 fusion transcript in a sigmoid colon cancer derived from superficially serrated adenoma.
Mizuguchi Y; Sakamoto T; Hashimoto T; Tsukamoto S; Iwasa S; Saito Y; Sekine S
Virchows Arch; 2019 Nov; 475(5):659-663. PubMed ID: 31209633
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11. EIF3E-rspo2 and PIEZO1-rspo2 fusions in colorectal traditional serrated adenoma.
Hashimoto T; Ogawa R; Yoshida H; Taniguchi H; Kojima M; Saito Y; Sekine S
Histopathology; 2019 Aug; 75(2):266-273. PubMed ID: 30916365
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12. Molecular genetics and targeted therapy of WNT-related human diseases (Review).
Katoh M; Katoh M
Int J Mol Med; 2017 Sep; 40(3):587-606. PubMed ID: 28731148
[TBL] [Abstract] [Full Text] [Related]
13. R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine.
Han T; Schatoff EM; Murphy C; Zafra MP; Wilkinson JE; Elemento O; Dow LE
Nat Commun; 2017 Jul; 8():15945. PubMed ID: 28695896
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14. rspo2 suppresses colorectal cancer metastasis by counteracting the Wnt5a/Fzd7-driven noncanonical Wnt pathway.
Dong X; Liao W; Zhang L; Tu X; Hu J; Chen T; Dai X; Xiong Y; Liang W; Ding C; Liu R; Dai J; Wang O; Lu L; Lu X
Cancer Lett; 2017 Aug; 402():153-165. PubMed ID: 28600110
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15. Comprehensive characterization of RSPO fusions in colorectal traditional serrated adenomas.
Sekine S; Ogawa R; Hashimoto T; Motohiro K; Yoshida H; Taniguchi H; Saito Y; Yasuhiro O; Ochiai A; Hiraoka N
Histopathology; 2017 Oct; 71(4):601-609. PubMed ID: 28543708
[TBL] [Abstract] [Full Text] [Related]
16. Abnormal expression of mRNA, microRNA alteration and aberrant DNA methylation patterns in rectal adenocarcinoma.
Hua Y; Ma X; Liu X; Yuan X; Qin H; Zhang X
PLoS One; 2017; 12(3):e0174461. PubMed ID: 28350845
[TBL] [Abstract] [Full Text] [Related]
17. Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.
Gong X; Yi J; Carmon KS; Crumbley CA; Xiong W; Thomas A; Fan X; Guo S; An Z; Chang JT; Liu QJ
Oncogene; 2015 Sep; 34(36):4692-701. PubMed ID: 25531322
[TBL] [Abstract] [Full Text] [Related]
18. RSPO fusion transcripts in colorectal cancer in Japanese population.
Shinmura K; Kahyo T; Kato H; Igarashi H; Matsuura S; Nakamura S; Kurachi K; Nakamura T; Ogawa H; Funai K; Tanahashi M; Niwa H; Sugimura H
Mol Biol Rep; 2014 Aug; 41(8):5375-84. PubMed ID: 24847761
[TBL] [Abstract] [Full Text] [Related]
19. rspo2-LGR5 signaling has tumour-suppressive activity in colorectal cancer.
Wu C; Qiu S; Lu L; Zou J; Li WF; Wang O; Zhao H; Wang H; Tang J; Chen L; Xu T; Sun Z; Liao W; Luo G; Lu X
Nat Commun; 2014; 5():3149. PubMed ID: 24476626
[TBL] [Abstract] [Full Text] [Related]
20. Recurrent R-spondin fusions in colon cancer.
Seshagiri S; Stawiski EW; Durinck S; Modrusan Z; Storm EE; Conboy CB; Chaudhuri S; Guan Y; Janakiraman V; Jaiswal BS; Guillory J; Ha C; Dijkgraaf GJ; Stinson J; Gnad F; Huntley MA; Degenhardt JD; Haverty PM; Bourgon R; Wang W; Koeppen H; Gentleman R; Starr TK; Zhang Z; Largaespada DA; Wu TD; de Sauvage FJ
Nature; 2012 Aug; 488(7413):660-4. PubMed ID: 22895193
[TBL] [Abstract] [Full Text] [Related]
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