Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND SMAD3, JV15-2, 4088, ENSG00000166949, P84022, Smad3, MADH3, HsT17436, Smad 3, DKFZp686J10186, HSPC193, DKFZP586N0721, MGC60396 AND Treatment
24 results:

  • 1. OLFM2 promotes epithelial-mesenchymal transition, migration, and invasion in colorectal cancer through the TGF-β/smad signaling pathway.
    Tang Y; Liu Y; Wang X; Guo H; Chen L; Hu G; Cui Y; Liang S; Zuo J; Luo Z; Chen X; Wang X
    BMC Cancer; 2024 Feb; 24(1):204. PubMed ID: 38350902
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Linderapyrone analogue LPD-01 as a cancer treatment agent by targeting importin7.
    Kitagawa T; Matsumoto T; Ohta T; Yoshida T; Saito Y; Nakayama Y; Hadate Y; Ashihara E; Watanabe T
    J Nat Med; 2024 Mar; 78(2):370-381. PubMed ID: 38265612
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art.
    Lu G; Wang X; Cheng M; Wang S; Ma K
    Biomed Pharmacother; 2023 Sep; 165():115132. PubMed ID: 37423169
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Activin A/ACVR2A axis inhibits epithelial-to-mesenchymal transition in colon cancer by activating smad2.
    Zhang H; Ruan Q; Chen C; Yu H; Guan S; Hu D; Yang C; Lin R; Zhuo C
    Mol Carcinog; 2023 Oct; 62(10):1585-1598. PubMed ID: 37378449
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Long-read sequencing identifies novel structural variations in colorectal cancer.
    Xu L; Wang X; Lu X; Liang F; Liu Z; Zhang H; Li X; Tian S; Wang L; Wang Z
    PLoS Genet; 2023 Feb; 19(2):e1010514. PubMed ID: 36812239
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Prolyl 4-hydroxylase subunit alpha 3 facilitates human colon cancer growth and metastasis through the TGF-β/smad signaling pathway.
    Zhou H; Zou J; Shao C; Zhou A; Yu J; Chen S; Xu C
    Pathol Res Pract; 2022 Feb; 230():153749. PubMed ID: 34959098
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Melatonin and hyperbaric oxygen therapies suppress colorectal carcinogenesis through pleiotropic effects and multifaceted mechanisms.
    Li YC; Chen CH; Chang CL; Chiang JY; Chu CH; Chen HH; Yip HK
    Int J Biol Sci; 2021; 17(14):3728-3744. PubMed ID: 34671196
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. CaMKII Mediates TGFβ1-Induced Fibroblasts Activation and Its Cross Talk with Colon cancer Cells.
    Chen W; Chen Y; Su J; Kang J; Ding Y; Ai W; Zhang J; Luo H; An P
    Dig Dis Sci; 2022 Jan; 67(1):134-145. PubMed ID: 33528688
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Vemurafenib downmodulates aggressiveness mediators of colorectal cancer (CRC): Low Molecular Weight Protein Tyrosine Phosphatase (LMWPTP), Protein Tyrosine Phosphatase 1B (PTP1B) and Transforming Growth Factor β (TGFβ).
    Cordeiro HG; de Sousa Faria AV; Ferreira-Halder CV
    Biol Chem; 2020 Aug; 401(9):1063-1069. PubMed ID: 32229687
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. 20(S)-ginsenoside Rh2 as agent for the treatment of LMN-CRC via regulating epithelial-mesenchymal transition.
    Yuan Y; Wang J; Xu M; Zhang Y; Wang Z; Liang L; Sun P
    Biosci Rep; 2020 Mar; 40(3):. PubMed ID: 32141497
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer.
    Luo K; Geng J; Zhang Q; Xu Y; Zhou X; Huang Z; Shi KQ; Pan C; Wu J
    J Exp Clin Cancer Res; 2019 Jun; 38(1):249. PubMed ID: 31186036
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Tumour necrosis factor-α-induced protein 8-like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells.
    Wu DD; Liu SY; Gao YR; Lu D; Hong Y; Chen YG; Dong PZ; Wang DY; Li T; Li HM; Ren ZG; Guo JC; He F; Ren XQ; Sun SY; Duan SF; Ji XY
    J Cell Mol Med; 2019 Mar; 23(3):1698-1713. PubMed ID: 30637920
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. smad4 Inhibits VEGF-A and VEGF-C Expressions via Enhancing smad3 Phosphorylation in Colon cancer.
    Li X; Li X; Lv X; Xiao J; Liu B; Zhang Y
    Anat Rec (Hoboken); 2017 Sep; 300(9):1560-1569. PubMed ID: 28445620
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. TGFβ/smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells.
    Bailey KL; Agarwal E; Chowdhury S; Luo J; Brattain MG; Black JD; Wang J
    PLoS One; 2017; 12(4):e0176096. PubMed ID: 28414818
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Tolfenamic acid downregulates β-catenin in colon cancer.
    Ha T; Lou Z; Baek SJ; Lee SH
    Int Immunopharmacol; 2016 Jun; 35():287-293. PubMed ID: 27089389
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells.
    Romano G; Santi L; Bianco MR; Giuffrè MR; Pettinato M; Bugarin C; Garanzini C; Savarese L; Leoni S; Cerrito MG; Leone BE; Gaipa G; Grassilli E; Papa M; Lavitrano M; Giovannoni R
    Oncotarget; 2016 Apr; 7(16):22077-91. PubMed ID: 26956045
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Predictive role of microRNA-related genetic polymorphisms in the pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients.
    Dreussi E; Pucciarelli S; De Paoli A; Polesel J; Canzonieri V; Agostini M; Friso ML; Belluco C; Buonadonna A; Lonardi S; Zanusso C; De Mattia E; Toffoli G; Cecchin E
    Oncotarget; 2016 Apr; 7(15):19781-93. PubMed ID: 26934318
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. DNA methylation levels and long-term trihalomethane exposure in drinking water: an epigenome-wide association study.
    Salas LA; Bustamante M; Gonzalez JR; Gracia-Lavedan E; Moreno V; Kogevinas M; Villanueva CM
    Epigenetics; 2015; 10(7):650-61. PubMed ID: 26039576
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Notch-1 promotes stemness and epithelial to mesenchymal transition in colorectal cancer.
    Fender AW; Nutter JM; Fitzgerald TL; Bertrand FE; Sigounas G
    J Cell Biochem; 2015 Nov; 116(11):2517-27. PubMed ID: 25914224
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Small can be beautiful: 10 years managing colorectal cancer in a rural general hospital.
    Grant AJ; Sedgwick DM
    Scott Med J; 2011 Feb; 56(1):26-9. PubMed ID: 21515529
    [TBL] [Abstract] [Full Text] [Related]  


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