Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND SMAD4, JIP, Q13485, 4089, ENSG00000141646, MADH4, DPC4 AND Treatment
132 results:

  • 1. Integrating cfDNA liquid biopsy and organoid-based drug screening reveals PI3K signaling as a promising therapeutic target in colorectal cancer.
    Yang H; Xiao X; Zeng L; Zeng H; Zheng Y; Wang J; Li G; Dai W; He Y; Wang S; Peng J; Chen W
    J Transl Med; 2024 Feb; 22(1):132. PubMed ID: 38310289
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Sotorasib with panitumumab in chemotherapy-refractory KRAS
    Kuboki Y; Fakih M; Strickler J; Yaeger R; Masuishi T; Kim EJ; Bestvina CM; Kopetz S; Falchook GS; Langer C; Krauss J; Puri S; Cardona P; Chan E; Varrieur T; Mukundan L; Anderson A; Tran Q; Hong DS
    Nat Med; 2024 Jan; 30(1):265-270. PubMed ID: 38177853
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Local Therapy Improves Survival for Early Recurrence After Resection of colorectal Liver Metastases.
    Boyev A; Tzeng CD; Maki H; Arvide EM; Mrema DE; Jain AJ; Haddad A; Lendoire M; Malik N; Odisio BC; Chun YS; Tran Cao HS; Vauthey JN; Newhook TE
    Ann Surg Oncol; 2024 Apr; 31(4):2547-2556. PubMed ID: 38148351
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  • 4. Loss of SETD2 aggravates colorectal cancer progression caused by smad4 deletion through the RAS/ERK signalling pathway.
    Ma C; Liu M; Feng W; Rao H; Zhang W; Liu C; Xu Y; Wang Z; Teng Y; Yang X; Ni L; Xu J; Gao WQ; Lu B; Li L
    Clin Transl Med; 2023 Nov; 13(11):e1475. PubMed ID: 37962020
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  • 5. Genome-wide CRISPR Screen Reveals RAB10 as a Synthetic Lethal Gene in colorectal and Pancreatic cancers Carrying smad4 Loss.
    Erasimus H; Kolnik V; Lacroix F; Sidhu S; D'Agostino S; Lemaitre O; Rohaut A; Sanchez I; Thill G; Didier M; Debussche L; Marcireau C
    Cancer Res Commun; 2023 May; 3(5):780-792. PubMed ID: 37377893
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  • 6. PRMT5 methylating smad4 activates TGF-β signaling and promotes colorectal cancer metastasis.
    Liu A; Yu C; Qiu C; Wu Q; Huang C; Li X; She X; Wan K; Liu L; Li M; Wang Z; Chen Y; Hu F; Song D; Li K; Zhao C; Deng H; Sun X; Xu F; Lai S; Luo X; Hu J; Wang G
    Oncogene; 2023 May; 42(19):1572-1584. PubMed ID: 36991117
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  • 7. Lantern-shaped flexible RNA origami for smad4 mRNA delivery and growth suppression of colorectal cancer.
    Hu M; Feng C; Yuan Q; Liu C; Ge B; Sun F; Zhu X
    Nat Commun; 2023 Mar; 14(1):1307. PubMed ID: 36894556
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Analysis Of Common Somatic Mutations In colorectal Carcinoma And Associated Dysregulated Pathwaysarts.
    Hassan S; Khatoon A; Bukhari U; Mirza T
    J Ayub Med Coll Abbottabad; 2023; 35(1):137-143. PubMed ID: 36849394
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Fistula-Associated Anal Adenocarcinoma: A 20-Year Single-Center Experience.
    Harpain F; Dawoud C; Wimmer K; Schlager L; Kirchnawy S; Rizk D; Girgis K; Mittermair E; Oberndorfer F; Wöran K; Riss S; Stift A; Stift J
    Ann Surg Oncol; 2023 Jun; 30(6):3517-3527. PubMed ID: 36757514
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The Cytokine Network in colorectal cancer: Implications for New treatment Strategies.
