Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND SMAD4, JIP, Q13485, 4089, ENSG00000141646, MADH4, DPC4
627 results:

  • 1. A pair of primary colorectal cancer-derived and corresponding synchronous liver metastasis-derived organoid cell lines.
    Cheng F; Li P; Xu S; Zhang C; Liang H; Ding Z
    Aging (Albany NY); 2024 Feb; 16(5):4396-4422. PubMed ID: 38407980
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Multi-omic profiling reveals associations between the gut microbiome, host genome and transcriptome in patients with colorectal cancer.
    Zou S; Yang C; Zhang J; Zhong D; Meng M; Zhang L; Chen H; Fang L
    J Transl Med; 2024 Feb; 22(1):175. PubMed ID: 38369542
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Biological background of colorectal polyps and carcinomas with heterotopic ossification: A national study and literature review.
    Vos AM; Pijnenborg L; van Vliet S; Kodach LL; Ciompi F; van der Post RS; Simmer F; Nagtegaal ID
    Hum Pathol; 2024 Mar; 145():34-41. PubMed ID: 38367815
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Integrating cfDNA liquid biopsy and organoid-based drug screening reveals PI3K signaling as a promising therapeutic target in colorectal cancer.
    Yang H; Xiao X; Zeng L; Zeng H; Zheng Y; Wang J; Li G; Dai W; He Y; Wang S; Peng J; Chen W
    J Transl Med; 2024 Feb; 22(1):132. PubMed ID: 38310289
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. TIF1γ and smad4 regulation in colorectal cancer: impact on cell proliferation and liver metastasis.
    Wu Y; Yu B; Ai X; Zhang W; Chen W; Laurence A; Zhang M; Chen Q; Shao Y; Zhang B
    Biol Chem; 2024 Apr; 405(4):241-256. PubMed ID: 38270141
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Clinical-Molecular characteristics and Post-Translational modifications of colorectal cancer in north China: Implications for future targeted therapies.
    Chi Y; Yuan H; Fan Q; Wang Z; Niu Z; Yu J; Yuan D
    Gene; 2024 Mar; 899():148134. PubMed ID: 38185290
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Sotorasib with panitumumab in chemotherapy-refractory KRAS
    Kuboki Y; Fakih M; Strickler J; Yaeger R; Masuishi T; Kim EJ; Bestvina CM; Kopetz S; Falchook GS; Langer C; Krauss J; Puri S; Cardona P; Chan E; Varrieur T; Mukundan L; Anderson A; Tran Q; Hong DS
    Nat Med; 2024 Jan; 30(1):265-270. PubMed ID: 38177853
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Local Therapy Improves Survival for Early Recurrence After Resection of colorectal Liver Metastases.
    Boyev A; Tzeng CD; Maki H; Arvide EM; Mrema DE; Jain AJ; Haddad A; Lendoire M; Malik N; Odisio BC; Chun YS; Tran Cao HS; Vauthey JN; Newhook TE
    Ann Surg Oncol; 2024 Apr; 31(4):2547-2556. PubMed ID: 38148351
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Genetic profile of Chinese patients with small bowel cancer categorized by anatomic location.
    Shi C; Ma J; Zhang T; Shi Y; Duan W; Huang D; Zhang H; Zeng Y
    BMC Med Genomics; 2023 Nov; 16(1):289. PubMed ID: 37974218
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Loss of SETD2 aggravates colorectal cancer progression caused by smad4 deletion through the RAS/ERK signalling pathway.
    Ma C; Liu M; Feng W; Rao H; Zhang W; Liu C; Xu Y; Wang Z; Teng Y; Yang X; Ni L; Xu J; Gao WQ; Lu B; Li L
    Clin Transl Med; 2023 Nov; 13(11):e1475. PubMed ID: 37962020
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Stromal BMP signaling regulates mucin production in the large intestine via interleukin-1/17.
    Wang Y; Lou R; Zhang Z; Xiao C; Yu S; Wei S; Liu Y; Fu W; Li B; Chen YG
    Sci Adv; 2023 Oct; 9(43):eadi1827. PubMed ID: 37889976
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Chanling Gao suppresses colorectal cancer via PI3K/Akt/mTOR pathway modulation and enhances quality of survival.
    Chen G; Tian TT; Wang FQ; Pan CS; Sun K; Wang XY; Yang B; Yang Z; Tang DX; Han JY
    Environ Toxicol; 2024 Mar; 39(3):1107-1118. PubMed ID: 37823609
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. TP53 Alteration and Its Effect on Pathologic Response Are Associated with Survival after Resection of colorectal Liver Metastases.
    Maki H; Haddad A; Ayabe RI; Lendoire M; Khanduri I; Maru DM; Vauthey JN
    J Gastrointest Surg; 2023 Nov; 27(11):2597-2600. PubMed ID: 37553514
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Genome-wide CRISPR Screen Reveals RAB10 as a Synthetic Lethal Gene in colorectal and Pancreatic cancers Carrying smad4 Loss.
    Erasimus H; Kolnik V; Lacroix F; Sidhu S; D'Agostino S; Lemaitre O; Rohaut A; Sanchez I; Thill G; Didier M; Debussche L; Marcireau C
    Cancer Res Commun; 2023 May; 3(5):780-792. PubMed ID: 37377893
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. To Assess the Role of microRNA-451 in the Progression and Metastasis of colorectal cancer.
    Chen H; Yao J; Shan Z; Wei Y; You S; Li D; Zhang Y
    Appl Biochem Biotechnol; 2024 Feb; 196(2):1044-1057. PubMed ID: 37318687
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. TGFβ and the Tumor Microenvironment in colorectal cancer.
    Waldner MJ; Neurath MF
    Cells; 2023 Apr; 12(8):. PubMed ID: 37190048
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Downregulated miR-495-3p in colorectal cancer targets TGFβR1, TGFβR2, smad4 and BUB1 genes and induces cell cycle arrest.
    Kabiri F; Medlej A; Saleh AJ; Aghdami N; Khani M; Soltani BM
    Cancer Treat Res Commun; 2023; 35():100702. PubMed ID: 37044020
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Oncogenic signaling is coupled to colorectal cancer cell differentiation state.
    Sell T; Klotz C; Fischer MM; Astaburuaga-García R; Krug S; Drost J; Clevers H; Sers C; Morkel M; Blüthgen N
    J Cell Biol; 2023 Jun; 222(6):. PubMed ID: 37017636
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. PRMT5 methylating smad4 activates TGF-β signaling and promotes colorectal cancer metastasis.
    Liu A; Yu C; Qiu C; Wu Q; Huang C; Li X; She X; Wan K; Liu L; Li M; Wang Z; Chen Y; Hu F; Song D; Li K; Zhao C; Deng H; Sun X; Xu F; Lai S; Luo X; Hu J; Wang G
    Oncogene; 2023 May; 42(19):1572-1584. PubMed ID: 36991117
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Imatinib blocks tyrosine phosphorylation of smad4 and restores TGF-β growth-suppressive signaling in BCR-ABL1-positive leukemia.
    Wang L; Gu S; Chen F; Yu Y; Cao J; Li X; Gao C; Chen Y; Yuan S; Liu X; Qin J; Zhao B; Xu P; Liang T; Tong H; Lin X; Feng XH
    Signal Transduct Target Ther; 2023 Mar; 8(1):120. PubMed ID: 36959211
    [TBL] [Abstract] [Full Text] [Related]  


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