    Braumüller H; Mauerer B; Andris J; Berlin C; Wieder T; Kesselring R
    Cells; 2022 Dec; 12(1):. PubMed ID: 36611932
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Identification of liquid biopsy-based mutations in colorectal cancer by targeted sequencing assays.
    Szász I; Kiss T; Mokánszki A; Koroknai V; Deák J; Patel V; Jámbor K; Ádány R; Balázs M
    Mol Cell Probes; 2023 Feb; 67():101888. PubMed ID: 36513244
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Clonal evolution and expansion associated with therapy resistance and relapse of colorectal cancer.
    S A; Chakraborty A; Patnaik S
    Mutat Res Rev Mutat Res; 2022; 790():108445. PubMed ID: 36371022
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The first comprehensive genomic characterization of rectal squamous cell carcinoma.
    Astaras C; De Vito C; Chaskar P; Bornand A; Khanfir K; Sciarra A; Letovanec I; Corro C; Dietrich PY; Tsantoulis P; Koessler T
    J Gastroenterol; 2023 Feb; 58(2):125-134. PubMed ID: 36357817
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. smad4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, colorectal cancer Growth, and Metastasis.
    Loevenich LP; Tschurtschenthaler M; Rokavec M; Silva MG; Jesinghaus M; Kirchner T; Klauschen F; Saur D; Neumann J; Hermeking H; Jung P
    Cancer Res; 2022 Dec; 82(24):4604-4623. PubMed ID: 36219392
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Monitoring tumour resistance to the BRAF inhibitor combination regimen in colorectal cancer patients via circulating tumour DNA.
    Ye LF; Huang ZY; Chen XX; Chen ZG; Wu SX; Ren C; Hu MT; Bao H; Jin Y; Wang F; Wang FH; Du ZM; Wu X; Ju HQ; Shao Y; Li YH; Xu RH; Wang DS
    Drug Resist Updat; 2022 Dec; 65():100883. PubMed ID: 36202008
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Regulation of transforming growth factor-β signaling as a therapeutic approach to treating colorectal cancer.
    Maslankova J; Vecurkovska I; Rabajdova M; Katuchova J; Kicka M; Gayova M; Katuch V
    World J Gastroenterol; 2022 Sep; 28(33):4744-4761. PubMed ID: 36156927
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. smad4-deficient T cells promote colitis-associated colon cancer
    Choi SH; Huang AY; Letterio JJ; Kim BG
    Front Immunol; 2022; 13():932412. PubMed ID: 36045676
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Prospective Study of Perioperative Circulating Tumor DNA Dynamics in Patients Undergoing Hepatectomy for colorectal Liver Metastases.
    Newhook TE; Overman MJ; Chun YS; Dasari A; Tzeng CD; Cao HST; Raymond V; Parseghian C; Johnson B; Nishioka Y; Kawaguchi Y; Uppal A; Vreeland TJ; Jaimovich A; Arvide EM; Cristo JV; Wei SH; Raghav KP; Morris VK; Lee JE; Kopetz S; Vauthey JN
    Ann Surg; 2023 May; 277(5):813-820. PubMed ID: 35797554
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. TGF-β-Induced FLRT3 Attenuation Is Essential for cancer-Associated Fibroblast-Mediated Epithelial-Mesenchymal Transition in colorectal cancer.
    Yang M; Li D; Jiang Z; Li C; Ji S; Sun J; Chang Y; Ruan S; Wang Z; Liang R; Dai X; Li B; Zhao H
    Mol Cancer Res; 2022 Aug; 20(8):1247-1259. PubMed ID: 35560224
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Use of Cabozantinib to Treat MET -amplified Pediatric colorectal cancer.
    Fukui S; Umeda K; Kubota H; Iwai A; Akazawa R; Isobe K; Tanaka K; Kouzuki K; Kawabata N; Saida S; Kato I; Hiramatsu H; Itatani Y; Funakoshi T; Adachi S; Takita J
    J Pediatr Hematol Oncol; 2023 Apr; 45(3):e423-e426. PubMed ID: 35536994
    [TBL] [Abstract] [Full Text] [Related]  


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